Detailed information NTG1140527

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DQN33_RS09500
• Genome accession: NZ_LS483408
• Coordinates: 1903348..1905789 (-)
• Length: 813 a.a.
• NCBI ID: WP_046389727.1
• Uniprot ID: -
• Organism: Streptococcus uberis strain NCTC4674
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1898348..1910789

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN33_RS09490 (NCTC4674_01998)	groL	1901245..1902873 (-)	1629	WP_046388382.1	chaperonin GroEL	-
DQN33_RS09495 (NCTC4674_01999)	groES	1902919..1903206 (-)	288	WP_015912033.1	co-chaperone GroES	-
DQN33_RS09500 (NCTC4674_02000)	clpC	1903348..1905789 (-)	2442	WP_046389727.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQN33_RS09505 (NCTC4674_02001)	-	1905789..1906250 (-)	462	WP_015912035.1	CtsR family transcriptional regulator	-
DQN33_RS09510 (NCTC4674_02002)	-	1906464..1906667 (-)	204	WP_015912036.1	cold-shock protein	-
DQN33_RS09515 (NCTC4674_02003)	-	1906955..1907224 (+)	270	WP_046388882.1	hypothetical protein	-
DQN33_RS09520 (NCTC4674_02004)	-	1907226..1909295 (+)	2070	WP_111673566.1	cation:proton antiporter	-
DQN33_RS09530 (NCTC4674_02006)	ahpC	1909766..1910329 (+)	564	WP_015912043.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90422.99 Da
• Isoelectric Point: 6.5280

>NTDB_id=1140527 DQN33_RS09500 WP_046389727.1 1903348..1905789(-) (clpC) [Streptococcus uberis strain NCTC4674]
MTDYSLKMQAIFKQAQYQAARFDSPYLETWHLLLAMVVVNNSLAGLVFNEFENKIALEEYEAAAILAIGKAPNDDIKEFE
YKGQSKTLSHILSFADAIRNVTHANEVGSEHVLFAILLNPDIMATRLLELAGFKIKDDGKGDLKLADLRKAIEIQAAYSK
ETIKAIYELRKPKKAKTGGTFSDMMKPAGTAGELSDYTRDLTEMASQGLLEPVIGREKEITRMVQVLSRKTKNNPVLVGE
AGVGKTALAYGLAQRIVTGEIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGHIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFSKVLIEEPSIEDAYKILSGLKKSYESYHNVTISD
QAIKTAVKVAHRYLTSKHLPDSAIDLLDEASATVQSFVKKEAPAFITPIDQAIIKGDFKTVSQLLKASKAKPQKPTPVTE
EDIMSTLSKLSGIPLEKISKADSQKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGQLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDINHDHSAMEKRILEELKKTYRPEFINRIDEKVVFHS
LSQEDMRQVVAIMVQPLIKNLEEKGITLKIQPSALKYLSEVGYDVEMGARPLRRTIQTEIEDKLSEFILSGQLKTGKTLK
IGMSQGKLKFDMV

