Detailed information NTG1140000

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQN61_RS07490
• Genome accession: NZ_LS483391
• Coordinates: 1412512..1413237 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC8320
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1407512..1418237

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN61_RS07455 (NCTC8320_01492)	rnpM	1407546..1407842 (-)	297	WP_002983486.1	RNase P modulator RnpM	-
DQN61_RS07460 (NCTC8320_01493)	nusA	1407858..1409015 (-)	1158	WP_002983485.1	transcription termination factor NusA	-
DQN61_RS07465 (NCTC8320_01494)	rimP	1409190..1409726 (-)	537	WP_002983483.1	ribosome maturation factor RimP	-
DQN61_RS07475 (NCTC8320_01496)	trmB	1409985..1410620 (-)	636	WP_011018101.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQN61_RS07480 (NCTC8320_01497)	ccrZ	1410620..1411411 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQN61_RS07485 (NCTC8320_01498)	-	1411475..1412509 (-)	1035	WP_002983381.1	ABC transporter permease	-
DQN61_RS07490 (NCTC8320_01499)	pptA	1412512..1413237 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQN61_RS07495 (NCTC8320_01500)	-	1413309..1413728 (+)	420	WP_002983376.1	HIT family protein	-
DQN61_RS07500 (NCTC8320_01501)	-	1413725..1414081 (+)	357	WP_011018102.1	hypothetical protein	-
DQN61_RS07505 (NCTC8320_01502)	brpA	1414192..1415475 (-)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQN61_RS07510 (NCTC8320_01503)	-	1415484..1416008 (-)	525	WP_002983369.1	GNAT family N-acetyltransferase	-
DQN61_RS07515 (NCTC8320_01504)	tsaE	1415983..1416444 (-)	462	WP_002983367.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQN61_RS07520 (NCTC8320_01505)	-	1416598..1418058 (-)	1461	WP_011018103.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1140000 DQN61_RS07490 WP_002983379.1 1412512..1413237(-) (pptA) [Streptococcus pyogenes strain NCTC8320]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1140000 DQN61_RS07490 WP_002983379.1 1412512..1413237(-) (pptA) [Streptococcus pyogenes strain NCTC8320]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714