Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQM63_RS00870 Genome accession   NZ_LS483385
Coordinates   155743..158172 (+) Length   809 a.a.
NCBI ID   WP_002902081.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 150743..163172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS00835 (NCTC7863_00162) nusG 150751..151287 (+) 537 WP_002894018.1 transcription termination/antitermination protein NusG -
  DQM63_RS00840 (NCTC7863_00163) - 151373..152137 (-) 765 WP_002902076.1 hypothetical protein -
  DQM63_RS00850 (NCTC7863_00165) rpsB 152645..153427 (+) 783 WP_002902077.1 30S ribosomal protein S2 -
  DQM63_RS00855 (NCTC7863_00166) tsf 153500..154543 (+) 1044 WP_002894014.1 translation elongation factor Ts -
  DQM63_RS00860 (NCTC7863_00167) - 154643..155131 (-) 489 WP_002902079.1 hypothetical protein -
  DQM63_RS00865 (NCTC7863_00168) - 155278..155742 (+) 465 WP_002899234.1 CtsR family transcriptional regulator -
  DQM63_RS00870 (NCTC7863_00169) clpC 155743..158172 (+) 2430 WP_002902081.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM63_RS00875 (NCTC7863_00170) - 158266..159009 (+) 744 WP_002902083.1 DUF4272 domain-containing protein -
  DQM63_RS00880 (NCTC7863_00171) - 159051..159536 (+) 486 WP_002902084.1 hypothetical protein -
  DQM63_RS00885 (NCTC7863_00172) - 159520..159921 (+) 402 WP_002902085.1 DUF4430 domain-containing protein -
  DQM63_RS00890 (NCTC7863_00173) - 160107..161165 (+) 1059 WP_002902086.1 AAA family ATPase -
  DQM63_RS00895 (NCTC7863_00174) pnuC 161187..162002 (+) 816 WP_002902087.1 nicotinamide riboside transporter PnuC -
  DQM63_RS00900 (NCTC7863_00175) - 162057..162845 (+) 789 WP_002902088.1 NUDIX hydrolase -

Sequence

Protein


Download         Length: 809 a.a.        Molecular weight: 89570.08 Da        Isoelectric Point: 5.1953

>NTDB_id=1139605 DQM63_RS00870 WP_002902081.1 155743..158172(+) (clpC) [Streptococcus sanguinis strain NCTC7863]
MKYSKALIESLEAAQLLAGHFTTDYLESWHLLIALANNPYSVAGSVLNEFPVEVDGFEEAAFQITGQAYQKDGHFELLPF
SYRLEELFEEAGQIAEAVRAKHVGTEHVLLAMLFDRGTLASRILEFTGFSYEDKEQGPKISDLRKVLEQRAGWGKEDIKA
IRSLNKGVMAAKQTMANMMGMPASTSGGLEDYTRDLTELARDGRLEPVIGRDQEISRIVQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPAELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVSIEEPNVADSIAILQGLRKSYEDHHKVQISDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVQNRGPQNYEQSDLTPVDQALMAADFKKVSKLLEQEQQPKLYKLKVEEDDVL
ATLSGLSGIPVQKLTQTDAKKYLNLETELHKRVIGQDEAISAISRAIRRNQSGIRSSKRPIGSFMFLGPTGVGKTELAKA
LAESLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
QLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDIRLDHANMEKRMLEELNKAYRPEFINRIDEKVVFHSLSAE
DMQEVVKVMVKPLIASLAEKGIELKFQASALKLLAQEGYDVEMGARPLRRTLQTQVEDKLSELLLTGDLTAGQTLKVGVK
AGQLKFEVA

