Detailed information
Bioinformatically predicted
Overview
| Name | sepM | Type | Regulator |
| Locus tag | DQM67_RS02775 | Genome accession | NZ_LS483383 |
| Coordinates | 534628..535695 (+) | Length | 355 a.a. |
| NCBI ID | WP_037586341.1 | Uniprot ID | - |
| Organism | Streptococcus cristatus ATCC 51100 strain NCTC 12479 | ||
| Function | processing of CSP (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 505512..552893 | 534628..535695 | within | 0 |
Gene organization within MGE regions
Location: 505512..552893
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| DQM67_RS02605 (NCTC12479_00496) | - | 506195..507736 (+) | 1542 | WP_005592326.1 | ABC-F family ATP-binding cassette domain-containing protein | - |
| DQM67_RS02610 (NCTC12479_00497) | - | 507857..508282 (-) | 426 | WP_005592332.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| DQM67_RS02615 (NCTC12479_00498) | - | 508345..508779 (+) | 435 | WP_005590862.1 | GNAT family N-acetyltransferase | - |
| DQM67_RS02620 (NCTC12479_00499) | - | 508836..509153 (-) | 318 | WP_005590860.1 | DUF960 domain-containing protein | - |
| DQM67_RS02625 (NCTC12479_00500) | - | 509340..509873 (-) | 534 | WP_005590859.1 | DUF402 domain-containing protein | - |
| DQM67_RS02630 (NCTC12479_00501) | recX | 509960..510736 (-) | 777 | WP_005590857.1 | recombination regulator RecX | - |
| DQM67_RS02635 (NCTC12479_00502) | - | 510763..511539 (-) | 777 | WP_005592368.1 | aminoglycoside 3'-phosphotransferase | - |
| DQM67_RS02640 (NCTC12479_00503) | rlmD | 511595..512953 (+) | 1359 | WP_005590853.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| DQM67_RS02650 (NCTC12479_00504) | - | 513186..514118 (-) | 933 | WP_005590852.1 | nitronate monooxygenase | - |
| DQM67_RS02655 (NCTC12479_00505) | - | 514412..514642 (+) | 231 | WP_005590851.1 | DUF1858 domain-containing protein | - |
| DQM67_RS02660 (NCTC12479_00506) | - | 514645..516006 (+) | 1362 | WP_005590850.1 | DUF438 domain-containing protein | - |
| DQM67_RS02665 (NCTC12479_00507) | - | 516033..516287 (+) | 255 | WP_002899692.1 | DUF1912 family protein | - |
| DQM67_RS02675 (NCTC12479_00509) | - | 516633..517196 (+) | 564 | WP_005590849.1 | GNAT family N-acetyltransferase | - |
| DQM67_RS02680 (NCTC12479_00510) | - | 517193..518020 (+) | 828 | WP_005592404.1 | hypothetical protein | - |
| DQM67_RS02685 (NCTC12479_00511) | - | 518100..520751 (+) | 2652 | WP_005590847.1 | valine--tRNA ligase | - |
| DQM67_RS02690 (NCTC12479_00512) | - | 520827..522287 (+) | 1461 | WP_045501579.1 | class I SAM-dependent DNA methyltransferase | - |
