Detailed information NTG1140469

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM86_RS06845
• Genome accession: NZ_LS483407
• Coordinates: 1337853..1338578 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13744
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1332853..1343578

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM86_RS06810 (NCTC13744_01354)	rnpM	1332887..1333183 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQM86_RS06815 (NCTC13744_01355)	nusA	1333199..1334356 (-)	1158	WP_002988817.1	transcription termination factor NusA	-
DQM86_RS06820 (NCTC13744_01356)	rimP	1334531..1335067 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQM86_RS06830 (NCTC13744_01358)	trmB	1335326..1335961 (-)	636	WP_011184863.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM86_RS06835 (NCTC13744_01359)	ccrZ	1335961..1336752 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM86_RS06840 (NCTC13744_01360)	-	1336816..1337850 (-)	1035	WP_002994331.1	ABC transporter permease	-
DQM86_RS06845 (NCTC13744_01361)	pptA	1337853..1338578 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM86_RS06850 (NCTC13744_01362)	-	1338650..1339069 (+)	420	WP_002983376.1	HIT family protein	-
DQM86_RS06855 (NCTC13744_01363)	-	1339066..1339422 (+)	357	WP_047235695.1	hypothetical protein	-
DQM86_RS06860 (NCTC13744_01364)	brpA	1339533..1340816 (-)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM86_RS06865 (NCTC13744_01365)	-	1340825..1341349 (-)	525	WP_020905405.1	GNAT family N-acetyltransferase	-
DQM86_RS06870 (NCTC13744_01366)	tsaE	1341324..1341785 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM86_RS06875 (NCTC13744_01367)	-	1341939..1343399 (-)	1461	WP_012560892.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140469 DQM86_RS06845 WP_002983379.1 1337853..1338578(-) (pptA) [Streptococcus pyogenes strain NCTC13744]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140469 DQM86_RS06845 WP_002983379.1 1337853..1338578(-) (pptA) [Streptococcus pyogenes strain NCTC13744]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714