Nucleotide

• Length: 2442 bp

>NTDB_id=1140527 DQN33_RS09500 WP_046389727.1 1903348..1905789(-) (clpC) [Streptococcus uberis strain NCTC4674]
ATGACAGATTATTCACTCAAAATGCAAGCTATTTTTAAACAAGCACAATACCAAGCGGCGCGTTTTGATAGCCCCTATTT
AGAAACTTGGCACCTCTTATTGGCAATGGTTGTTGTTAATAATTCACTAGCTGGCCTTGTTTTTAATGAATTTGAAAATA
AGATTGCCTTGGAAGAATATGAAGCGGCAGCTATCTTAGCCATTGGCAAAGCTCCAAATGATGATATTAAGGAGTTTGAA
TATAAAGGTCAGTCAAAAACACTTTCTCATATTTTGTCCTTTGCTGATGCTATTCGAAATGTTACACATGCCAATGAAGT
AGGATCAGAGCATGTTCTTTTTGCTATCTTATTAAATCCTGATATTATGGCAACTCGTTTGCTAGAATTAGCTGGATTTA
AAATCAAAGATGATGGCAAAGGCGATTTGAAATTGGCTGATTTAAGAAAAGCCATTGAAATTCAAGCTGCTTATAGTAAA
GAAACCATTAAAGCTATCTACGAACTCAGAAAACCCAAAAAAGCCAAAACAGGCGGTACTTTCTCAGATATGATGAAACC
AGCTGGCACTGCGGGAGAATTATCAGATTATACGAGAGATTTGACAGAAATGGCAAGTCAAGGCTTACTTGAGCCTGTTA
TTGGCAGAGAAAAAGAAATCACTCGAATGGTTCAAGTCTTAAGTCGTAAAACGAAAAATAATCCAGTTTTAGTCGGTGAG
GCTGGTGTTGGTAAGACAGCATTGGCCTATGGCTTAGCCCAACGGATTGTGACTGGTGAGATTCCATACGAACTTCGTGA
TATGCGTGTCTTAGAATTAGACATGATGAGTGTGGTGGCAGGTACGCGTTTTCGTGGTGATTTTGAAGAACGCATGAATC
AAATTATTGATGATATTGAAAGTGACGGTCATATCATTCTCTTTGTCGATGAATTACACACTATTATGGGATCTGGCAGT
GGTATTGATAGCACTTTAGATGCTGCAAATATCCTCAAACCAGCTCTCTCAAGAGGAACCCTACATATGGTTGGGGCAAC
TACTCAAGAAGAGTATCAAAAACATATTGAAAAAGATGCCGCTTTATCTCGTCGTTTCTCAAAAGTTTTGATTGAAGAAC
CAAGTATAGAGGATGCCTACAAGATACTATCAGGGTTGAAAAAATCTTACGAAAGCTATCATAATGTCACCATCTCAGAT
CAAGCCATCAAAACAGCAGTCAAAGTTGCTCATCGCTATTTGACGAGCAAGCACTTACCTGATTCTGCGATTGATTTATT
AGATGAAGCTAGCGCAACGGTTCAAAGTTTCGTCAAAAAAGAGGCGCCAGCCTTCATCACACCAATTGACCAAGCCATCA
TAAAAGGTGATTTTAAAACAGTTAGCCAACTTTTGAAAGCTTCCAAGGCTAAGCCCCAGAAACCAACTCCTGTTACTGAA
GAAGATATCATGTCTACATTAAGTAAATTGTCAGGAATTCCACTGGAAAAAATTAGCAAGGCAGATAGTCAGAAATACCT
TAACCTGGAAAAAGAATTACATAAGCGTGTTATCGGTCAAGAGGATGCAGTCTCAGCAATTTCAAGAGCTATCAGACGCA
ATCAGTCTGGTATTCGAACAGGTAAACGTCCAATTGGCTCCTTTATGTTCCTTGGACCGACAGGTGTTGGGAAAACAGAA
TTAGCAAAAGCTTTAGCAGAACTCTTATTCGATGATGAATCAGCTCTCATTCGTTTTGATATGTCAGAATACATGGAAAA
ATTCGCTGCTAGCCGTTTAAATGGAGCACCTCCAGGATATGTTGGCTATGACGAGGGCGGTGAGTTGACCGAAAAAGTAC
GTAACAAACCCTATTCTGTTCTTCTCTTCGATGAAGTTGAAAAAGCCCATCCAGATATCTTTAACGTTTTGTTACAAGTC
TTGGATGATGGACAATTAACGGATTCTCGTGGGCGAAAAGTCGATTTTTCAAATACAATCATTATCATGACAAGTAATTT
AGGTGCTACAGCGCTTCGAGATGATAAAACGGTTGGATTTGGTGCTAAAGATATCAACCATGATCATTCGGCCATGGAAA
AACGCATCTTAGAAGAATTGAAAAAAACCTACCGACCAGAATTTATCAACCGAATTGATGAAAAAGTTGTCTTCCATAGC
TTAAGTCAAGAAGACATGCGACAAGTTGTCGCGATTATGGTTCAACCCTTGATTAAGAACTTGGAAGAAAAAGGGATTAC
CCTCAAAATACAACCATCTGCATTAAAATATTTGTCTGAAGTCGGTTATGATGTTGAGATGGGGGCAAGACCACTAAGAC
GAACCATCCAAACAGAAATCGAAGACAAGTTGTCAGAATTCATTTTATCTGGTCAACTTAAAACTGGTAAGACTTTAAAA
ATTGGTATGAGCCAAGGTAAATTAAAATTTGATATGGTCTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (104-136)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-51)

• AAA lid domain (AAA_lid_9) (375-451)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.816	100	0.749
clpC	Streptococcus thermophilus LMG 18311	71.795	100	0.723
clpC	Streptococcus thermophilus LMD-9	71.673	100	0.722
clpC	Streptococcus pneumoniae TIGR4	65.148	99.877	0.651
clpC	Streptococcus pneumoniae Rx1	65.025	99.877	0.649
clpC	Streptococcus pneumoniae D39	65.025	99.877	0.649
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	50.06	100	0.513
clpC	Bacillus subtilis subsp. subtilis str. 168	43.943	100	0.455