| DQM67_RS10430 (NCTC12479_00513) | - | 522291..522722 (+) | 432 | WP_005592353.1 | ATP-binding protein | - |
| DQM67_RS02695 (NCTC12479_00514) | - | 522656..524497 (+) | 1842 | WP_231913455.1 | ATP-binding protein | - |
| DQM67_RS02700 (NCTC12479_00515) | - | 524520..525143 (+) | 624 | WP_005590843.1 | hypothetical protein | - |
| DQM67_RS02705 (NCTC12479_00516) | - | 525136..525768 (+) | 633 | WP_005590842.1 | HNH endonuclease | - |
| DQM67_RS02710 (NCTC12479_00517) | - | 526025..527275 (+) | 1251 | WP_005590841.1 | diaminopimelate decarboxylase | - |
| DQM67_RS02715 (NCTC12479_00518) | - | 527333..527581 (+) | 249 | WP_005590840.1 | YneF family protein | - |
| DQM67_RS02720 (NCTC12479_00519) | racE | 527681..528475 (+) | 795 | WP_005590839.1 | glutamate racemase | - |
| DQM67_RS02725 (NCTC12479_00520) | - | 528472..529449 (+) | 978 | WP_005590837.1 | nucleoside-triphosphate diphosphatase | - |
| DQM67_RS02730 (NCTC12479_00521) | - | 529425..529946 (+) | 522 | WP_005590835.1 | metallophosphoesterase | - |
| DQM67_RS02735 (NCTC12479_00522) | cbpB | 529943..530404 (+) | 462 | WP_005590833.1 | cyclic-di-AMP-binding protein CbpB | - |
| DQM67_RS02740 (NCTC12479_00523) | xerD | 530401..531132 (+) | 732 | WP_005590831.1 | site-specific tyrosine recombinase XerD | - |
| DQM67_RS02745 (NCTC12479_00524) | - | 531135..531845 (+) | 711 | WP_005590830.1 | segregation/condensation protein A | - |
| DQM67_RS02750 (NCTC12479_00525) | scpB | 531838..532383 (+) | 546 | WP_005590827.1 | SMC-Scp complex subunit ScpB | - |
| DQM67_RS02755 (NCTC12479_00526) | - | 532517..533248 (+) | 732 | WP_005592340.1 | pseudouridine synthase | - |
| DQM67_RS02760 | yidD | 533245..533505 (+) | 261 | WP_005592331.1 | membrane protein insertion efficiency factor YidD | - |
| DQM67_RS02765 (NCTC12479_00527) | rsmD | 533591..534130 (+) | 540 | WP_037586339.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD | - |
| DQM67_RS02770 (NCTC12479_00528) | coaD | 534120..534605 (+) | 486 | WP_005590821.1 | pantetheine-phosphate adenylyltransferase | - |
| DQM67_RS02775 (NCTC12479_00529) | sepM | 534628..535695 (+) | 1068 | WP_037586341.1 | SepM family pheromone-processing serine protease | Regulator |
| DQM67_RS02780 (NCTC12479_00530) | - | 535858..536421 (+) | 564 | WP_005590819.1 | YutD family protein | - |
| DQM67_RS02785 (NCTC12479_00531) | rlmN | 536431..537519 (+) | 1089 | WP_005590818.1 | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | - |
| DQM67_RS02790 (NCTC12479_00532) | - | 537506..538045 (+) | 540 | WP_005590817.1 | VanZ family protein | - |
| DQM67_RS02795 (NCTC12479_00534) | trpB | 538413..539594 (+) | 1182 | WP_005590816.1 | tryptophan synthase subunit beta | - |
