Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   DQN24_RS02940 Genome accession   NZ_LS483411
Coordinates   583183..583692 (-) Length   169 a.a.
NCBI ID   WP_111695366.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC11426     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 578183..588692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN24_RS02910 (NCTC11426_00577) nfuA 578846..579442 (-) 597 WP_021034385.1 Fe-S biogenesis protein NfuA -
  DQN24_RS02915 (NCTC11426_00578) - 579518..580204 (-) 687 WP_021034384.1 ComF family protein -
  DQN24_RS02920 (NCTC11426_00579) tnpA 580452..580905 (-) 454 Protein_556 IS200/IS605 family transposase -
  DQN24_RS02925 (NCTC11426_00580) comE 580902..582245 (-) 1344 WP_021034382.1 type IV pilus secretin PilQ Machinery gene
  DQN24_RS02930 (NCTC11426_00581) comD 582255..582668 (-) 414 WP_021034381.1 pilus assembly protein PilP Machinery gene
  DQN24_RS02935 (NCTC11426_00582) comC 582665..583186 (-) 522 WP_111695365.1 competence protein C Machinery gene
  DQN24_RS02940 (NCTC11426_00583) comB 583183..583692 (-) 510 WP_111695366.1 competence protein B Machinery gene
  DQN24_RS02945 (NCTC11426_00584) comA 583693..584490 (-) 798 WP_110430714.1 pilus assembly protein PilM Machinery gene
  DQN24_RS02950 (NCTC11426_00585) - 584589..587183 (+) 2595 WP_110430713.1 penicillin-binding protein 1A -
  DQN24_RS02955 (NCTC11426_00586) - 587260..588105 (+) 846 WP_111695367.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  DQN24_RS02960 (NCTC11426_00587) - 588247..588576 (+) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -

Sequence

Protein


Download         Length: 169 a.a.        Molecular weight: 19955.96 Da        Isoelectric Point: 9.3352

>NTDB_id=1140658 DQN24_RS02940 WP_111695366.1 583183..583692(-) (comB) [Haemophilus influenzae strain NCTC11426]
MSMNLLPWRTYQHQNRLRRLAFYIALFILLAINLTLAFSNLIEQQKQHLQAQQTSFEQLNQQLYKTAKKIEQLRSAVQVG
EILTSIPKEQVKKSLQLLSELPFQQGELNKFKQDAHNLSLEGLAQDQREFELIHQFLKKHFPNVKLSQFQPEQQSLYFLF
DVEQVGEDK

Nucleotide


Download         Length: 510 bp        

>NTDB_id=1140658 DQN24_RS02940 WP_111695366.1 583183..583692(-) (comB) [Haemophilus influenzae strain NCTC11426]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAACCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAACTTTGGCTTTTAGTAATTTAATTGAACAACAGAAACAACATTTGCAGGCGCAACAAA
CATCTTTTGAACAACTTAATCAGCAACTTTATAAAACCGCCAAGAAAATTGAACAGTTGCGTAGTGCAGTGCAGGTTGGC
GAAATTTTGACATCTATTCCTAAAGAGCAAGTAAAAAAGAGTTTACAGCTGCTAAGTGAATTACCTTTTCAGCAAGGAGA
ACTGAATAAATTTAAACAAGATGCTCATAACTTAAGTTTGGAAGGTCTCGCACAAGATCAAAGAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGCCAGTTTCAACCTGAACAACAGTCATTGTATTTTCTCTTT
GATGTGGAACAAGTTGGAGAAGATAAGTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae 86-028NP

86.826

98.817

0.858
  comB Haemophilus influenzae Rd KW20

85.629

98.817

0.846

Multiple sequence alignment