Detailed information NTG1139328

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DQM75_RS03005
• Genome accession: NZ_LS483380
• Coordinates: 610970..613225 (-)
• Length: 751 a.a.
• NCBI ID: WP_111692287.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11824
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 605970..618225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM75_RS02990 (NCTC11824_00597)	ileS	606744..609542 (+)	2799	WP_111692286.1	isoleucine--tRNA ligase	-
DQM75_RS02995 (NCTC11824_00598)	-	610012..610314 (-)	303	WP_012515246.1	DUF1827 family protein	-
DQM75_RS03000 (NCTC11824_00599)	-	610376..610822 (-)	447	WP_043025456.1	NUDIX hydrolase	-
DQM75_RS03005 (NCTC11824_00600)	clpE	610970..613225 (-)	2256	WP_111692287.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQM75_RS03010 (NCTC11824_00601)	-	613508..613738 (+)	231	WP_012515249.1	DUF1797 family protein	-
DQM75_RS03015 (NCTC11824_00602)	-	614183..615580 (-)	1398	WP_111692288.1	LPXTG cell wall anchor domain-containing protein	-
DQM75_RS03020 (NCTC11824_00603)	-	615936..616619 (+)	684	WP_111692289.1	amino acid ABC transporter permease	-
DQM75_RS03025 (NCTC11824_00604)	-	616621..617358 (+)	738	WP_111692290.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83845.23 Da
• Isoelectric Point: 5.6718

>NTDB_id=1139328 DQM75_RS03005 WP_111692287.1 610970..613225(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKAQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDTPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKDLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=1139328 DQM75_RS03005 WP_111692287.1 610970..613225(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGCTTTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCGG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAGGAAATCCGCAAGCGCCATGACGTTATCCTTTTTATTGATGAAATCCATGAAATTGTGGGAGCCGGG
GCAGTTGGTGATGGCAGTATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
GACCACTCTCAATGAATACCGCATCATCGAAAAGGACGCAGCCCTTGAGCGACGCATGCAGCCGGTTAAGGTGGATGAGC
CTTCGGTTGAAGAAACAATCACTATCCTAAAAGGAATCCAACCCAAATATGAGGACTATCATCATGTCAAATATAGCCAG
TCGGCTATTGAAGCAGCTGCTAACCTCTCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTGCT
AGATGAAGCCGGCTCAAAGATGAACCTAACCCTTAACTTTGTTGACCCCAAAGACATTGATAAGCGTTTGATTGAGGCAG
AAAACCTTAAGGCACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTACTTCCGCGATCAAATCGCCAAATACAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATACTCCAATCATTACCGATAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCTGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGACGCCGTTGATAAAATTGCTAAGGCTATCCGTCGTAATCGTGTTGGACTTGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGCCCAACTGGTGTCGGTAAAACAGAGCTTTCCAAGCAATTAGCCATTGAGCTTTT
TGGCTCTGCTGATAACATGATTCGCTTTGACATGTCTGAATACATGGAAAAGCACGCTGTGGCTAAGCTTGTCGGTGCCC
CTCCCGGCTACGTCGGCTATGAGGAGGCAGGTCAGTTAACAGAGCAGGTGCGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATCGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGACGATTAACCGACGGACA
AGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAGGCCTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAACTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGCCCCGAGTTCATGAAT
CGCTTTGATGGCATTATTGAGTTTCAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGACGCCATTACTGACTTCTACCTTGAG
CACCCAGCAGAAAAAGACCTGCGAGCTGTCTTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (295-392)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-725)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.636	98.802	0.836
clpE	Streptococcus pneumoniae Rx1	82.626	100	0.83
clpE	Streptococcus pneumoniae D39	82.626	100	0.83
clpE	Streptococcus pneumoniae R6	82.626	100	0.83
clpE	Streptococcus pneumoniae TIGR4	82.493	100	0.828
clpC	Lactococcus lactis subsp. cremoris KW2	75.399	100	0.755
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.04	85.486	0.402
clpC	Streptococcus pneumoniae Rx1	48.052	82.024	0.394
clpC	Streptococcus pneumoniae D39	48.052	82.024	0.394
clpC	Streptococcus pneumoniae TIGR4	47.89	82.024	0.393
clpC	Streptococcus thermophilus LMD-9	46.667	83.888	0.391
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMG 18311	46.349	83.888	0.389