| DQM67_RS02800 (NCTC12479_00535) | - | 539686..540249 (+) | 564 | WP_005590815.1 | aminodeoxychorismate/anthranilate synthase component II | - |
| DQM67_RS02805 (NCTC12479_00536) | cclA/cilC | 540238..540900 (-) | 663 | WP_005592419.1 | A24 family peptidase | Machinery gene |
| DQM67_RS02810 (NCTC12479_00537) | - | 541067..541582 (+) | 516 | WP_005592380.1 | DNA starvation/stationary phase protection protein | - |
| DQM67_RS02820 (NCTC12479_00538) | - | 541963..542181 (+) | 219 | WP_005590812.1 | YqgQ family protein | - |
| DQM67_RS02825 (NCTC12479_00539) | - | 542183..542563 (+) | 381 | WP_005590811.1 | rhodanese-like domain-containing protein | - |
| DQM67_RS10435 | - | 542502..542744 (+) | 243 | Protein_492 | DUF4190 domain-containing protein | - |
| DQM67_RS02835 (NCTC12479_00540) | - | 542780..543505 (-) | 726 | WP_005592400.1 | 16S rRNA pseudouridine(516) synthase | - |
| DQM67_RS02840 (NCTC12479_00541) | typA | 543698..545545 (+) | 1848 | WP_005590809.1 | translational GTPase TypA | - |
| DQM67_RS02845 (NCTC12479_00542) | - | 545580..545837 (+) | 258 | WP_005590808.1 | DUF3165 family protein | - |
| DQM67_RS02850 (NCTC12479_00543) | murD | 546233..547585 (+) | 1353 | WP_005592370.1 | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase | - |
| DQM67_RS02855 (NCTC12479_00544) | - | 547587..548657 (+) | 1071 | WP_005590806.1 | UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | - |
| DQM67_RS02860 (NCTC12479_00545) | - | 548654..549850 (+) | 1197 | WP_005590805.1 | cell division protein FtsQ/DivIB | - |
| DQM67_RS02865 (NCTC12479_00546) | ftsA | 549974..551338 (+) | 1365 | WP_005592428.1 | cell division protein FtsA | - |
| DQM67_RS02870 (NCTC12479_00547) | ftsZ | 551355..552620 (+) | 1266 | WP_005590803.1 | cell division protein FtsZ | - |
Sequence
Protein
Download Length: 355 a.a. Molecular weight: 38308.73 Da Isoelectric Point: 5.3084
>NTDB_id=1139493 DQM67_RS02775 WP_037586341.1 534628..535695(+) (sepM) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MTKENKRGLTVVGCAGVASIIVLVLFLFSFIVPLPYYIEVPGGAEDIRKVLTVDGKEDQAAGSYNFVTVGIQHATFAHLV
YAWLTPFTDIYSAQDMTGGSSDAEYMRINQFYMETSQNMAKYQGLKAAGKDIKMNYLGVYVLKVAPNSTFKGILNIADTV
TGVNDKTFESSEDLVKYVNSQALGDSVKVTYEEDGKTKTATGKIIKLENGKNGIGISLIDRTEVNSSVPIEFSTEGIGGP
SAGLMFSLAIYTQLANPDLRDGRVIAGTGSIDREGKVGDIGGIDKKVVSAAKIGATIFFAPDNPVSEEEKKANPKAKTNY
ETALEAAKEIKTDMKIVPVKTLQDAIDYLEKTKKS
MTKENKRGLTVVGCAGVASIIVLVLFLFSFIVPLPYYIEVPGGAEDIRKVLTVDGKEDQAAGSYNFVTVGIQHATFAHLV
YAWLTPFTDIYSAQDMTGGSSDAEYMRINQFYMETSQNMAKYQGLKAAGKDIKMNYLGVYVLKVAPNSTFKGILNIADTV
