Detailed information NTG1141518

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQN29_RS06655
• Genome accession: NZ_LS483437
• Coordinates: 1267331..1268368 (-)
• Length: 345 a.a.
• NCBI ID: WP_076639313.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13751
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1262331..1273368

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN29_RS06635 (NCTC13751_01342)	-	1263081..1263707 (+)	627	WP_002983834.1	prepilin peptidase	-
DQN29_RS06640 (NCTC13751_01343)	rlmN	1263789..1264868 (-)	1080	WP_020905325.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQN29_RS06645 (NCTC13751_01344)	-	1264872..1265492 (-)	621	WP_002992791.1	YutD family protein	-
DQN29_RS06650 (NCTC13751_01346)	-	1265940..1266917 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
DQN29_RS06655 (NCTC13751_01347)	sepM	1267331..1268368 (-)	1038	WP_076639313.1	SepM family pheromone-processing serine protease	Regulator
DQN29_RS06660 (NCTC13751_01348)	coaD	1268355..1268846 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQN29_RS06665 (NCTC13751_01349)	rsmD	1268836..1269375 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQN29_RS06670 (NCTC13751_01350)	asnA	1269498..1270490 (-)	993	WP_020905328.1	aspartate--ammonia ligase	-
DQN29_RS06675 (NCTC13751_01351)	arcC	1270803..1271753 (-)	951	WP_010922501.1	carbamate kinase	-
DQN29_RS06680 (NCTC13751_01352)	-	1271773..1273104 (-)	1332	WP_011054719.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.27 Da
• Isoelectric Point: 9.6692

>NTDB_id=1141518 DQN29_RS06655 WP_076639313.1 1267331..1268368(-) (sepM) [Streptococcus pyogenes strain NCTC13751]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLTDTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1141518 DQN29_RS06655 WP_076639313.1 1267331..1268368(-) (sepM) [Streptococcus pyogenes strain NCTC13751]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGATGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAACAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69