Detailed information NTG1140185

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DQM95_RS09480
• Genome accession: NZ_LS483397
• Coordinates: 1866332..1868773 (-)
• Length: 813 a.a.
• NCBI ID: WP_046393739.1
• Uniprot ID: -
• Organism: Streptococcus uberis strain NCTC3858
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1861332..1873773

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM95_RS09470 (NCTC3858_01925)	groL	1864229..1865857 (-)	1629	WP_111686014.1	chaperonin GroEL	-
DQM95_RS09475 (NCTC3858_01926)	groES	1865903..1866190 (-)	288	WP_015912033.1	co-chaperone GroES	-
DQM95_RS09480 (NCTC3858_01927)	clpC	1866332..1868773 (-)	2442	WP_046393739.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQM95_RS09485 (NCTC3858_01928)	-	1868773..1869234 (-)	462	WP_015912035.1	CtsR family transcriptional regulator	-
DQM95_RS09490 (NCTC3858_01929)	-	1869448..1869651 (-)	204	WP_037593131.1	cold-shock protein	-
DQM95_RS09495 (NCTC3858_01930)	-	1869882..1870208 (+)	327	WP_231909964.1	hypothetical protein	-
DQM95_RS09500 (NCTC3858_01931)	-	1870210..1872279 (+)	2070	WP_046389728.1	sodium:proton antiporter	-
DQM95_RS09510 (NCTC3858_01933)	ahpC	1872750..1873313 (+)	564	WP_015912043.1	alkyl hydroperoxide reductase subunit C	-

Sequence

Protein

• Length: 813 a.a.
• Molecular weight: 90408.98 Da
• Isoelectric Point: 6.5280

>NTDB_id=1140185 DQM95_RS09480 WP_046393739.1 1866332..1868773(-) (clpC) [Streptococcus uberis strain NCTC3858]
MTDYSLKMQAIFKQAQYQAARFDSPYLETWHLLLAMVVVNNSLAGLVFNEFENKVALEEYEAAAILAIGKAPNDDIKEFE
YKGQSKTLSHILSIADAIRNVTHANEVGSEHVLFAILLNPDIMATRLLELAGFKIKDDGKGDLKLADLRKAIEIQAAYSK
ETIKAIYELRKPKKAKTGGTFSDMMKPAGTAGELSDYTRDLTEMASQGLLEPVIGREKEITRMVQVLSRKTKNNPVLVGE
AGVGKTALAYGLAQRIVTGEIPYELRDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGHIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFSKVLIEEPSVEDAYKILSGLKKSYESYHNVTISD
QAIKTAVKVAHRYLTSKHLPDSAIDLLDEASATVQSFVKKEAPAFITPIDQAIIKGDFKTVSQLLKASKAKPQKPTPVTE
EDIMSTLSKLSGIPLEKISKADSQKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQV
LDDGQLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDINHDHSAMEKRILEELKKTYRPEFINRIDEKVVFHS
LSQEDMRQVVTIMVQPLIKNLEEKGITLKMQPSALKYLSEVGYDVEMGARPLRRTIQTEIEDKLSEFILSGQLKTGKTLK
IGMSQGKLKFDMV

