Detailed information NTG1141048

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN31_RS02235
• Genome accession: NZ_LS483421
• Coordinates: 421996..422721 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC10877
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 416996..427721

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN31_RS02205 (NCTC10877_00432)	-	417175..418635 (+)	1461	WP_002988645.1	NCS2 family permease	-
DQN31_RS02210 (NCTC10877_00433)	tsaE	418789..419250 (+)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN31_RS02215 (NCTC10877_00434)	-	419225..419749 (+)	525	WP_014407786.1	GNAT family N-acetyltransferase	-
DQN31_RS02220 (NCTC10877_00435)	brpA	419758..421041 (+)	1284	WP_014411892.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN31_RS02225 (NCTC10877_00436)	-	421152..421508 (-)	357	WP_014407784.1	hypothetical protein	-
DQN31_RS02230 (NCTC10877_00437)	-	421505..421924 (-)	420	WP_002983376.1	HIT family protein	-
DQN31_RS02235 (NCTC10877_00438)	pptA	421996..422721 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN31_RS02240 (NCTC10877_00439)	-	422724..423758 (+)	1035	WP_002994331.1	ABC transporter permease	-
DQN31_RS02245 (NCTC10877_00440)	ccrZ	423822..424613 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN31_RS02250 (NCTC10877_00441)	trmB	424613..425248 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN31_RS02260 (NCTC10877_00443)	rimP	425507..426043 (+)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQN31_RS02265 (NCTC10877_00444)	nusA	426218..427375 (+)	1158	WP_002988817.1	transcription termination factor NusA	-
DQN31_RS02270 (NCTC10877_00445)	rnpM	427391..427687 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1141048 DQN31_RS02235 WP_002983379.1 421996..422721(+) (pptA) [Streptococcus pyogenes strain NCTC10877]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1141048 DQN31_RS02235 WP_002983379.1 421996..422721(+) (pptA) [Streptococcus pyogenes strain NCTC10877]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714