Detailed information NTG1139327

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM75_RS02890
• Genome accession: NZ_LS483380
• Coordinates: 586922..587959 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC11824
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 581922..592959

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM75_RS02865 (NCTC11824_00572)	-	582235..583566 (+)	1332	WP_043025442.1	dipeptidase	-
DQM75_RS02870 (NCTC11824_00573)	arcC	583584..584534 (+)	951	WP_111689942.1	carbamate kinase	-
DQM75_RS02875 (NCTC11824_00574)	asnA	584754..585746 (+)	993	WP_012515219.1	aspartate--ammonia ligase	-
DQM75_RS02880 (NCTC11824_00575)	rsmD	585915..586454 (+)	540	WP_111692279.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM75_RS02885 (NCTC11824_00576)	coaD	586444..586944 (+)	501	WP_111692280.1	pantetheine-phosphate adenylyltransferase	-
DQM75_RS02890 (NCTC11824_00577)	sepM	586922..587959 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
DQM75_RS02895 (NCTC11824_00578)	-	588579..589193 (+)	615	WP_111692281.1	YutD family protein	-
DQM75_RS02900 (NCTC11824_00579)	rlmN	589197..590279 (+)	1083	WP_043029472.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM75_RS02905 (NCTC11824_00580)	-	590702..591151 (-)	450	WP_228269161.1	peptidase	-
DQM75_RS02910 (NCTC11824_00581)	-	591551..592081 (+)	531	WP_012515230.1	Dps family protein	-
DQM75_RS02915 (NCTC11824_00582)	-	592455..592688 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=1139327 DQM75_RS02890 WP_014622492.1 586922..587959(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=1139327 DQM75_RS02890 WP_014622492.1 586922..587959(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTAGTGAGCCTCAGTCGGGCCACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGACTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTATCAGGCCCTTACTCTAGCAGGCAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTATCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701