Detailed information NTG1140753

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN44_RS02220
• Genome accession: NZ_LS483414
• Coordinates: 422096..422821 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13736
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 417096..427821

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN44_RS02190 (NCTC13736_00430)	-	417276..418736 (+)	1461	WP_002988645.1	NCS2 family permease	-
DQN44_RS02195 (NCTC13736_00431)	tsaE	418890..419351 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN44_RS02200 (NCTC13736_00432)	-	419326..419850 (+)	525	WP_002988650.1	GNAT family N-acetyltransferase	-
DQN44_RS02205 (NCTC13736_00433)	brpA	419859..421139 (+)	1281	WP_002988654.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN44_RS02210 (NCTC13736_00434)	-	421252..421608 (-)	357	WP_002988657.1	hypothetical protein	-
DQN44_RS02215 (NCTC13736_00435)	-	421605..422024 (-)	420	WP_002988659.1	HIT family protein	-
DQN44_RS02220 (NCTC13736_00436)	pptA	422096..422821 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN44_RS02225 (NCTC13736_00437)	-	422824..423858 (+)	1035	WP_030127300.1	ABC transporter permease	-
DQN44_RS02230 (NCTC13736_00438)	ccrZ	423922..424713 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN44_RS02235 (NCTC13736_00439)	trmB	424713..425348 (+)	636	WP_011184863.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN44_RS02245 (NCTC13736_00441)	rimP	425608..426144 (+)	537	WP_030127299.1	ribosome maturation factor RimP	-
DQN44_RS02250 (NCTC13736_00442)	nusA	426319..427476 (+)	1158	WP_002988817.1	transcription termination factor NusA	-
DQN44_RS02255 (NCTC13736_00443)	rnpM	427492..427788 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140753 DQN44_RS02220 WP_002983379.1 422096..422821(+) (pptA) [Streptococcus pyogenes strain NCTC13736]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140753 DQN44_RS02220 WP_002983379.1 422096..422821(+) (pptA) [Streptococcus pyogenes strain NCTC13736]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714