Detailed information NTG1139561

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: DQM87_RS01555
• Genome accession: NZ_LS483384
• Coordinates: 276862..277932 (+)
• Length: 356 a.a.
• NCBI ID: WP_009880666.1
• Uniprot ID: Q54910
• Organism: Streptococcus pyogenes strain NCTC13743
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 271862..282932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM87_RS01540 (NCTC13743_00307)	amiA	272390..274360 (+)	1971	WP_111704906.1	peptide ABC transporter substrate-binding protein	Regulator
DQM87_RS01545 (NCTC13743_00308)	amiC	274425..275927 (+)	1503	WP_011017334.1	ABC transporter permease	Regulator
DQM87_RS01550 (NCTC13743_00309)	amiD	275927..276853 (+)	927	WP_111704907.1	oligopeptide ABC transporter permease OppC	Regulator
DQM87_RS01555 (NCTC13743_00310)	amiE	276862..277932 (+)	1071	WP_009880666.1	ABC transporter ATP-binding protein	Regulator
DQM87_RS01560 (NCTC13743_00311)	amiF	277925..278848 (+)	924	WP_002986000.1	ABC transporter ATP-binding protein	Regulator
DQM87_RS09835	-	278886..278969 (-)	84	Protein_255	IS3 family transposase	-
DQM87_RS09840	-	279103..279413 (-)	311	Protein_256	IS3 family transposase	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 39645.74 Da
• Isoelectric Point: 5.8952

>NTDB_id=1139561 DQM87_RS01555 WP_009880666.1 276862..277932(+) (amiE) [Streptococcus pyogenes strain NCTC13743]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQGLHQKILRKMSQQEEGNV

Nucleotide

• Length: 1071 bp

>NTDB_id=1139561 DQM87_RS01555 WP_009880666.1 276862..277932(+) (amiE) [Streptococcus pyogenes strain NCTC13743]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGGTTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-299)

3D structure

• AlphaFold DB: Q54910

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	76.667	100	0.775
amiE	Streptococcus thermophilus LMG 18311	75.556	100	0.764
amiE	Streptococcus thermophilus LMD-9	75.556	100	0.764
oppD	Streptococcus mutans UA159	56.677	94.663	0.537