Detailed information NTG1140964

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM62_RS07485
• Genome accession: NZ_LS483418
• Coordinates: 1483734..1484783 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain NCTC10234
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1478734..1489783

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM62_RS07465 (NCTC10234_01464)	nadE	1479140..1479964 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
DQM62_RS07470 (NCTC10234_01466)	-	1481260..1481787 (-)	528	WP_012027591.1	VanZ family protein	-
DQM62_RS07475 (NCTC10234_01467)	rlmN	1481784..1482896 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM62_RS07480 (NCTC10234_01468)	-	1482905..1483546 (-)	642	WP_012027595.1	YutD family protein	-
DQM62_RS07485 (NCTC10234_01469)	sepM	1483734..1484783 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
DQM62_RS07490 (NCTC10234_01470)	coaD	1484770..1485258 (-)	489	WP_014917298.1	pantetheine-phosphate adenylyltransferase	-
DQM62_RS07495 (NCTC10234_01471)	rsmD	1485248..1485787 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM62_RS07500 (NCTC10234_01472)	-	1486095..1486817 (-)	723	WP_012027598.1	lipoprotein	-
DQM62_RS07505 (NCTC10234_01473)	-	1486874..1487260 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
DQM62_RS07510 (NCTC10234_01474)	-	1487260..1487478 (-)	219	WP_004194736.1	YqgQ family protein	-
DQM62_RS07515 (NCTC10234_01475)	-	1487786..1488388 (-)	603	WP_012027601.1	response regulator transcription factor	-
DQM62_RS07520 (NCTC10234_01476)	-	1488385..1489479 (-)	1095	WP_024383662.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=1140964 DQM62_RS07485 WP_012775295.1 1483734..1484783(-) (sepM) [Streptococcus suis strain NCTC10234]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=1140964 DQM62_RS07485 WP_012775295.1 1483734..1484783(-) (sepM) [Streptococcus suis strain NCTC10234]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605