Detailed information NTG1139566

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM87_RS02350
• Genome accession: NZ_LS483384
• Coordinates: 435371..436096 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13743
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 430371..441096

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM87_RS02320 (NCTC13743_00458)	-	430559..432019 (+)	1461	WP_111704936.1	NCS2 family permease	-
DQM87_RS02325 (NCTC13743_00459)	tsaE	432173..432634 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM87_RS02330 (NCTC13743_00460)	-	432609..433133 (+)	525	WP_111704937.1	GNAT family N-acetyltransferase	-
DQM87_RS02335 (NCTC13743_00461)	brpA	433142..434416 (+)	1275	WP_020837594.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM87_RS02340 (NCTC13743_00462)	-	434527..434883 (-)	357	WP_009880754.1	hypothetical protein	-
DQM87_RS02345 (NCTC13743_00463)	-	434880..435299 (-)	420	WP_002983376.1	HIT family protein	-
DQM87_RS02350 (NCTC13743_00464)	pptA	435371..436096 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM87_RS02355 (NCTC13743_00465)	-	436099..437133 (+)	1035	WP_010922583.1	ABC transporter permease	-
DQM87_RS02360 (NCTC13743_00466)	ccrZ	437197..437988 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM87_RS02365 (NCTC13743_00467)	trmB	437988..438623 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM87_RS02375 (NCTC13743_00469)	rimP	438882..439418 (+)	537	WP_002988815.1	ribosome maturation factor RimP	-
DQM87_RS02380 (NCTC13743_00470)	nusA	439593..440750 (+)	1158	WP_002988817.1	transcription termination factor NusA	-
DQM87_RS02385 (NCTC13743_00471)	rnpM	440766..441062 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1139566 DQM87_RS02350 WP_002983379.1 435371..436096(+) (pptA) [Streptococcus pyogenes strain NCTC13743]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1139566 DQM87_RS02350 WP_002983379.1 435371..436096(+) (pptA) [Streptococcus pyogenes strain NCTC13743]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714