Detailed information NTG1141525

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN29_RS07825
• Genome accession: NZ_LS483437
• Coordinates: 1476219..1476944 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13751
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1471219..1481944

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN29_RS07790 (NCTC13751_01565)	rnpM	1471253..1471549 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQN29_RS07795 (NCTC13751_01566)	nusA	1471565..1472722 (-)	1158	WP_002988817.1	transcription termination factor NusA	-
DQN29_RS07800 (NCTC13751_01567)	rimP	1472897..1473433 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQN29_RS07810 (NCTC13751_01569)	trmB	1473692..1474327 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN29_RS07815 (NCTC13751_01570)	ccrZ	1474327..1475118 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN29_RS07820 (NCTC13751_01571)	-	1475182..1476216 (-)	1035	WP_023610531.1	ABC transporter permease	-
DQN29_RS07825 (NCTC13751_01572)	pptA	1476219..1476944 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN29_RS07830 (NCTC13751_01573)	-	1477016..1477435 (+)	420	WP_011285081.1	HIT family protein	-
DQN29_RS07835 (NCTC13751_01574)	-	1477432..1477788 (+)	357	WP_020905404.1	hypothetical protein	-
DQN29_RS07840 (NCTC13751_01575)	brpA	1477899..1479173 (-)	1275	WP_020837594.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN29_RS07845 (NCTC13751_01576)	-	1479182..1479706 (-)	525	WP_030126880.1	GNAT family N-acetyltransferase	-
DQN29_RS07850 (NCTC13751_01577)	tsaE	1479681..1480142 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN29_RS07855 (NCTC13751_01578)	-	1480296..1481756 (-)	1461	WP_023609915.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1141525 DQN29_RS07825 WP_002983379.1 1476219..1476944(-) (pptA) [Streptococcus pyogenes strain NCTC13751]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1141525 DQN29_RS07825 WP_002983379.1 1476219..1476944(-) (pptA) [Streptococcus pyogenes strain NCTC13751]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714