Nucleotide


Download         Length: 2430 bp        

>NTDB_id=1139605 DQM63_RS00870 WP_002902081.1 155743..158172(+) (clpC) [Streptococcus sanguinis strain NCTC7863]
ATGAAATACTCAAAAGCCTTAATAGAAAGCTTGGAAGCAGCCCAGCTCTTGGCCGGCCATTTTACGACAGATTATCTGGA
ATCATGGCATCTGCTGATTGCTCTGGCTAATAATCCCTACAGCGTTGCTGGTTCAGTCCTCAATGAGTTTCCTGTGGAAG
TTGATGGATTTGAAGAAGCAGCTTTTCAGATTACTGGTCAGGCTTATCAGAAAGACGGTCACTTCGAGCTGCTGCCTTTT
TCTTATCGCTTAGAGGAGTTGTTTGAGGAGGCGGGCCAGATTGCAGAAGCTGTTCGGGCTAAGCATGTAGGTACTGAACA
TGTGCTGCTGGCTATGTTATTTGACCGGGGGACCTTGGCCTCTCGTATTCTGGAATTTACTGGCTTTAGCTACGAGGACA
AGGAGCAGGGACCGAAAATCAGTGATTTGCGAAAGGTCTTGGAGCAGCGAGCTGGCTGGGGCAAGGAAGATATCAAGGCT
ATTCGCAGTCTGAATAAGGGAGTAATGGCCGCTAAGCAGACCATGGCCAATATGATGGGTATGCCAGCTTCTACTAGCGG
TGGTCTGGAAGACTACACCCGTGATCTGACGGAGCTGGCTAGAGATGGCCGATTGGAGCCCGTCATTGGCCGCGATCAAG
AAATTTCACGGATAGTTCAGATTCTCAGTCGTAAGACTAAAAACAATCCAGTGCTGGTTGGAGATGCTGGGGTTGGTAAG
ACAGCTCTGGCTTTAGGACTGGCTCAGCGTGTAGCGGCTGGTCAGGTTCCGGCTGAACTTGCTAAGATGCGGGTTTTGGA
GCTGGACTTGATGAATGTAGTCGCTGGCACTCGCTTTCGCGGAGACTTCGAGGAGCGGATGAACAACATCATCAATGACA
TTGAAGAAGATGGTCATGTCATTCTCTTCATCGATGAGCTGCATACTATCATGGGATCTGGCAGCGGTATTGACTCGACT
TTGGATGCAGCCAATATCCTGAAACCGGCTCTGGCTCGTGGAACCTTGCGAACTGTTGGTGCCACGACGCAGGAAGAGTA
TCAGAAACATATTGAAAAAGATGCGGCCCTTTCCCGGCGTTTTGCTAAGGTCAGCATAGAAGAGCCTAATGTGGCTGACA
GCATTGCTATTTTACAAGGCTTGAGAAAGAGCTATGAGGACCATCACAAGGTACAGATTAGTGATCAAGCGATTGAGACG
GCGGTGAAATATGCCCATCGCTATCTGACTAGCAAGCATCTGCCGGACTCTGCCATTGATCTTTTGGACGAGGCCAGTGC
AACAGTGCAGAATAGAGGACCACAGAATTACGAGCAGTCGGATTTGACGCCAGTGGATCAAGCCTTGATGGCAGCGGACT
TTAAAAAGGTGTCGAAGTTGCTTGAGCAAGAGCAGCAACCGAAGCTTTATAAACTAAAAGTGGAAGAAGACGATGTCTTG
GCTACTCTGAGTGGCTTGTCTGGTATTCCAGTGCAGAAGCTGACTCAGACAGATGCAAAGAAATACCTCAACTTGGAAAC
AGAACTGCATAAACGCGTGATTGGGCAGGACGAGGCGATTTCAGCTATCAGCCGAGCTATCCGACGGAACCAGTCTGGTA
TCCGCAGCAGCAAGCGGCCGATTGGCTCCTTTATGTTCCTAGGTCCGACAGGAGTCGGGAAGACAGAGCTAGCCAAGGCC
TTGGCCGAAAGTCTCTTTGATGACGAGTCTGCTCTCATCCGCTTTGATATGAGTGAGTACATGGAGAAATTCGCGGCTAG
CCGTCTCAACGGAGCGCCCCCAGGCTATGTAGGCTATGAAGAAGGAGGGGAGCTGACGGAAAAGGTGCGCAACAGACCTT
ATTCTGTCCTGCTCTTTGACGAGGTGGAAAAGGCGCACCCAGATATTTTCAATGTTCTCCTGCAGGTCTTGGATGATGGC
CAGTTGACTGACAGCAAGGGCCGCAAGGTGGACTTCTCCAACACGATTATTATCATGACCAGCAATCTGGGGGCGACCAG
TTTGCGGGATGATAAGACGGTGGGCTTTGGTGCGCGGGACATTCGCTTGGACCATGCCAATATGGAAAAACGGATGCTGG
AAGAACTCAATAAAGCATATAGACCAGAGTTTATCAACCGTATTGACGAGAAGGTAGTCTTCCACAGCTTATCTGCTGAA
GATATGCAGGAAGTGGTCAAGGTTATGGTCAAACCGCTCATTGCAAGTCTCGCTGAGAAGGGAATTGAGCTGAAATTTCA
GGCTAGTGCCCTTAAGCTGCTGGCTCAGGAAGGATACGATGTGGAAATGGGAGCACGGCCATTGCGTCGCACTCTACAGA
CTCAGGTAGAGGACAAGCTGTCTGAGCTCCTCTTGACAGGAGATTTGACTGCTGGTCAGACTCTTAAGGTCGGGGTCAAG
GCTGGCCAACTCAAGTTCGAAGTGGCCTAG

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(14-60)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(100-133)

AAA lid domain (AAA_lid_9)

(371-459)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(717-797)

AAA domain (Cdc48 subfamily) (AAA_2)

(539-710)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae TIGR4

77.654

100

0.777
  clpC Streptococcus pneumoniae Rx1

77.654

100

0.777
  clpC Streptococcus pneumoniae D39

77.654

100

0.777
  clpC Streptococcus mutans UA159

67.813

100

0.682
  clpC Streptococcus thermophilus LMG 18311

66.79

100

0.671
  clpC Streptococcus thermophilus LMD-9

66.667

100

0.67
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.605

100

0.517
  clpC Bacillus subtilis subsp. subtilis str. 168

45.443

99.011

0.45
  clpE Streptococcus pneumoniae TIGR4

46.094

79.11

0.365
  clpE Streptococcus pneumoniae Rx1

46.094

79.11

0.365
  clpE Streptococcus pneumoniae D39

46.094

79.11

0.365
  clpE Streptococcus pneumoniae R6

46.094

79.11

0.365
  clpE Streptococcus mutans UA159

47.65

76.267

0.363

Multiple sequence alignment