Detailed information NTG1140555

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQN21_RS03325
• Genome accession: NZ_LS483409
• Coordinates: 597888..598973 (+)
• Length: 361 a.a.
• NCBI ID: WP_009853602.1
• Uniprot ID: A0A060RJA1
• Organism: Streptococcus gallolyticus strain NCTC13773
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 592888..603973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN21_RS03300 (NCTC13773_00664)	asnA	593820..594812 (+)	993	WP_009853597.1	aspartate--ammonia ligase	-
DQN21_RS03305 (NCTC13773_00665)	-	594941..595693 (-)	753	WP_077496393.1	hypothetical protein	-
DQN21_RS03310 (NCTC13773_00666)	-	595865..596707 (-)	843	WP_077496395.1	hypothetical protein	-
DQN21_RS03315 (NCTC13773_00667)	rsmD	596841..597380 (+)	540	WP_077497997.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQN21_RS03320 (NCTC13773_00668)	coaD	597413..597910 (+)	498	WP_077496397.1	pantetheine-phosphate adenylyltransferase	-
DQN21_RS03325 (NCTC13773_00669)	sepM	597888..598973 (+)	1086	WP_009853602.1	SepM family pheromone-processing serine protease	Regulator
DQN21_RS03330 (NCTC13773_00670)	-	599102..599356 (+)	255	WP_009853603.1	DUF3923 family protein	-
DQN21_RS03335 (NCTC13773_00671)	-	599540..600199 (+)	660	WP_077496399.1	MIP/aquaporin family protein	-
DQN21_RS03340 (NCTC13773_00672)	-	600338..600847 (+)	510	WP_077496401.1	hypothetical protein	-
DQN21_RS03345 (NCTC13773_00673)	-	600959..602284 (+)	1326	WP_077496403.1	bifunctional metallophosphatase/5'-nucleotidase	-
DQN21_RS03350 (NCTC13773_00674)	-	602316..602894 (+)	579	WP_077496404.1	YutD family protein	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39104.76 Da
• Isoelectric Point: 4.0512

>NTDB_id=1140555 DQN21_RS03325 WP_009853602.1 597888..598973(+) (sepM) [Streptococcus gallolyticus strain NCTC13773]
MAILKRFKEILKKLGRILYRFKWWILGVVGIVFLLFSLLYPLDYYIEMPGGAYDIRSVLTVDNKEDDEDGSYNFVAVTVS
QATLAQLVYAWLTPYTEISTAADVTGGYSNADYLRINEYYMETSQNTATYQALTLAGKEATLDYQGVYVLNVSDNSTFKG
ILNIADTVTGVNGQTFNSSAELMAYVADLDLGSEVTVQYTSDGEAKEATGKIIELSNGKNGIGIGLVDHTSVSSDVDVDF
DTSGVGGPSAGLMFTLDIYDQLNSEDLRKGRKIAGTGTIESDGSVGDIGGAALKVVAAAKAGADIFFVPNNPVDEETLKK
DPDAKTNYEEAVEAAKDLDTDMKIVPVTTVQEAIDYLRNND

Nucleotide

• Length: 1086 bp

>NTDB_id=1140555 DQN21_RS03325 WP_009853602.1 597888..598973(+) (sepM) [Streptococcus gallolyticus strain NCTC13773]
ATGGCAATCTTAAAAAGATTTAAAGAGATTTTGAAAAAGTTGGGTCGTATTTTATATCGCTTTAAGTGGTGGATATTAGG
TGTTGTAGGCATTGTTTTTTTACTATTTAGCTTGTTGTATCCGCTTGATTACTATATTGAAATGCCTGGTGGTGCTTATG
ATATTCGTAGCGTTTTAACGGTTGATAATAAGGAAGATGACGAAGATGGCTCTTATAATTTTGTGGCTGTCACGGTTAGT
CAGGCGACCTTGGCACAATTGGTTTATGCTTGGTTAACTCCCTACACAGAAATTTCGACAGCCGCAGATGTGACTGGTGG
TTATAGCAATGCTGATTATCTTCGTATCAATGAGTATTACATGGAAACCTCTCAAAATACAGCGACTTATCAAGCCTTAA
CCTTGGCAGGAAAGGAAGCGACGCTTGATTATCAAGGGGTTTATGTTTTAAATGTTAGTGATAATTCGACGTTTAAAGGG
ATTTTGAATATCGCTGATACGGTAACTGGGGTTAACGGTCAGACATTTAACAGCTCGGCAGAATTAATGGCCTATGTGGC
TGATTTGGATTTAGGGTCTGAGGTAACAGTTCAATATACATCAGACGGCGAAGCAAAAGAAGCCACAGGAAAAATTATTG
AATTGTCAAATGGAAAAAATGGTATCGGAATCGGTTTGGTAGATCATACGTCGGTGTCATCAGATGTTGATGTTGATTTT
GATACGAGTGGTGTCGGTGGTCCAAGTGCTGGTTTGATGTTTACGCTTGATATTTATGACCAATTAAATAGTGAAGATTT
GCGTAAAGGTCGTAAAATTGCTGGTACAGGTACGATTGAATCAGATGGTTCAGTCGGGGATATTGGTGGCGCAGCACTTA
AAGTTGTTGCTGCTGCTAAAGCTGGTGCGGATATTTTCTTTGTTCCAAATAACCCTGTGGATGAGGAAACATTGAAAAAA
GATCCTGATGCAAAAACGAACTATGAAGAAGCTGTCGAAGCTGCTAAAGACCTCGATACCGATATGAAAATCGTCCCAGT
AACAACCGTCCAAGAAGCAATTGACTATCTACGAAACAATGATTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (246-323)

• PDZ domain (PDZ_2) (145-209)

3D structure

• AlphaFold DB: A0A060RJA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.035	94.46	0.643