Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   DQM80_RS08925 Genome accession   NZ_LS483399
Coordinates   1737872..1738585 (+) Length   237 a.a.
NCBI ID   WP_002982243.1    Uniprot ID   A0A9X5LXW4
Organism   Streptococcus pyogenes strain NCTC8227     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1732872..1743585
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM80_RS08915 (NCTC8227_01768) treC 1733942..1735570 (-) 1629 WP_111702335.1 alpha,alpha-phosphotrehalase -
  DQM80_RS08920 (NCTC8227_01769) treP 1735637..1737661 (-) 2025 WP_011889218.1 PTS system trehalose-specific EIIBC component -
  DQM80_RS08925 (NCTC8227_01770) treR 1737872..1738585 (+) 714 WP_002982243.1 trehalose operon repressor Regulator
  DQM80_RS08935 (NCTC8227_01771) - 1738864..1739183 (-) 320 Protein_1679 winged helix-turn-helix transcriptional regulator -
  DQM80_RS08940 (NCTC8227_01772) - 1739369..1740226 (+) 858 WP_111702337.1 VOC family protein -
  DQM80_RS08945 (NCTC8227_01773) yaaA 1740268..1740999 (+) 732 WP_011889219.1 peroxide stress protein YaaA -
  DQM80_RS08950 (NCTC8227_01774) nrdG 1741173..1741787 (-) 615 WP_002982219.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  DQM80_RS08955 (NCTC8227_01775) - 1741787..1742296 (-) 510 WP_002991345.1 GNAT family N-acetyltransferase -
  DQM80_RS08960 (NCTC8227_01776) - 1742305..1743240 (-) 936 WP_002992828.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27592.78 Da        Isoelectric Point: 9.6226

>NTDB_id=1140252 DQM80_RS08925 WP_002982243.1 1737872..1738585(+) (treR) [Streptococcus pyogenes strain NCTC8227]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=1140252 DQM80_RS08925 WP_002982243.1 1737872..1738585(+) (treR) [Streptococcus pyogenes strain NCTC8227]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTTTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679

Multiple sequence alignment