Detailed information NTG1140303

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM79_RS07085
• Genome accession: NZ_LS483401
• Coordinates: 1380766..1381491 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC10085
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1375766..1386491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM79_RS07050 (NCTC10085_01395)	-	1375900..1376283 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
DQM79_RS07055 (NCTC10085_01396)	-	1376294..1376845 (+)	552	WP_002988670.1	hypothetical protein	-
DQM79_RS07060 (NCTC10085_01397)	-	1376962..1378041 (+)	1080	WP_002988667.1	site-specific integrase	-
DQM79_RS07070 (NCTC10085_01399)	trmB	1378239..1378874 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM79_RS07075 (NCTC10085_01400)	ccrZ	1378874..1379665 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM79_RS07080 (NCTC10085_01401)	-	1379729..1380763 (-)	1035	WP_002988663.1	ABC transporter permease	-
DQM79_RS07085 (NCTC10085_01402)	pptA	1380766..1381491 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM79_RS07090 (NCTC10085_01403)	-	1381563..1381982 (+)	420	WP_002988659.1	HIT family protein	-
DQM79_RS07095 (NCTC10085_01404)	-	1381979..1382335 (+)	357	WP_002988657.1	hypothetical protein	-
DQM79_RS07100 (NCTC10085_01405)	brpA	1382446..1383726 (-)	1281	WP_002988654.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM79_RS07105 (NCTC10085_01406)	-	1383735..1384259 (-)	525	WP_002988650.1	GNAT family N-acetyltransferase	-
DQM79_RS07110 (NCTC10085_01407)	tsaE	1384234..1384695 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM79_RS07115 (NCTC10085_01408)	-	1384849..1386309 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140303 DQM79_RS07085 WP_002983379.1 1380766..1381491(-) (pptA) [Streptococcus pyogenes strain NCTC10085]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140303 DQM79_RS07085 WP_002983379.1 1380766..1381491(-) (pptA) [Streptococcus pyogenes strain NCTC10085]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714