Detailed information
Bioinformatically predicted
Overview
| Name | pepF | Type | Regulator |
| Locus tag | DQN32_RS05915 | Genome accession | NZ_LS483432 |
| Coordinates | 1139245..1141050 (-) | Length | 601 a.a. |
| NCBI ID | WP_011054652.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain NCTC13745 | ||
| Function | degradation of XIP; competence shut-off (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1119015..1166084 | 1139245..1141050 | within | 0 |
Gene organization within MGE regions
Location: 1119015..1166084
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQN32_RS05835 (NCTC13745_01161) | - | 1119053..1120327 (-) | 1275 | WP_020837316.1 | polysaccharide deacetylase family protein | - |
| DQN32_RS05840 (NCTC13745_01162) | - | 1120422..1121849 (-) | 1428 | WP_011284931.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| DQN32_RS05845 (NCTC13745_01163) | ptsP | 1122034..1123767 (-) | 1734 | WP_002984033.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| DQN32_RS05850 (NCTC13745_01164) | - | 1123772..1124035 (-) | 264 | WP_002984031.1 | phosphocarrier protein HPr | - |
| DQN32_RS05855 (NCTC13745_01165) | - | 1124428..1124646 (+) | 219 | WP_002989242.1 | redoxin NrdH | - |
| DQN32_RS05860 (NCTC13745_01166) | nrdE | 1124666..1126825 (+) | 2160 | WP_031488773.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| DQN32_RS05865 (NCTC13745_01167) | nrdF | 1127158..1128117 (+) | 960 | WP_002987365.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| DQN32_RS05870 (NCTC13745_01168) | - | 1128179..1129405 (+) | 1227 | WP_021340858.1 | chloride channel protein | - |
| DQN32_RS05875 | - | 1129501..1130658 (+) | 1158 | Protein_1088 | IS3 family transposase | - |
| DQN32_RS05880 (NCTC13745_01172) | - | 1130750..1131445 (-) | 696 | WP_031488553.1 | CPBP family intramembrane glutamic endopeptidase | - |
| DQN32_RS05885 (NCTC13745_01173) | - | 1131464..1132225 (-) | 762 | WP_031488552.1 | DUF3169 family protein | - |
| DQN32_RS05890 (NCTC13745_01174) | - | 1132222..1132437 (-) | 216 | WP_002989220.1 | helix-turn-helix transcriptional regulator | - |
| DQN32_RS05895 (NCTC13745_01176) | alaS | 1132777..1135395 (-) | 2619 | WP_031488551.1 | alanine--tRNA ligase | - |
| DQN32_RS05900 (NCTC13745_01178) | prsA | 1135782..1136837 (-) | 1056 | WP_002984003.1 | peptidylprolyl isomerase PrsA | - |
| DQN32_RS05905 (NCTC13745_01179) | - | 1136900..1137607 (-) | 708 | WP_002984000.1 | O-methyltransferase | - |
| DQN32_RS05910 (NCTC13745_01180) | - | 1137673..1138869 (-) | 1197 | WP_002995765.1 | OFA family MFS transporter | - |
| DQN32_RS05915 (NCTC13745_01181) | pepF | 1139245..1141050 (-) | 1806 | WP_011054652.1 | oligoendopeptidase F | Regulator |
| DQN32_RS05920 (NCTC13745_01182) | - | 1141063..1142025 (-) | 963 | WP_031488550.1 | competence protein CoiA | - |
| DQN32_RS05925 (NCTC13745_01183) | - | 1142321..1143037 (-) | 717 | WP_002995774.1 | pseudouridine synthase | - |
| DQN32_RS05930 (NCTC13745_01184) | nagB | 1143156..1143860 (-) | 705 | WP_002995779.1 | glucosamine-6-phosphate deaminase | - |
| DQN32_RS05935 (NCTC13745_01185) | queA | 1144062..1145090 (+) | 1029 | WP_031488549.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| DQN32_RS05940 (NCTC13745_01186) | - | 1145097..1146317 (+) | 1221 | WP_002983986.1 | DUF3114 domain-containing protein | - |
| DQN32_RS05945 (NCTC13745_01187) | - | 1146471..1147061 (-) | 591 | WP_002983984.1 | serine hydrolase | - |
| DQN32_RS09635 | - | 1147058..1147285 (-) | 228 | WP_226316535.1 | hypothetical protein | - |
| DQN32_RS05955 (NCTC13745_01188) | - | 1147286..1147519 (-) | 234 | WP_002983979.1 | hypothetical protein | - |
| DQN32_RS05960 (NCTC13745_01189) | sodA | 1147686..1148291 (-) | 606 | WP_002983977.1 | superoxide dismutase SodA | - |
| DQN32_RS05965 (NCTC13745_01190) | holA | 1148388..1149428 (-) | 1041 | WP_031488548.1 | DNA polymerase III subunit delta | - |
| DQN32_RS05970 (NCTC13745_01191) | - | 1149499..1151742 (-) | 2244 | WP_031488547.1 | DNA internalization-related competence protein ComEC/Rec2 | - |