TGVNDKTFESSEDLVKYVNSQALGDSVKVTYEEDGKTKTATGKIIKLENGKNGIGISLIDRTEVNSSVPIEFSTEGIGGP
SAGLMFSLAIYTQLANPDLRDGRVIAGTGSIDREGKVGDIGGIDKKVVSAAKIGATIFFAPDNPVSEEEKKANPKAKTNY
ETALEAAKEIKTDMKIVPVKTLQDAIDYLEKTKKS
Nucleotide
Download Length: 1068 bp
>NTDB_id=1139493 DQM67_RS02775 WP_037586341.1 534628..535695(+) (sepM) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGACGAAGGAAAATAAACGTGGTTTAACAGTAGTTGGTTGTGCTGGAGTGGCCTCGATTATCGTGCTTGTGCTCTTCCT
ATTTTCTTTCATTGTTCCATTGCCTTACTATATTGAGGTGCCTGGAGGCGCAGAAGACATTCGGAAGGTTCTGACTGTGG
ACGGAAAAGAGGACCAGGCAGCAGGTTCCTATAACTTTGTAACTGTTGGAATCCAGCATGCAACCTTTGCCCACCTGGTC
TACGCTTGGCTGACGCCTTTTACGGATATTTATTCGGCTCAGGATATGACGGGTGGCTCAAGTGATGCTGAGTATATGCG
CATTAACCAATTTTATATGGAAACGTCGCAGAATATGGCCAAATATCAAGGTCTCAAAGCCGCAGGAAAAGACATCAAGA
TGAACTATCTGGGTGTCTATGTTCTAAAAGTAGCTCCGAATTCGACCTTTAAAGGAATTTTGAATATTGCGGATACGGTG
ACGGGAGTCAATGACAAGACCTTTGAAAGCTCGGAAGATTTGGTCAAATATGTCAATTCTCAGGCCTTGGGCGATAGTGT
CAAAGTGACCTACGAAGAAGATGGAAAAACCAAGACGGCGACGGGGAAAATCATCAAGCTGGAAAATGGCAAAAACGGAA
TTGGCATTAGTTTGATTGACCGCACGGAAGTCAACAGCAGTGTTCCGATTGAATTTTCGACCGAAGGCATCGGTGGTCCC
AGTGCTGGCCTCATGTTTAGCCTAGCCATCTATACTCAGCTGGCCAATCCAGACCTGCGAGACGGCCGCGTGATTGCGGG
AACGGGCAGCATTGACAGAGAGGGCAAGGTCGGTGATATTGGTGGGATTGACAAAAAAGTCGTCTCTGCTGCTAAGATCG
GAGCAACAATCTTCTTTGCTCCGGATAATCCTGTCAGCGAGGAAGAAAAAAAGGCTAATCCCAAAGCCAAGACCAACTAT
GAAACGGCGCTTGAAGCAGCTAAGGAAATCAAAACAGATATGAAAATCGTACCGGTTAAGACTCTTCAGGACGCGATTGA
TTATTTAGAAAAAACCAAAAAATCTTAG
ATGACGAAGGAAAATAAACGTGGTTTAACAGTAGTTGGTTGTGCTGGAGTGGCCTCGATTATCGTGCTTGTGCTCTTCCT
ATTTTCTTTCATTGTTCCATTGCCTTACTATATTGAGGTGCCTGGAGGCGCAGAAGACATTCGGAAGGTTCTGACTGTGG
ACGGAAAAGAGGACCAGGCAGCAGGTTCCTATAACTTTGTAACTGTTGGAATCCAGCATGCAACCTTTGCCCACCTGGTC
TACGCTTGGCTGACGCCTTTTACGGATATTTATTCGGCTCAGGATATGACGGGTGGCTCAAGTGATGCTGAGTATATGCG
CATTAACCAATTTTATATGGAAACGTCGCAGAATATGGCCAAATATCAAGGTCTCAAAGCCGCAGGAAAAGACATCAAGA
TGAACTATCTGGGTGTCTATGTTCTAAAAGTAGCTCCGAATTCGACCTTTAAAGGAATTTTGAATATTGCGGATACGGTG
ACGGGAGTCAATGACAAGACCTTTGAAAGCTCGGAAGATTTGGTCAAATATGTCAATTCTCAGGCCTTGGGCGATAGTGT
CAAAGTGACCTACGAAGAAGATGGAAAAACCAAGACGGCGACGGGGAAAATCATCAAGCTGGAAAATGGCAAAAACGGAA
TTGGCATTAGTTTGATTGACCGCACGGAAGTCAACAGCAGTGTTCCGATTGAATTTTCGACCGAAGGCATCGGTGGTCCC
AGTGCTGGCCTCATGTTTAGCCTAGCCATCTATACTCAGCTGGCCAATCCAGACCTGCGAGACGGCCGCGTGATTGCGGG
AACGGGCAGCATTGACAGAGAGGGCAAGGTCGGTGATATTGGTGGGATTGACAAAAAAGTCGTCTCTGCTGCTAAGATCG
GAGCAACAATCTTCTTTGCTCCGGATAATCCTGTCAGCGAGGAAGAAAAAAAGGCTAATCCCAAAGCCAAGACCAACTAT
GAAACGGCGCTTGAAGCAGCTAAGGAAATCAAAACAGATATGAAAATCGTACCGGTTAAGACTCTTCAGGACGCGATTGA
TTATTTAGAAAAAACCAAAAAATCTTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| sepM | Streptococcus mutans UA159 |
63.746 |
93.239 |
0.594 |