Detailed information NTG1139492

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DQM67_RS02580
• Genome accession: NZ_LS483383
• Coordinates: 501269..503542 (-)
• Length: 757 a.a.
• NCBI ID: WP_005590869.1
• Uniprot ID: A0AAV3EE01
• Organism: Streptococcus cristatus ATCC 51100 strain NCTC 12479
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 496269..508542

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM67_RS02555 (NCTC12479_00487)	-	496926..497225 (+)	300	WP_005590877.1	MGMT family protein	-
DQM67_RS02560 (NCTC12479_00488)	-	497285..498232 (+)	948	WP_005590875.1	TIGR01212 family radical SAM protein	-
DQM67_RS02565 (NCTC12479_00489)	-	498226..498774 (+)	549	WP_005590873.1	class I SAM-dependent methyltransferase	-
DQM67_RS02570 (NCTC12479_00490)	-	498822..499076 (+)	255	WP_005590872.1	hypothetical protein	-
DQM67_RS02575 (NCTC12479_00491)	-	499089..501143 (+)	2055	WP_048791894.1	sodium:proton antiporter	-
DQM67_RS02580 (NCTC12479_00492)	clpE	501269..503542 (-)	2274	WP_005590869.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQM67_RS02585 (NCTC12479_00493)	-	503784..504014 (+)	231	WP_005592360.1	DUF1797 family protein	-
DQM67_RS02590 (NCTC12479_00494)	-	504154..505008 (+)	855	WP_005590867.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
DQM67_RS02595 (NCTC12479_00495)	-	505287..505943 (+)	657	WP_005590866.1	CBS domain-containing protein	-
DQM67_RS02605 (NCTC12479_00496)	-	506195..507736 (+)	1542	WP_005592326.1	ABC-F family ATP-binding cassette domain-containing protein	-
DQM67_RS02610 (NCTC12479_00497)	-	507857..508282 (-)	426	WP_005592332.1	MarR family winged helix-turn-helix transcriptional regulator	-

Sequence

Protein

• Length: 757 a.a.
• Molecular weight: 83946.22 Da
• Isoelectric Point: 5.0185

>NTDB_id=1139492 DQM67_RS02580 WP_005590869.1 501269..503542(-) (clpE) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MLCQNCKINESTIHLYTNVNGNKQQIDLCQNCYQIMKTDPNNSLFRGLTQANNQGIDPIDDFFNSLGNFQQPQEPNPNIP
PTQSGGGYGGGGYGGNSNHGGGARQQAPQKPKGLLEEFGINVTEIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQDKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRSRQDVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTD
AAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYK
ELQKTSVLDNDIPIISEKTIEHIVEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMN
RFDGIIEFKPLSKDNLLQIVNLMLDDVNQRLATNDIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLE
NPSEKDLKAIMTSNGKILIKSAKKAEAEKTKLDESQS

