Detailed information NTG1139629

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: DQM63_RS03860
• Genome accession: NZ_LS483385
• Coordinates: 746339..747199 (+)
• Length: 286 a.a.
• NCBI ID: WP_002900735.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain NCTC7863
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 741339..752199

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM63_RS03830 (NCTC7863_00746)	-	741595..742476 (+)	882	WP_002895995.1	F0F1 ATP synthase subunit gamma	-
DQM63_RS03835 (NCTC7863_00747)	atpD	742515..743921 (+)	1407	WP_002897903.1	F0F1 ATP synthase subunit beta	-
DQM63_RS03840 (NCTC7863_00748)	-	743929..744351 (+)	423	WP_002900740.1	F0F1 ATP synthase subunit epsilon	-
DQM63_RS03845 (NCTC7863_00749)	-	744525..744755 (+)	231	WP_002895990.1	DUF1146 family protein	-
DQM63_RS03850 (NCTC7863_00750)	murA	744823..746103 (+)	1281	WP_002900738.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQM63_RS03855 (NCTC7863_00751)	-	746096..746278 (+)	183	WP_002900736.1	DNA-directed RNA polymerase subunit beta	-
DQM63_RS03860 (NCTC7863_00752)	endA	746339..747199 (+)	861	WP_002900735.1	DNA/RNA non-specific endonuclease	Machinery gene
DQM63_RS03865 (NCTC7863_00753)	-	747377..748096 (+)	720	WP_002902711.1	matrixin family metalloprotease	-
DQM63_RS03870 (NCTC7863_00754)	-	748101..748466 (+)	366	WP_002900732.1	hypothetical protein	-
DQM63_RS03875 (NCTC7863_00755)	-	748566..750461 (+)	1896	WP_032909515.1	ABC-F family ATP-binding cassette domain-containing protein	-
DQM63_RS03880 (NCTC7863_00756)	-	750621..751178 (+)	558	WP_002900729.1	hypothetical protein	-
DQM63_RS03885 (NCTC7863_00757)	-	751267..752010 (+)	744	WP_002913733.1	hypothetical protein	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31314.98 Da
• Isoelectric Point: 10.0558

>NTDB_id=1139629 DQM63_RS03860 WP_002900735.1 746339..747199(+) (endA) [Streptococcus sanguinis strain NCTC7863]
MKRKTSQKRNSKSLQGWAGLTLALILALAGYFWGQDGQQPLQSPNSEIRVGQVQDQGTPSRELAESVLTDAVRAQLKGSI
EWNGAGAFIVNGNKTDLDAGISSKPYADNKTKLVQGQTLPTVANAFLSKSTRQYKKREETRNANTSWVPAGWHQLKNLPG
EYNHAVDRGHLLAYSLIGGLKGFDASTSNPANIAVQTAWSNQANEADSTGQNYYETKIRKALDKNKRVRYRVTLIYATET
DLVPVGSHLEAKSSDGSLEFNVFIPNVQKGIRLDYNSGKVSQETGS

Nucleotide

• Length: 861 bp

>NTDB_id=1139629 DQM63_RS03860 WP_002900735.1 746339..747199(+) (endA) [Streptococcus sanguinis strain NCTC7863]
ATGAAAAGAAAGACTAGTCAGAAAAGGAATTCTAAGAGCCTGCAAGGCTGGGCTGGGCTGACTCTAGCCTTGATTTTGGC
GCTGGCTGGCTATTTCTGGGGACAGGATGGTCAGCAGCCACTTCAGAGTCCAAATTCAGAAATCAGAGTTGGGCAAGTTC
AAGATCAGGGCACCCCTAGTCGGGAACTGGCTGAGAGCGTTCTGACGGATGCTGTCCGAGCTCAGCTTAAAGGCAGCATT
GAATGGAATGGAGCTGGTGCCTTTATCGTGAATGGGAATAAGACAGACTTGGATGCGGGGATTTCTAGTAAGCCCTACGC
TGACAATAAGACCAAGCTTGTACAAGGGCAAACCCTTCCGACAGTGGCGAATGCCTTTTTATCCAAGTCTACCCGCCAGT
ACAAAAAACGGGAAGAAACTAGAAATGCCAACACTTCATGGGTACCGGCAGGCTGGCATCAACTCAAGAACCTCCCTGGT
GAGTACAATCACGCTGTGGACCGCGGACATCTCTTGGCCTATTCGCTGATCGGTGGTTTGAAGGGCTTTGATGCTTCTAC
TAGCAATCCTGCCAATATCGCTGTGCAGACGGCCTGGTCCAACCAAGCCAATGAAGCGGATTCGACAGGGCAGAATTACT
ATGAGACAAAGATCCGTAAGGCCCTGGATAAGAACAAGCGGGTGCGCTACCGGGTAACCTTGATTTATGCCACGGAGACT
GATTTAGTACCGGTTGGGTCACATTTAGAGGCCAAGTCCAGCGATGGCAGTCTAGAATTCAATGTCTTTATTCCGAATGT
GCAAAAAGGGATTCGTTTGGACTATAATAGTGGCAAGGTCAGTCAGGAGACGGGTTCTTAA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (88-256)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	74.439	77.972	0.58
endA	Streptococcus pneumoniae D39	74.439	77.972	0.58
endA	Streptococcus pneumoniae R6	74.439	77.972	0.58
endA	Streptococcus pneumoniae TIGR4	74.439	77.972	0.58