Detailed information NTG1141279

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN28_RS06515
• Genome accession: NZ_LS483430
• Coordinates: 1287061..1287786 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC12044
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1282061..1292786

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN28_RS06480 (NCTC12044_01290)	rnpM	1282095..1282391 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQN28_RS06485 (NCTC12044_01291)	nusA	1282407..1283564 (-)	1158	WP_002994325.1	transcription termination factor NusA	-
DQN28_RS06490 (NCTC12044_01292)	rimP	1283739..1284275 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQN28_RS06500 (NCTC12044_01294)	trmB	1284534..1285169 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN28_RS06505 (NCTC12044_01295)	ccrZ	1285169..1285960 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN28_RS06510 (NCTC12044_01296)	-	1286024..1287058 (-)	1035	WP_002988663.1	ABC transporter permease	-
DQN28_RS06515 (NCTC12044_01297)	pptA	1287061..1287786 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN28_RS06520 (NCTC12044_01298)	-	1287858..1288277 (+)	420	WP_002983376.1	HIT family protein	-
DQN28_RS06525 (NCTC12044_01299)	-	1288274..1288630 (+)	357	WP_002988657.1	hypothetical protein	-
DQN28_RS06530 (NCTC12044_01300)	brpA	1288741..1290024 (-)	1284	WP_002994335.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN28_RS06535 (NCTC12044_01301)	-	1290033..1290557 (-)	525	WP_002994338.1	GNAT family N-acetyltransferase	-
DQN28_RS06540 (NCTC12044_01302)	tsaE	1290532..1290993 (-)	462	WP_111686335.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN28_RS06545 (NCTC12044_01303)	-	1291147..1292607 (-)	1461	WP_111686336.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1141279 DQN28_RS06515 WP_002983379.1 1287061..1287786(-) (pptA) [Streptococcus pyogenes strain NCTC12044]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1141279 DQN28_RS06515 WP_002983379.1 1287061..1287786(-) (pptA) [Streptococcus pyogenes strain NCTC12044]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714