Detailed information
Bioinformatically predicted
Overview
| Name | pepF | Type | Regulator |
| Locus tag | DQM79_RS05635 | Genome accession | NZ_LS483401 |
| Coordinates | 1098637..1100442 (-) | Length | 601 a.a. |
| NCBI ID | WP_002989205.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain NCTC10085 | ||
| Function | degradation of XIP; competence shut-off (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1078396..1125433 | 1098637..1100442 | within | 0 |
Gene organization within MGE regions
Location: 1078396..1125433
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQM79_RS05555 (NCTC10085_01093) | - | 1078434..1079708 (-) | 1275 | WP_002989251.1 | polysaccharide deacetylase family protein | - |
| DQM79_RS05560 (NCTC10085_01094) | - | 1079804..1081231 (-) | 1428 | WP_002989248.1 | NADP-dependent glyceraldehyde-3-phosphate dehydrogenase | - |
| DQM79_RS05565 (NCTC10085_01095) | ptsP | 1081416..1083149 (-) | 1734 | WP_002989245.1 | phosphoenolpyruvate--protein phosphotransferase | - |
| DQM79_RS05570 (NCTC10085_01096) | - | 1083154..1083417 (-) | 264 | WP_002984031.1 | phosphocarrier protein HPr | - |
| DQM79_RS05575 (NCTC10085_01097) | - | 1083810..1084028 (+) | 219 | WP_002989242.1 | redoxin NrdH | - |
| DQM79_RS05580 (NCTC10085_01098) | nrdE | 1084048..1086207 (+) | 2160 | WP_002989239.1 | class 1b ribonucleoside-diphosphate reductase subunit alpha | - |
| DQM79_RS05585 (NCTC10085_01100) | nrdF | 1086529..1087488 (+) | 960 | WP_002987365.1 | class 1b ribonucleoside-diphosphate reductase subunit beta | - |
| DQM79_RS05590 (NCTC10085_01101) | - | 1087550..1088776 (+) | 1227 | WP_370659244.1 | chloride channel protein | - |
| DQM79_RS05595 | - | 1088872..1090028 (+) | 1157 | Protein_1032 | IS3 family transposase | - |
| DQM79_RS05600 (NCTC10085_01105) | - | 1090122..1090817 (-) | 696 | WP_002989227.1 | CPBP family intramembrane glutamic endopeptidase | - |
| DQM79_RS05605 (NCTC10085_01106) | - | 1090836..1091597 (-) | 762 | WP_002995753.1 | DUF3169 family protein | - |
| DQM79_RS05610 (NCTC10085_01107) | - | 1091594..1091809 (-) | 216 | WP_002989220.1 | helix-turn-helix transcriptional regulator | - |
| DQM79_RS05615 (NCTC10085_01108) | alaS | 1092169..1094787 (-) | 2619 | WP_002989217.1 | alanine--tRNA ligase | - |
| DQM79_RS05620 (NCTC10085_01110) | prsA | 1095174..1096229 (-) | 1056 | WP_002984003.1 | peptidylprolyl isomerase PrsA | - |
| DQM79_RS05625 (NCTC10085_01111) | - | 1096292..1096999 (-) | 708 | WP_002989211.1 | O-methyltransferase | - |
| DQM79_RS05630 (NCTC10085_01112) | - | 1097065..1098261 (-) | 1197 | WP_002989208.1 | OFA family MFS transporter | - |
| DQM79_RS05635 (NCTC10085_01113) | pepF | 1098637..1100442 (-) | 1806 | WP_002989205.1 | oligoendopeptidase F | Regulator |
| DQM79_RS05640 (NCTC10085_01114) | - | 1100455..1101417 (-) | 963 | WP_002989200.1 | competence protein CoiA | - |
| DQM79_RS05645 (NCTC10085_01115) | - | 1101712..1102428 (-) | 717 | WP_002989197.1 | pseudouridine synthase | - |
| DQM79_RS05650 (NCTC10085_01116) | nagB | 1102547..1103251 (-) | 705 | WP_002989194.1 | glucosamine-6-phosphate deaminase | - |
| DQM79_RS05655 (NCTC10085_01117) | queA | 1103453..1104481 (+) | 1029 | WP_011284937.1 | tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA | - |
| DQM79_RS05660 (NCTC10085_01118) | - | 1104488..1105708 (+) | 1221 | WP_002989189.1 | DUF3114 domain-containing protein | - |
| DQM79_RS05665 (NCTC10085_01119) | - | 1105822..1106412 (-) | 591 | WP_002989185.1 | serine hydrolase | - |
| DQM79_RS05670 (NCTC10085_01120) | - | 1106409..1106657 (-) | 249 | WP_002989183.1 | serine hydrolase | - |
| DQM79_RS05675 (NCTC10085_01121) | - | 1106713..1106868 (-) | 156 | WP_002989180.1 | hypothetical protein | - |
| DQM79_RS05680 (NCTC10085_01122) | sodA | 1107035..1107640 (-) | 606 | WP_002983977.1 | superoxide dismutase SodA | - |
| DQM79_RS05685 (NCTC10085_01123) | holA | 1107737..1108777 (-) | 1041 | WP_002989176.1 | DNA polymerase III subunit delta | - |
| DQM79_RS05690 (NCTC10085_01124) | - | 1108848..1111091 (-) | 2244 | WP_002989173.1 | DNA internalization-related competence protein ComEC/Rec2 | - |
| DQM79_RS05695 (NCTC10085_01125) | - | 1111072..1111734 (-) | 663 | WP_002983967.1 | ComEA family DNA-binding protein | - |
| DQM79_RS05700 (NCTC10085_01126) | - | 1111934..1112674 (-) | 741 | WP_002989170.1 | lysophospholipid acyltransferase family protein | - |