Nucleotide

• Length: 2274 bp

>NTDB_id=1139492 DQM67_RS02580 WP_005590869.1 501269..503542(-) (clpE) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGCTTTGTCAAAATTGTAAAATCAATGAATCAACCATCCATCTCTATACAAATGTAAACGGAAATAAACAGCAGATTGA
CCTTTGTCAAAACTGCTATCAAATCATGAAGACAGACCCTAACAATAGCCTTTTTCGAGGACTGACTCAGGCTAACAACC
AAGGAATTGATCCTATTGACGATTTCTTTAACAGTCTTGGTAATTTTCAACAACCCCAAGAACCAAATCCAAATATCCCG
CCAACTCAATCTGGAGGAGGCTACGGTGGCGGTGGCTATGGTGGCAATTCCAATCATGGAGGCGGAGCACGCCAACAGGC
TCCGCAAAAGCCAAAAGGTCTCCTAGAAGAGTTTGGTATCAATGTGACTGAGATCGCCCGTAAAGGAGAAATTGACCCTG
TCATCGGTCGGGACGAAGAGATTACTCGTGTCATTGAAATCCTCAACCGCCGCACCAAGAACAATCCTGTCCTTATCGGG
GAACCCGGTGTCGGAAAAACAGCCGTGGTCGAAGGCTTGGCCCAGAAGATTGTTGATGGTGATGTACCTCATAAACTCCA
AGACAAGGAAGTTATCCGCCTAGACGTTGTCAGCCTAGTACAAGGGACTGGTATCCGTGGTCAATTTGAAGAGCGGATGC
AGAAGCTCATGGACGAGATTCGTTCTCGTCAAGATGTCATTCTCTTTATTGATGAAATCCATGAAATCGTAGGAGCTGGA
TCTGCTGGCGATGGCAATATGGACGCTGGAAATATCCTCAAACCAGCTTTGGCTCGCGGAGAACTCCAAATGGTTGGGGC
TACTACCCTCAATGAATACCGTATCATTGAGAAGGATGCTGCCCTCGAGCGCCGCATGCAGCCCGTTAAGGTCGACGAGC
CAACAGTAGAGGAAACGATTACCATCCTCAAAGGGATTCAGAAAAAATACGAAGACTACCATCATGTCAAGTACACAGAC
GCGGCCATTGAAGCTGCGGCACTTCTCTCCAACCGCTACATCCAAGATCGCTTCCTGCCAGACAAGGCTATCGACCTCTT
GGATGAGGCTGGTTCTAAGATGAATCTGACCCTCAACTTTGTTGATCCCAAGGTCATTGACCAGCGTCTTATTGAGGCCG
AAAACCTCAAGGCTCAGGCAACCCGTGACGAAGATTTCGAGAAGGCGGCTTACTTCCGTGACCAGATTGCCAAATACAAG
GAACTTCAGAAGACGAGCGTGCTGGATAACGATATCCCAATTATCAGCGAGAAAACGATTGAGCACATCGTAGAGCAAAA
GACCAATATTCCAGTTGGCGATCTCAAAGAAAAGGAACAGTCTCAACTAATCAATCTCGCTAGCGACTTAAAGGCTCATG
TCATCGGCCAAGATGATGCCGTGGATAAGATTGCCAAGGCCATCCGCCGCAACCGGGTCGGACTAGGAAGTCCTAATCGC
CCAATCGGAAGCTTCCTCTTTGTCGGCCCAACTGGTGTCGGTAAGACTGAGCTGTCTAAGCAACTAGCCATTGAGCTCTT
TGGCTCGGCTGACAGCATGATTCGCTTTGATATGAGTGAATATATGGAGAAACACAGCGTGGCCAAGCTGGTCGGTGCGC
CTCCAGGCTACGTCGGATACGAGGAAGCGGGTCAGTTGACTGAGCGCGTCCGTCGCAATCCCTACTCGCTCATTCTGTTG
GATGAGGTAGAAAAGGCCCATCCTGATGTCATGCATATGTTCCTGCAGGTTCTGGATGATGGCCGCCTGACCGATGGTCA
AGGTCGGACTGTCAGCTTCAAGGACACCATTATCATCATGACATCCAATGCCGGAACTGGCAAAGCTGAAGCCAGCGTTG
GCTTTGGGGCAGCTCGTGAAGGCCGTACCAATTCCGTCTTGGGTGAATTGGGCAACTTCTTCAGTCCTGAGTTTATGAAC
CGCTTTGACGGCATTATCGAATTCAAGCCACTCAGCAAGGACAACCTGCTGCAAATCGTCAACCTTATGCTGGACGATGT
TAATCAACGTTTGGCAACCAATGACATTCATCTGGATGTTACGGAGAAGGTCAAGGAAAAATTGGTTGACCTAGGCTACG
ATCCAAAAATGGGCGCTCGCCCACTGCGCCGTACCATTCAGGATCATATCGAAGATGCTATTACTGACTTTTATCTGGAA
AATCCAAGCGAAAAAGATCTCAAAGCTATCATGACTAGCAATGGAAAAATTCTCATCAAATCAGCCAAAAAGGCTGAAGC
AGAAAAAACCAAGCTCGATGAAAGCCAAAGCTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• AAA lid domain (AAA_lid_9) (295-392)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-276)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	87.35	99.207	0.867
clpE	Streptococcus pneumoniae D39	87.35	99.207	0.867
clpE	Streptococcus pneumoniae R6	87.35	99.207	0.867
clpE	Streptococcus pneumoniae TIGR4	87.217	99.207	0.865
clpE	Streptococcus mutans UA159	85.314	98.943	0.844
clpC	Lactococcus lactis subsp. cremoris KW2	76.494	99.472	0.761
clpC	Bacillus subtilis subsp. subtilis str. 168	51.484	89.036	0.458
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.32	82.563	0.399
clpC	Streptococcus pneumoniae Rx1	47.917	82.431	0.395
clpC	Streptococcus pneumoniae D39	47.917	82.431	0.395
clpC	Streptococcus thermophilus LMD-9	47.68	82.563	0.394
clpC	Streptococcus pneumoniae TIGR4	47.756	82.431	0.394
clpC	Streptococcus thermophilus LMG 18311	47.36	82.563	0.391
clpC	Streptococcus mutans UA159	47.125	82.695	0.39