Detailed information NTG1139789

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM45_RS02535
• Genome accession: NZ_LS483388
• Coordinates: 497066..498109 (+)
• Length: 347 a.a.
• NCBI ID: WP_003082628.1
• Uniprot ID: A0A4V0GZT7
• Organism: Streptococcus porcinus strain NCTC10999
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 492066..503109

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM45_RS02510 (NCTC10999_00512)	-	492488..493819 (+)	1332	WP_003084021.1	dipeptidase	-
DQM45_RS02515 (NCTC10999_00513)	arcC	493836..494786 (+)	951	WP_003082752.1	carbamate kinase	-
DQM45_RS02520 (NCTC10999_00514)	asnA	494965..495957 (+)	993	WP_003084554.1	aspartate--ammonia ligase	-
DQM45_RS02525 (NCTC10999_00515)	rsmD	496059..496598 (+)	540	WP_003084138.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM45_RS02530 (NCTC10999_00516)	coaD	496588..497079 (+)	492	WP_003084074.1	pantetheine-phosphate adenylyltransferase	-
DQM45_RS02535 (NCTC10999_00517)	sepM	497066..498109 (+)	1044	WP_003082628.1	SepM family pheromone-processing serine protease	Regulator
DQM45_RS02540 (NCTC10999_00518)	-	498239..500194 (+)	1956	WP_003084642.1	PTS sugar transporter subunit IIA	-
DQM45_RS02545 (NCTC10999_00519)	-	500222..500695 (+)	474	WP_039985002.1	PTS sugar transporter subunit IIA	-
DQM45_RS02550 (NCTC10999_00520)	-	500697..500975 (+)	279	WP_003083266.1	PTS sugar transporter subunit IIB	-
DQM45_RS02555 (NCTC10999_00521)	-	500987..502327 (+)	1341	WP_003085397.1	PTS galactitol transporter subunit IIC	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38318.33 Da
• Isoelectric Point: 10.1692

>NTDB_id=1139789 DQM45_RS02535 WP_003082628.1 497066..498109(+) (sepM) [Streptococcus porcinus strain NCTC10999]
MKIIKKVKWWLISILAVVALLFALFFPLPYYIEMPGGAYDIRSVLQINNKKDKEKGSYNFVAVSLSRATFAQILYAWVTP
FTEISSVENTTGGYSAADYMRINQYYMETSQNGAIYQALKLAGKPVSLDYLGVYVLDVNKDSTFRGVLNIADTVTGVNKK
EFKSSADLIKYVSSLKRGEQVTVQYTTGNEKRSKSGKVIKLKNGKNGIGIGLTDHTKVHTDEKIEFSTEGVGGPSAGLMF
TLDIYDQLNQENLRKGRRIAGTGTIDQDGKVGDIGGAGLKVVAAAKEGAEIFFVPNNPVDKRIKKVKPNAKTNYKEALDV
AKKLKTKMKIVPVRNVKEAIAYLQKTE

Nucleotide

• Length: 1044 bp

>NTDB_id=1139789 DQM45_RS02535 WP_003082628.1 497066..498109(+) (sepM) [Streptococcus porcinus strain NCTC10999]
ATGAAGATAATTAAAAAAGTCAAATGGTGGTTAATTAGTATTCTGGCAGTAGTTGCCCTCTTATTTGCCCTCTTTTTCCC
TTTACCTTATTATATTGAAATGCCTGGCGGTGCTTACGATATTCGTTCAGTACTCCAGATAAACAATAAGAAGGATAAGG
AAAAAGGCTCTTACAATTTTGTAGCGGTTAGTTTGAGTCGAGCTACCTTTGCGCAAATCCTTTATGCTTGGGTAACGCCA
TTTACAGAGATTTCATCTGTAGAAAATACAACTGGTGGTTACAGTGCAGCAGATTATATGCGTATTAATCAATATTACAT
GGAGACCTCTCAAAATGGAGCTATCTACCAAGCTTTAAAATTAGCTGGAAAACCTGTTTCATTAGACTATTTAGGTGTTT
ATGTTTTGGATGTTAATAAAGATTCAACTTTTCGTGGTGTTTTAAATATTGCAGATACAGTTACAGGAGTCAATAAAAAG
GAATTTAAAAGTTCAGCTGATCTCATTAAATACGTTTCAAGTTTGAAACGAGGTGAACAGGTAACGGTTCAATACACTAC
TGGTAATGAGAAAAGATCCAAAAGTGGTAAGGTCATTAAGCTAAAAAACGGTAAAAATGGTATTGGTATTGGTTTAACAG
ACCACACAAAAGTACATACAGACGAAAAAATTGAGTTTTCAACAGAAGGTGTAGGTGGGCCAAGTGCTGGACTTATGTTT
ACACTGGATATTTATGATCAACTGAATCAAGAAAATCTGCGTAAAGGTCGTCGTATTGCAGGTACTGGAACAATTGATCA
AGATGGTAAAGTTGGTGATATTGGTGGTGCAGGTTTAAAAGTCGTGGCTGCAGCCAAGGAAGGTGCAGAGATTTTCTTCG
TGCCTAATAACCCAGTTGATAAGCGTATCAAAAAAGTGAAGCCAAATGCAAAGACCAATTACAAAGAGGCCTTAGATGTA
GCAAAAAAATTAAAAACCAAGATGAAAATCGTCCCAGTTAGAAATGTTAAAGAAGCTATTGCTTATTTGCAAAAGACTGA
ATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (131-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-340)

3D structure

• AlphaFold DB: A0A4V0GZT7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.304	99.424	0.709