Detailed information NTG1140996

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN75_RS02205
• Genome accession: NZ_LS483420
• Coordinates: 418211..418936 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13739
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 413211..423936

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN75_RS02175 (NCTC13739_00432)	-	413391..414851 (+)	1461	WP_012560892.1	NCS2 family permease	-
DQN75_RS02180 (NCTC13739_00433)	tsaE	415004..415465 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN75_RS02185 (NCTC13739_00434)	-	415440..415964 (+)	525	WP_063811834.1	GNAT family N-acetyltransferase	-
DQN75_RS02190 (NCTC13739_00435)	brpA	415973..417256 (+)	1284	WP_014411892.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN75_RS02195 (NCTC13739_00436)	-	417367..417723 (-)	357	WP_014407784.1	hypothetical protein	-
DQN75_RS02200 (NCTC13739_00437)	-	417720..418139 (-)	420	WP_002983376.1	HIT family protein	-
DQN75_RS02205 (NCTC13739_00438)	pptA	418211..418936 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN75_RS02210 (NCTC13739_00439)	-	418939..419973 (+)	1035	WP_111684628.1	ABC transporter permease	-
DQN75_RS02215 (NCTC13739_00440)	ccrZ	420037..420828 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN75_RS02220 (NCTC13739_00441)	trmB	420828..421463 (+)	636	WP_111684630.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN75_RS02230 (NCTC13739_00443)	rimP	421722..422258 (+)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQN75_RS02235 (NCTC13739_00444)	nusA	422433..423590 (+)	1158	WP_002988817.1	transcription termination factor NusA	-
DQN75_RS02240 (NCTC13739_00445)	rnpM	423606..423902 (+)	297	WP_111684632.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140996 DQN75_RS02205 WP_002983379.1 418211..418936(+) (pptA) [Streptococcus pyogenes strain NCTC13739]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140996 DQN75_RS02205 WP_002983379.1 418211..418936(+) (pptA) [Streptococcus pyogenes strain NCTC13739]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714