Detailed information NTG1140246

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM80_RS07280
• Genome accession: NZ_LS483399
• Coordinates: 1394770..1395495 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC8227
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1389770..1400495

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM80_RS07245 (NCTC8227_01452)	rnpM	1389799..1390095 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQM80_RS07250 (NCTC8227_01453)	nusA	1390111..1391268 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQM80_RS07255 (NCTC8227_01454)	rimP	1391443..1391979 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQM80_RS07265 (NCTC8227_01456)	trmB	1392243..1392878 (-)	636	WP_011184863.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM80_RS07270 (NCTC8227_01457)	ccrZ	1392878..1393669 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM80_RS07275 (NCTC8227_01458)	-	1393733..1394767 (-)	1035	WP_111702249.1	ABC transporter permease	-
DQM80_RS07280 (NCTC8227_01459)	pptA	1394770..1395495 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM80_RS07285 (NCTC8227_01460)	-	1395567..1395986 (+)	420	WP_002983376.1	HIT family protein	-
DQM80_RS07290 (NCTC8227_01461)	-	1395983..1396339 (+)	357	WP_002988657.1	hypothetical protein	-
DQM80_RS07295 (NCTC8227_01462)	brpA	1396450..1397733 (-)	1284	WP_011184864.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM80_RS07300 (NCTC8227_01463)	-	1397742..1398266 (-)	525	WP_011184865.1	GNAT family N-acetyltransferase	-
DQM80_RS07305 (NCTC8227_01464)	tsaE	1398241..1398702 (-)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM80_RS07310 (NCTC8227_01465)	-	1398856..1400316 (-)	1461	WP_002988645.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140246 DQM80_RS07280 WP_002983379.1 1394770..1395495(-) (pptA) [Streptococcus pyogenes strain NCTC8227]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140246 DQM80_RS07280 WP_002983379.1 1394770..1395495(-) (pptA) [Streptococcus pyogenes strain NCTC8227]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCTTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714