Detailed information NTG1139461

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM89_RS06355
• Genome accession: NZ_LS483382
• Coordinates: 1217796..1218833 (-)
• Length: 345 a.a.
• NCBI ID: WP_012560824.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC13738
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1212796..1223833

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM89_RS06335 (NCTC13738_01264)	-	1213546..1214172 (+)	627	WP_002983834.1	prepilin peptidase	-
DQM89_RS06340 (NCTC13738_01265)	rlmN	1214254..1215333 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM89_RS06345 (NCTC13738_01266)	-	1215337..1215957 (-)	621	WP_032464468.1	YutD family protein	-
DQM89_RS06350 (NCTC13738_01267)	-	1216405..1217382 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
DQM89_RS06355 (NCTC13738_01268)	sepM	1217796..1218833 (-)	1038	WP_012560824.1	SepM family pheromone-processing serine protease	Regulator
DQM89_RS06360 (NCTC13738_01269)	coaD	1218820..1219311 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQM89_RS06365 (NCTC13738_01270)	rsmD	1219301..1219840 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM89_RS06370 (NCTC13738_01271)	asnA	1219963..1220955 (-)	993	WP_012560825.1	aspartate--ammonia ligase	-
DQM89_RS06375 (NCTC13738_01272)	arcC	1221268..1222218 (-)	951	WP_076634519.1	carbamate kinase	-
DQM89_RS06380 (NCTC13738_01273)	-	1222238..1223569 (-)	1332	WP_011285641.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37541.20 Da
• Isoelectric Point: 9.5788

>NTDB_id=1139461 DQM89_RS06355 WP_012560824.1 1217796..1218833(-) (sepM) [Streptococcus pyogenes strain NCTC13738]
MKRLNKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPITTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1139461 DQM89_RS06355 WP_012560824.1 1217796..1218833(-) (sepM) [Streptococcus pyogenes strain NCTC13738]
ATGAAAAGACTTAACAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTATTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-309)

• PDZ domain (PDZ_2) (129-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.696	100	0.687