Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   T303_RS07930 Genome accession   NZ_CP006819
Coordinates   1497998..1499083 (-) Length   361 a.a.
NCBI ID   WP_011226304.1    Uniprot ID   -
Organism   Streptococcus thermophilus ASCC 1275     
Function   internalize XIP (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1481545..1552577 1497998..1499083 within 0


Gene organization within MGE regions


Location: 1481545..1552577
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  T303_RS07855 (T303_07995) liaF 1481553..1482251 (-) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  T303_RS11690 (T303_08000) - 1482506..1482673 (-) 168 WP_014608530.1 potassium channel family protein -
  T303_RS07860 (T303_08005) stkP/pknB 1483311..1485182 (-) 1872 WP_024703938.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  T303_RS07865 (T303_08010) - 1485182..1485919 (-) 738 WP_002946881.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  T303_RS07870 (T303_08015) rsmB 1485963..1487285 (-) 1323 WP_014608533.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  T303_RS07875 (T303_08020) fmt 1487275..1488210 (-) 936 WP_014608534.1 methionyl-tRNA formyltransferase -
  T303_RS07880 (T303_08025) - 1488228..1490624 (-) 2397 WP_024703939.1 primosomal protein N' -
  T303_RS07885 (T303_08030) rpoZ 1490766..1491080 (-) 315 WP_002951415.1 DNA-directed RNA polymerase subunit omega -
  T303_RS07890 (T303_08035) gmk 1491102..1491731 (-) 630 WP_014608537.1 guanylate kinase -
  T303_RS07895 (T303_08040) ftsY 1491957..1493348 (-) 1392 WP_014608538.1 signal recognition particle-docking protein FtsY -
  T303_RS07900 (T303_08045) - 1493362..1494177 (-) 816 WP_011226298.1 Cof-type HAD-IIB family hydrolase -
  T303_RS07905 (T303_08050) - 1494170..1494964 (-) 795 WP_011681412.1 HAD family hydrolase -
  T303_RS07910 (T303_08055) - 1495149..1495526 (+) 378 WP_011681413.1 GntR family transcriptional regulator -
  T303_RS07915 (T303_08060) - 1495531..1496229 (+) 699 WP_023909821.1 ABC transporter ATP-binding protein -
  T303_RS07920 (T303_08065) - 1496241..1497026 (+) 786 WP_002951425.1 hypothetical protein -
  T303_RS07925 (T303_08070) amiF 1497076..1498005 (-) 930 WP_002951426.1 ATP-binding cassette domain-containing protein Regulator
  T303_RS07930 (T303_08075) amiE 1497998..1499083 (-) 1086 WP_011226304.1 ABC transporter ATP-binding protein Regulator
  T303_RS07935 (T303_08080) amiD 1499093..1500019 (-) 927 WP_002946409.1 oligopeptide ABC transporter permease OppC Regulator
  T303_RS07940 (T303_08085) amiC 1500019..1501512 (-) 1494 WP_011681416.1 ABC transporter permease Regulator
  T303_RS07945 (T303_08090) amiA 1501574..1503541 (-) 1968 WP_024703940.1 peptide ABC transporter substrate-binding protein Regulator
  T303_RS07950 (T303_08095) - 1503897..1505074 (+) 1178 Protein_1505 ISL3 family transposase -
  T303_RS07955 (T303_08100) amiA3 1505119..1507092 (-) 1974 WP_011681419.1 peptide ABC transporter substrate-binding protein Regulator
  T303_RS07965 (T303_08110) - 1507397..1508544 (+) 1148 WP_095559415.1 IS3 family transposase -
  T303_RS10555 - 1508582..1508766 (-) 185 Protein_1508 IS3 family transposase -
  T303_RS11695 (T303_08115) - 1508760..1509161 (-) 402 Protein_1509 ABC transporter ATP-binding protein -
  T303_RS07980 (T303_08120) - 1509156..1509516 (-) 361 Protein_1510 TatD family hydrolase -
  T303_RS07985 (T303_08125) - 1509862..1511067 (+) 1206 WP_011681420.1 OFA family MFS transporter -
  T303_RS10560 - 1511113..1512426 (-) 1314 Protein_1512 IS3 family transposase -
  T303_RS08000 (T303_08140) pta 1512551..1513534 (-) 984 WP_011227420.1 phosphate acetyltransferase -
  T303_RS08005 (T303_08145) - 1513548..1514444 (-) 897 WP_024703943.1 RluA family pseudouridine synthase -
  T303_RS08010 (T303_08150) - 1514441..1515277 (-) 837 WP_014608552.1 NAD kinase -
  T303_RS08015 (T303_08155) - 1515249..1515923 (-) 675 WP_011681427.1 GTP pyrophosphokinase family protein -
  T303_RS08020 (T303_08160) - 1516019..1516594 (+) 576 WP_002951444.1 CYTH domain-containing protein -
  T303_RS08025 (T303_08165) - 1516956..1517927 (+) 972 WP_002951446.1 ribose-phosphate diphosphokinase -
  T303_RS08030 (T303_08170) - 1517931..1519043 (+) 1113 WP_014608554.1 cysteine desulfurase family protein -
