Detailed information NTG1140103

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM37_RS06075
• Genome accession: NZ_LS483394
• Coordinates: 1190717..1191754 (-)
• Length: 345 a.a.
• NCBI ID: WP_111694896.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10880
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1185717..1196754

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM37_RS06050 (NCTC10880_01215)	-	1185720..1186247 (-)	528	WP_002983837.1	Dps family protein	-
DQM37_RS06055 (NCTC10880_01216)	-	1186475..1187101 (+)	627	WP_002989076.1	prepilin peptidase	-
DQM37_RS06060 (NCTC10880_01218)	rlmN	1187183..1188243 (-)	1061	Protein_1127	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM37_RS06065 (NCTC10880_01219)	-	1188247..1188867 (-)	621	WP_002992791.1	YutD family protein	-
DQM37_RS06070 (NCTC10880_01221)	-	1189326..1190303 (-)	978	WP_023611793.1	LacI family DNA-binding transcriptional regulator	-
DQM37_RS06075 (NCTC10880_01222)	sepM	1190717..1191754 (-)	1038	WP_111694896.1	SepM family pheromone-processing serine protease	Regulator
DQM37_RS06080 (NCTC10880_01223)	coaD	1191741..1192232 (-)	492	WP_111694897.1	pantetheine-phosphate adenylyltransferase	-
DQM37_RS06085 (NCTC10880_01224)	rsmD	1192222..1192761 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM37_RS06090 (NCTC10880_01225)	asnA	1192884..1193876 (-)	993	WP_023611792.1	aspartate--ammonia ligase	-
DQM37_RS06095 (NCTC10880_01226)	arcC	1194189..1195139 (-)	951	WP_015057899.1	carbamate kinase	-
DQM37_RS06100 (NCTC10880_01227)	-	1195159..1196490 (-)	1332	WP_032460502.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37540.30 Da
• Isoelectric Point: 9.8226

>NTDB_id=1140103 DQM37_RS06075 WP_111694896.1 1190717..1191754(-) (sepM) [Streptococcus pyogenes strain NCTC10880]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDKVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1140103 DQM37_RS06075 WP_111694896.1 1190717..1191754(-) (sepM) [Streptococcus pyogenes strain NCTC10880]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATAAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACTAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.565	100	0.696