Detailed information NTG1141053

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQN31_RS03070
• Genome accession: NZ_LS483421
• Coordinates: 588567..589604 (+)
• Length: 345 a.a.
• NCBI ID: WP_014407697.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10877
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 583567..594604

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN31_RS03045 (NCTC10877_00593)	-	583830..585161 (+)	1332	WP_014407700.1	dipeptidase	-
DQN31_RS03050 (NCTC10877_00594)	arcC	585181..586131 (+)	951	WP_009880962.1	carbamate kinase	-
DQN31_RS03055 (NCTC10877_00595)	asnA	586445..587437 (+)	993	WP_014407699.1	aspartate--ammonia ligase	-
DQN31_RS03060 (NCTC10877_00596)	rsmD	587560..588099 (+)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQN31_RS03065 (NCTC10877_00597)	coaD	588089..588580 (+)	492	WP_014407698.1	pantetheine-phosphate adenylyltransferase	-
DQN31_RS03070 (NCTC10877_00598)	sepM	588567..589604 (+)	1038	WP_014407697.1	SepM family pheromone-processing serine protease	Regulator
DQN31_RS03075 (NCTC10877_00599)	-	590030..591007 (+)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
DQN31_RS03080 (NCTC10877_00600)	-	591455..592075 (+)	621	WP_002992791.1	YutD family protein	-
DQN31_RS03085 (NCTC10877_00601)	rlmN	592079..593158 (+)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQN31_RS03090 (NCTC10877_00602)	-	593240..593866 (-)	627	WP_002983834.1	prepilin peptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37571.33 Da
• Isoelectric Point: 9.6692

>NTDB_id=1141053 DQN31_RS03070 WP_014407697.1 588567..589604(+) (sepM) [Streptococcus pyogenes strain NCTC10877]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGMLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1141053 DQN31_RS03070 WP_014407697.1 588567..589604(+) (sepM) [Streptococcus pyogenes strain NCTC10877]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAATGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGAGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAACGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.275	100	0.693