  T303_RS08035 (T303_08175) - 1519045..1519392 (+) 348 WP_014608555.1 DUF1831 domain-containing protein -
  T303_RS08040 (T303_08180) - 1519536..1520195 (+) 660 WP_024703944.1 redox-sensing transcriptional repressor Rex -
  T303_RS08045 (T303_08185) - 1520188..1520883 (+) 696 WP_024703945.1 gamma-glutamyl-gamma-aminobutyrate hydrolase family protein -
  T303_RS08050 (T303_08190) radC 1520936..1521622 (-) 687 WP_014727630.1 DNA repair protein RadC -
  T303_RS08055 (T303_08195) - 1521671..1523455 (-) 1785 WP_024703946.1 rhamnan synthesis F family protein -
  T303_RS08060 (T303_08200) - 1523452..1524519 (-) 1068 WP_024703947.1 glycosyltransferase -
  T303_RS08065 (T303_08205) - 1524539..1525744 (-) 1206 WP_014727633.1 ABC transporter ATP-binding protein -
  T303_RS08070 (T303_08210) - 1525744..1526553 (-) 810 WP_024703948.1 ABC transporter permease -
  T303_RS08075 (T303_08215) - 1526537..1527493 (-) 957 WP_024703949.1 glycosyltransferase family 2 protein -
  T303_RS08080 (T303_08220) - 1527490..1528638 (-) 1149 WP_024703950.1 glycosyltransferase family 1 protein -
  T303_RS08085 (T303_08225) - 1528745..1530286 (-) 1542 WP_024703951.1 DUF2142 domain-containing protein -
  T303_RS08090 (T303_08230) - 1530293..1531303 (-) 1011 WP_024703952.1 glycosyltransferase -
  T303_RS08095 (T303_08235) - 1531303..1532577 (-) 1275 WP_024703953.1 polysaccharide biosynthesis protein -
  T303_RS08100 (T303_08240) - 1532570..1532902 (-) 333 WP_011226332.1 DUF2304 domain-containing protein -
  T303_RS08105 (T303_08245) - 1532908..1533603 (-) 696 WP_024703954.1 glycosyltransferase family 2 protein -
  T303_RS08110 (T303_08250) rfbD 1533680..1534531 (-) 852 WP_014621820.1 dTDP-4-dehydrorhamnose reductase -
  T303_RS08115 (T303_08255) - 1534608..1535942 (-) 1335 WP_024703955.1 DUF6056 family protein -
  T303_RS08120 (T303_08260) - 1536055..1536981 (-) 927 WP_024703956.1 glycosyltransferase family 2 protein -
  T303_RS08125 (T303_08265) - 1536991..1537326 (-) 336 WP_024703957.1 metal-sulfur cluster assembly factor -
  T303_RS10890 (T303_08270) rpoD 1537380..1538489 (-) 1110 WP_011227440.1 RNA polymerase sigma factor RpoD -
  T303_RS10895 (T303_08275) dnaG 1538493..1540304 (-) 1812 WP_024703958.1 DNA primase -
  T303_RS08140 (T303_08280) mscL 1540444..1540527 (+) 84 Protein_1541 large conductance mechanosensitive channel protein MscL -
  T303_RS08145 (T303_08285) rpsU 1540687..1540863 (-) 177 WP_011681449.1 30S ribosomal protein S21 -
  T303_RS08150 (T303_08290) - 1541057..1541851 (-) 795 WP_023909836.1 ABC transporter substrate-binding protein -
  T303_RS08155 (T303_08295) - 1541913..1543022 (-) 1110 WP_024703959.1 aminotransferase -
  T303_RS08160 (T303_08300) - 1543370..1544167 (-) 798 WP_014621828.1 transporter substrate-binding domain-containing protein -
  T303_RS08165 (T303_08305) - 1544164..1544994 (-) 831 WP_014621829.1 transporter substrate-binding domain-containing protein -
  T303_RS08170 (T303_08310) - 1545208..1545672 (-) 465 WP_011681454.1 8-oxo-dGTP diphosphatase -
  T303_RS08175 (T303_08315) uvrB 1545717..1547708 (-) 1992 WP_014608579.1 excinuclease ABC subunit UvrB -
  T303_RS08180 (T303_08320) - 1547855..1548322 (-) 468 WP_014608580.1 hypothetical protein -
  T303_RS10570 - 1548395..1549331 (-) 937 Protein_1550 type II CAAX endopeptidase family protein -
  T303_RS08195 (T303_08335) - 1549530..1551740 (+) 2211 WP_014727645.1 ABC transporter substrate-binding protein/permease -
  T303_RS08200 (T303_08340) - 1551740..1552480 (+) 741 WP_024703961.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 39864.62 Da        Isoelectric Point: 4.7435

>NTDB_id=114103 T303_RS07930 WP_011226304.1 1497998..1499083(-) (amiE) [Streptococcus thermophilus ASCC 1275]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=114103 T303_RS07930 WP_011226304.1 1497998..1499083(-) (amiE) [Streptococcus thermophilus ASCC 1275]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-300)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus thermophilus LMG 18311

100

100

1
  amiE Streptococcus thermophilus LMD-9

100

100

1
  amiE Streptococcus salivarius strain HSISS4

96.953

100

0.97
  oppD Streptococcus mutans UA159

54.441

96.676

0.526

Multiple sequence alignment