Detailed information NTG1139467

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM89_RS07435
• Genome accession: NZ_LS483382
• Coordinates: 1422528..1423253 (-)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC13738
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 1417528..1428253

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM89_RS07400 (NCTC13738_01478)	-	1417662..1418045 (+)	384	WP_002988673.1	ImmA/IrrE family metallo-endopeptidase	-
DQM89_RS07405 (NCTC13738_01479)	-	1418056..1418607 (+)	552	WP_002988670.1	hypothetical protein	-
DQM89_RS07410 (NCTC13738_01480)	-	1418724..1419803 (+)	1080	WP_002988667.1	site-specific integrase	-
DQM89_RS07420 (NCTC13738_01482)	trmB	1420001..1420636 (-)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM89_RS07425 (NCTC13738_01483)	ccrZ	1420636..1421427 (-)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM89_RS07430 (NCTC13738_01484)	-	1421491..1422525 (-)	1035	WP_076634067.1	ABC transporter permease	-
DQM89_RS07435 (NCTC13738_01485)	pptA	1422528..1423253 (-)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM89_RS07440 (NCTC13738_01486)	-	1423325..1423744 (+)	420	WP_076634066.1	HIT family protein	-
DQM89_RS07445 (NCTC13738_01487)	-	1423741..1424097 (+)	357	WP_002988657.1	hypothetical protein	-
DQM89_RS07450 (NCTC13738_01488)	brpA	1424208..1425491 (-)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM89_RS07455 (NCTC13738_01489)	-	1425500..1426024 (-)	525	WP_076634065.1	GNAT family N-acetyltransferase	-
DQM89_RS07460 (NCTC13738_01490)	tsaE	1425999..1426460 (-)	462	WP_009880751.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM89_RS07465 (NCTC13738_01491)	-	1426614..1428074 (-)	1461	WP_023079950.1	NCS2 family permease	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1139467 DQM89_RS07435 WP_002983379.1 1422528..1423253(-) (pptA) [Streptococcus pyogenes strain NCTC13738]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1139467 DQM89_RS07435 WP_002983379.1 1422528..1423253(-) (pptA) [Streptococcus pyogenes strain NCTC13738]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCTTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGTTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714