Detailed information NTG1141347

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN32_RS07450
• Genome accession: NZ_LS483432
• Coordinates: 1424293..1425018 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13745
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1419293..1430018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN32_RS07415 (NCTC13745_01474)	rnpM	1419327..1419623 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQN32_RS07420 (NCTC13745_01475)	nusA	1419639..1420796 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQN32_RS07425 (NCTC13745_01476)	rimP	1420971..1421507 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQN32_RS07435 (NCTC13745_01478)	trmB	1421766..1422401 (-)	636	WP_031488472.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN32_RS07440 (NCTC13745_01479)	ccrZ	1422401..1423192 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN32_RS07445 (NCTC13745_01480)	-	1423256..1424290 (-)	1035	WP_031577431.1	ABC transporter permease	-
DQN32_RS07450 (NCTC13745_01481)	pptA	1424293..1425018 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN32_RS07455 (NCTC13745_01482)	-	1425090..1425509 (+)	420	WP_002983376.1	HIT family protein	-
DQN32_RS07460 (NCTC13745_01483)	-	1425506..1425862 (+)	357	WP_031488470.1	hypothetical protein	-
DQN32_RS07465 (NCTC13745_01484)	brpA	1425973..1427256 (-)	1284	WP_111681976.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN32_RS07470 (NCTC13745_01485)	-	1427265..1427789 (-)	525	WP_031488468.1	GNAT family N-acetyltransferase	-
DQN32_RS07475 (NCTC13745_01486)	tsaE	1427764..1428225 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN32_RS07480 (NCTC13745_01487)	-	1428379..1429839 (-)	1461	WP_031488467.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1141347 DQN32_RS07450 WP_002983379.1 1424293..1425018(-) (pptA) [Streptococcus pyogenes strain NCTC13745]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1141347 DQN32_RS07450 WP_002983379.1 1424293..1425018(-) (pptA) [Streptococcus pyogenes strain NCTC13745]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714