Nucleotide

• Length: 2442 bp

>NTDB_id=1140185 DQM95_RS09480 WP_046393739.1 1866332..1868773(-) (clpC) [Streptococcus uberis strain NCTC3858]
ATGACAGATTATTCACTCAAAATGCAAGCTATTTTTAAACAAGCACAATACCAAGCGGCGCGTTTTGATAGCCCCTATTT
AGAAACTTGGCACCTCTTATTGGCAATGGTTGTTGTTAATAATTCACTAGCTGGCCTTGTTTTTAATGAATTTGAAAATA
AGGTTGCCTTGGAAGAATATGAAGCGGCAGCTATCTTAGCCATTGGCAAAGCTCCAAATGATGATATTAAGGAGTTTGAA
TATAAAGGTCAGTCAAAAACACTTTCTCATATTTTGTCCATTGCTGATGCTATTCGAAATGTTACACATGCCAATGAAGT
AGGATCAGAGCATGTTCTTTTTGCTATCTTATTAAATCCTGATATTATGGCAACTCGTTTGCTAGAATTAGCTGGATTTA
AAATCAAAGATGATGGCAAAGGCGATTTGAAATTGGCTGATTTAAGAAAAGCCATTGAAATTCAAGCTGCTTATAGTAAA
GAAACCATTAAAGCTATCTACGAACTCAGAAAACCCAAAAAAGCCAAAACAGGCGGTACTTTCTCAGATATGATGAAACC
AGCTGGCACTGCGGGAGAATTATCAGATTATACGAGAGATTTGACAGAAATGGCAAGTCAAGGCTTACTTGAGCCTGTTA
TTGGCAGAGAAAAAGAAATCACTCGAATGGTTCAAGTCTTAAGTCGTAAAACGAAAAATAATCCAGTTTTAGTCGGTGAG
GCTGGTGTTGGTAAGACAGCATTGGCCTATGGCTTAGCCCAACGGATTGTGACTGGTGAGATTCCATATGAACTTCGTGA
TATGCGTGTCTTAGAATTAGACATGATGAGTGTGGTGGCAGGTACGCGTTTTCGTGGTGATTTTGAAGAACGCATGAATC
AAATTATTGATGATATTGAAAGTGATGGTCATATCATTCTCTTTGTCGATGAATTACACACTATTATGGGATCTGGCAGT
GGTATTGATAGCACTTTAGATGCTGCAAATATCCTCAAACCAGCTCTCTCAAGAGGAACCCTACATATGGTTGGGGCAAC
TACTCAAGAAGAGTATCAAAAACATATTGAAAAAGATGCCGCTTTATCTCGTCGTTTCTCAAAAGTTTTGATTGAAGAAC
CAAGTGTAGAGGATGCCTACAAGATACTATCAGGGTTGAAAAAATCTTACGAAAGCTATCATAATGTCACCATCTCGGAT
CAAGCCATCAAAACAGCAGTCAAAGTTGCTCATCGCTATTTGACGAGCAAGCACTTACCTGATTCTGCGATTGATTTATT
AGATGAAGCTAGCGCAACGGTTCAAAGTTTCGTCAAAAAAGAGGCGCCTGCCTTCATCACACCCATTGACCAAGCCATCA
TAAAAGGTGATTTTAAAACAGTTAGCCAACTTTTGAAAGCTTCCAAGGCTAAGCCCCAGAAACCAACTCCTGTTACTGAA
GAAGATATCATGTCTACATTAAGTAAATTGTCAGGAATTCCACTGGAAAAAATTAGCAAGGCAGATAGTCAGAAATACCT
TAACCTGGAAAAAGAATTGCATAAGCGTGTTATCGGTCAAGAGGATGCAGTCTCAGCAATTTCAAGAGCTATCAGACGCA
ATCAGTCTGGTATTCGAACAGGTAAACGTCCGATTGGCTCCTTTATGTTCCTTGGACCGACAGGTGTTGGGAAAACAGAA
TTAGCAAAAGCTTTAGCAGAACTCTTATTCGATGATGAATCAGCTCTCATTCGTTTTGATATGTCAGAATACATGGAAAA
ATTCGCTGCTAGCCGTTTAAATGGAGCACCTCCAGGATATGTTGGCTATGACGAGGGCGGTGAGTTGACCGAAAAAGTAC
GTAACAAGCCCTATTCTGTTCTTCTCTTCGATGAAGTTGAAAAAGCCCATCCAGATATCTTTAATGTTTTGTTACAAGTC
TTGGATGATGGACAATTAACGGATTCTCGTGGGCGAAAAGTCGATTTTTCAAATACAATCATTATCATGACAAGTAATTT
AGGTGCTACAGCGCTTCGAGATGATAAAACGGTTGGATTTGGTGCTAAAGATATCAACCATGATCATTCGGCCATGGAAA
AACGCATCTTAGAAGAATTGAAAAAAACCTACCGACCAGAATTTATCAACCGAATTGATGAAAAAGTTGTCTTCCATAGC
TTAAGTCAAGAAGACATGCGACAAGTTGTCACGATTATGGTTCAACCCTTGATTAAGAACTTGGAAGAAAAAGGGATTAC
CCTCAAAATGCAACCATCTGCATTAAAATATTTGTCTGAAGTCGGTTATGATGTTGAGATGGGGGCAAGGCCACTAAGAC
GAACCATCCAAACAGAAATCGAAGACAAGTTGTCAGAATTCATTTTATCTGGTCAACTTAAAACTGGTAAGACTTTAAAA
ATTGGTATGAGCCAAGGTAAATTAAAATTTGATATGGTCTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (375-451)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (104-136)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (19-51)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (721-801)

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (543-714)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	74.939	100	0.75
clpC	Streptococcus thermophilus LMG 18311	71.795	100	0.723
clpC	Streptococcus thermophilus LMD-9	71.673	100	0.722
clpC	Streptococcus pneumoniae TIGR4	65.271	99.877	0.652
clpC	Streptococcus pneumoniae Rx1	65.148	99.877	0.651
clpC	Streptococcus pneumoniae D39	65.148	99.877	0.651
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.94	100	0.512
clpC	Bacillus subtilis subsp. subtilis str. 168	44.299	100	0.459