Detailed information NTG1140108

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM37_RS06905
• Genome accession: NZ_LS483394
• Coordinates: 1354476..1355201 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC10880
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1349476..1360201

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM37_RS06870 (NCTC10880_01372)	rnpM	1349510..1349806 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQM37_RS06875 (NCTC10880_01373)	nusA	1349822..1350979 (-)	1158	WP_002994325.1	transcription termination factor NusA	-
DQM37_RS06880 (NCTC10880_01374)	rimP	1351154..1351690 (-)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQM37_RS06890 (NCTC10880_01376)	trmB	1351949..1352584 (-)	636	WP_111694937.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM37_RS06895 (NCTC10880_01377)	ccrZ	1352584..1353375 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM37_RS06900 (NCTC10880_01378)	-	1353439..1354473 (-)	1035	WP_010922583.1	ABC transporter permease	-
DQM37_RS06905 (NCTC10880_01379)	pptA	1354476..1355201 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM37_RS06910 (NCTC10880_01380)	-	1355273..1355692 (+)	420	WP_002983376.1	HIT family protein	-
DQM37_RS06915 (NCTC10880_01381)	-	1355689..1356045 (+)	357	WP_002988657.1	hypothetical protein	-
DQM37_RS06920 (NCTC10880_01382)	brpA	1356155..1357429 (-)	1275	WP_111694938.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM37_RS06925 (NCTC10880_01383)	-	1357438..1357962 (-)	525	WP_009880752.1	GNAT family N-acetyltransferase	-
DQM37_RS06930 (NCTC10880_01384)	tsaE	1357937..1358398 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM37_RS06935 (NCTC10880_01385)	-	1358552..1360012 (-)	1461	WP_012560892.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140108 DQM37_RS06905 WP_002983379.1 1354476..1355201(-) (pptA) [Streptococcus pyogenes strain NCTC10880]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140108 DQM37_RS06905 WP_002983379.1 1354476..1355201(-) (pptA) [Streptococcus pyogenes strain NCTC10880]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714