| DQM79_RS05705 (NCTC10085_01127) | - | 1112792..1113568 (+) | 777 | WP_023612510.1 | tRNA1(Val) (adenine(37)-N6)-methyltransferase | - |
| DQM79_RS05710 (NCTC10085_01128) | - | 1113558..1113836 (+) | 279 | WP_002989164.1 | GIY-YIG nuclease family protein | - |
| DQM79_RS05715 (NCTC10085_01129) | - | 1113860..1115860 (-) | 2001 | WP_002994363.1 | potassium transporter Kup | - |
| DQM79_RS05720 (NCTC10085_01130) | - | 1115987..1117606 (-) | 1620 | WP_002989158.1 | DEAD/DEAH box helicase | - |
| DQM79_RS05725 (NCTC10085_01131) | - | 1117913..1119457 (-) | 1545 | WP_002989155.1 | peptide chain release factor 3 | - |
| DQM79_RS05735 (NCTC10085_01132) | - | 1119705..1120400 (-) | 696 | WP_002989150.1 | TIGR02206 family membrane protein | - |
| DQM79_RS05740 (NCTC10085_01133) | - | 1120481..1121872 (-) | 1392 | WP_002989148.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
| DQM79_RS05745 (NCTC10085_01134) | - | 1122071..1123117 (-) | 1047 | WP_002989146.1 | D-alanine--D-alanine ligase | - |
| DQM79_RS05750 (NCTC10085_01135) | recR | 1123218..1123814 (-) | 597 | WP_002983939.1 | recombination mediator RecR | - |
| DQM79_RS09400 | - | 1123861..1124043 (-) | 183 | WP_011527680.1 | penicillin-binding protein | - |
| DQM79_RS05760 (NCTC10085_01136) | - | 1124602..1125381 (-) | 780 | WP_002989141.1 | formate/nitrite transporter family protein | - |
Sequence
Protein
Download Length: 601 a.a. Molecular weight: 69357.19 Da Isoelectric Point: 4.7093
>NTDB_id=1140294 DQM79_RS05635 WP_002989205.1 1098637..1100442(-) (pepF) [Streptococcus pyogenes strain NCTC10085]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFSGHLLDSSANLLTITDTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMTKGDYLEAAFKVFDERLTELEVLVSKGIHKS
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEIDAAKDFSGHLLDSSANLLTITDTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMTKGDYLEAAFKVFDERLTELEVLVSKGIHKS
Nucleotide
Download Length: 1806 bp
>NTDB_id=1140294 DQM79_RS05635 WP_002989205.1 1098637..1100442(-) (pepF) [Streptococcus pyogenes strain NCTC10085]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAATTGACGCGGCTAAGGATTTTTCAGGTCATTTACTAGATTCTAGCGCTAATC
TGTTGACAATTACAGATACTTATTTAGAGTTAGCTCGTCGTGTTGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTGTTTTC
ATTCTATGACCCAGAAGTTATGGCATTGAGTCAGGAAGATTACCAAGCTTTTCTTGCGGAAACACCTGATTTAAAAAGGT
ATCATCATTTCTTTGACAAATTGTTCCAGACACGTGACCATGTGCTCAGCCAGGCTGAAGAGGAATTATTAGCAGGAGCC
CAAGAAATTTTCAACGGCGCTGAAGAAACCTTTAGTATTCTTGATAACGCTGATATTGTCTTTCCAGTAGTTAAAAATGA
TAAGGGGGAAGATGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATCTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTAGCTGTTTTTGGTAAAGATTACGCAGATCGTGTGCATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCATGTCAATAAAGGGAAGCGTTCTGGAGCTTATTCGGGTGGTTCCTATGATACCAATGCCTTTATGCTATTAAACT
GGCAAGATACCTTAGACAATCTATACACTTTAGTTCATGAAACTGGGCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGAGATTACAGTATTTTCTTGGCAGAAATTGCATCCACAACGAATGAAAATATTATGACAGAAGC
TCTCTTAAATGAGGTTCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGACGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGACAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAATTGACGCGGCTAAGGATTTTTCAGGTCATTTACTAGATTCTAGCGCTAATC
TGTTGACAATTACAGATACTTATTTAGAGTTAGCTCGTCGTGTTGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTGTTTTC
ATTCTATGACCCAGAAGTTATGGCATTGAGTCAGGAAGATTACCAAGCTTTTCTTGCGGAAACACCTGATTTAAAAAGGT
ATCATCATTTCTTTGACAAATTGTTCCAGACACGTGACCATGTGCTCAGCCAGGCTGAAGAGGAATTATTAGCAGGAGCC
CAAGAAATTTTCAACGGCGCTGAAGAAACCTTTAGTATTCTTGATAACGCTGATATTGTCTTTCCAGTAGTTAAAAATGA
TAAGGGGGAAGATGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATCTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTAGCTGTTTTTGGTAAAGATTACGCAGATCGTGTGCATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCATGTCAATAAAGGGAAGCGTTCTGGAGCTTATTCGGGTGGTTCCTATGATACCAATGCCTTTATGCTATTAAACT
GGCAAGATACCTTAGACAATCTATACACTTTAGTTCATGAAACTGGGCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGAGATTACAGTATTTTCTTGGCAGAAATTGCATCCACAACGAATGAAAATATTATGACAGAAGC
TCTCTTAAATGAGGTTCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGACGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGACAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pepF | Streptococcus salivarius strain HSISS4 |
71.215 |
100 |
0.712 |