Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   DQM80_RS05500 Genome accession   NZ_LS483399
Coordinates   1072442..1074247 (-) Length   601 a.a.
NCBI ID   WP_030127119.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8227     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1067442..1079247
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM80_RS05485 (NCTC8227_01101) prsA 1068980..1070035 (-) 1056 WP_111702179.1 peptidylprolyl isomerase PrsA -
  DQM80_RS05490 (NCTC8227_01102) - 1070098..1070805 (-) 708 WP_011017939.1 O-methyltransferase -
  DQM80_RS05495 (NCTC8227_01103) - 1070871..1072067 (-) 1197 WP_111702180.1 OFA family MFS transporter -
  DQM80_RS05500 (NCTC8227_01104) pepF 1072442..1074247 (-) 1806 WP_030127119.1 oligoendopeptidase F Regulator
  DQM80_RS05505 (NCTC8227_01105) - 1074260..1075222 (-) 963 WP_111702181.1 competence protein CoiA -
  DQM80_RS05510 (NCTC8227_01106) - 1075517..1076233 (-) 717 WP_011528761.1 pseudouridine synthase -
  DQM80_RS05515 (NCTC8227_01107) nagB 1076352..1077056 (-) 705 WP_111702182.1 glucosamine-6-phosphate deaminase -
  DQM80_RS05520 (NCTC8227_01108) queA 1077258..1078286 (+) 1029 WP_002983989.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69408.48 Da        Isoelectric Point: 4.8408

>NTDB_id=1140235 DQM80_RS05500 WP_030127119.1 1072442..1074247(-) (pepF) [Streptococcus pyogenes strain NCTC8227]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKGFAGHLLDSSANLLKVTKTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMMLHQEDYQAFLTETPELKVYNHFFDKLFQAREHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPIVRNDKGENIELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=1140235 DQM80_RS05500 WP_030127119.1 1072442..1074247(-) (pepF) [Streptococcus pyogenes strain NCTC8227]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGTACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTCAGTGACTTAGCTACTGAAGTTGAGGCATCTAAAGGTTTTGCTGGTCATTTGCTGGATTCTAGTGCTAATT
TGTTAAAGGTTACAAAAACATATTTAGAATTGGCTCGTCGTGTGGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTGATGATGCTTCATCAAGAAGACTATCAGGCTTTCCTTACTGAAACCCCTGAGTTGAAAGTGT
ACAACCATTTCTTTGACAAATTATTCCAAGCCCGCGAACATGTTCTTAGTCAAGCAGAAGAGGAATTATTAGCAGGAGCT
CAAGAAATTTTCAATGGTGCGGAAGAAACCTTTAGCATTCTTGATAACGCTGACATTGTTTTCCCGATAGTCAGAAATGA
TAAAGGTGAAAACATTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCACGTCAAGCTGCCATGGCTGCTAACTTTATTCCAGAAGCTGTTTA
CGACACTTTATTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAGGATTACGCAGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGAGATTACAGTATTTTCTTGGCAGAAATTGCATCCACAACGAATGAAAATATTATGACAGAAGC
TCTCTTAAATGAGGTTCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGATGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(112-181)

Peptidase family M3 (Peptidase_M3)

(202-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

70.549

100

0.705

Multiple sequence alignment