| DQN32_RS05975 (NCTC13745_01192) | - | 1151723..1152385 (-) | 663 | WP_002983967.1 | ComEA family DNA-binding protein | - |
| DQN32_RS05980 (NCTC13745_01193) | - | 1152585..1153325 (-) | 741 | WP_031488546.1 | lysophospholipid acyltransferase family protein | - |
| DQN32_RS05985 (NCTC13745_01194) | - | 1153443..1154219 (+) | 777 | WP_010922438.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| DQN32_RS05990 (NCTC13745_01195) | - | 1154209..1154487 (+) | 279 | WP_011017953.1 | GIY-YIG nuclease family protein | - |
| DQN32_RS05995 (NCTC13745_01196) | - | 1154511..1156511 (-) | 2001 | WP_031488545.1 | potassium transporter Kup | - |
| DQN32_RS06000 (NCTC13745_01197) | - | 1156638..1158257 (-) | 1620 | WP_002989158.1 | DEAD/DEAH box helicase | - |
| DQN32_RS06005 (NCTC13745_01198) | - | 1158564..1160108 (-) | 1545 | WP_031488544.1 | peptide chain release factor 3 | - |
| DQN32_RS06015 (NCTC13745_01199) | - | 1160356..1161051 (-) | 696 | WP_031488543.1 | TIGR02206 family membrane protein | - |
| DQN32_RS06020 (NCTC13745_01200) | - | 1161131..1162522 (-) | 1392 | WP_031488542.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| DQN32_RS06025 (NCTC13745_01201) | - | 1162713..1163759 (-) | 1047 | WP_002989146.1 | D-alanine--D-alanine ligase | - |
| DQN32_RS06030 (NCTC13745_01202) | recR | 1163860..1164456 (-) | 597 | WP_002983939.1 | recombination mediator RecR | - |
| DQN32_RS09765 | - | 1164503..1164694 (-) | 192 | WP_002983936.1 | hypothetical protein | - |
| DQN32_RS06040 (NCTC13745_01203) | - | 1165253..1166032 (-) | 780 | WP_014407680.1 | formate/nitrite transporter family protein | - |
Sequence
Protein
Download Length: 601 a.a. Molecular weight: 69341.19 Da Isoelectric Point: 4.7093
>NTDB_id=1141337 DQN32_RS05915 WP_011054652.1 1139245..1141050(-) (pepF) [Streptococcus pyogenes strain NCTC13745]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFSGHLLDSSANLLTITDTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFSGHLLDSSANLLTITDTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSIRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS
Nucleotide
Download Length: 1806 bp
>NTDB_id=1141337 DQN32_RS05915 WP_011054652.1 1139245..1141050(-) (pepF) [Streptococcus pyogenes strain NCTC13745]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAATTGACGCGGCTAAGGATTTTTCAGGTCATTTACTAGATTCTAGCGCTAATC
TGTTGACAATTACAGATACTTATTTAGAGTTAGCTCGTCGTGTTGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTGTTTTC
ATTCTATGACCCAGAAGTTATGGCATTGAGTCAGGAAGATTACCAAGCTTTTCTTGCGGAAACACCTGATTTAAAAAGGT
ATCATCATTTCTTTGACAAATTGTTCCAGACACGTGACCATGTGCTCAGCCAGGCTGAAGAGGAATTATTAGCAGGAGCC
CAAGAAATTTTCAACGGCGCTGAAGAAACCTTTAGTATTCTTGATAACGCTGATATTGTCTTTCCAGTAGTTAAAAATGA
TAAGGGGGAAGATGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCATTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGATACCTTGTTAGAAACGGTTAATAAACATTTGCCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAGGATTACGCGGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGGTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGATGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCTGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAATTGACGCGGCTAAGGATTTTTCAGGTCATTTACTAGATTCTAGCGCTAATC
TGTTGACAATTACAGATACTTATTTAGAGTTAGCTCGTCGTGTTGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTGTTTTC
ATTCTATGACCCAGAAGTTATGGCATTGAGTCAGGAAGATTACCAAGCTTTTCTTGCGGAAACACCTGATTTAAAAAGGT
ATCATCATTTCTTTGACAAATTGTTCCAGACACGTGACCATGTGCTCAGCCAGGCTGAAGAGGAATTATTAGCAGGAGCC
CAAGAAATTTTCAACGGCGCTGAAGAAACCTTTAGTATTCTTGATAACGCTGATATTGTCTTTCCAGTAGTTAAAAATGA
TAAGGGGGAAGATGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCATTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGATACCTTGTTAGAAACGGTTAATAAACATTTGCCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAGGATTACGCGGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGGTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGATGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCTGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pepF | Streptococcus salivarius strain HSISS4 |
71.215 |
100 |
0.712 |