Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQM75_RS00840 Genome accession   NZ_LS483380
Coordinates   147528..149969 (+) Length   813 a.a.
NCBI ID   WP_111692106.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC11824     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 142528..154969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM75_RS00810 (NCTC11824_00162) rpsB 142918..143688 (-) 771 WP_111692104.1 30S ribosomal protein S2 -
  DQM75_RS00815 (NCTC11824_00163) ahpF 143948..145480 (-) 1533 WP_111692105.1 alkyl hydroperoxide reductase subunit F -
  DQM75_RS00820 (NCTC11824_00164) ahpC 145501..146061 (-) 561 WP_012514798.1 alkyl hydroperoxide reductase subunit C -
  DQM75_RS00830 - 146694..146897 (+) 204 WP_012514799.1 cold-shock protein -
  DQM75_RS00835 (NCTC11824_00167) - 147067..147528 (+) 462 WP_012677252.1 CtsR family transcriptional regulator -
  DQM75_RS00840 (NCTC11824_00168) clpC 147528..149969 (+) 2442 WP_111692106.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM75_RS00845 - 150319..150465 (-) 147 WP_080312399.1 putative holin-like toxin -
  DQM75_RS00850 (NCTC11824_00171) - 150746..151177 (+) 432 WP_111692107.1 hypothetical protein -
  DQM75_RS00855 (NCTC11824_00173) - 151312..151734 (+) 423 WP_012677254.1 hypothetical protein -
  DQM75_RS00860 (NCTC11824_00175) - 151963..152394 (+) 432 WP_012677255.1 hypothetical protein -
  DQM75_RS00865 (NCTC11824_00176) - 152396..153685 (+) 1290 WP_111692108.1 hypothetical protein -
  DQM75_RS00870 (NCTC11824_00177) - 153667..154059 (+) 393 WP_043029278.1 hypothetical protein -
  DQM75_RS00875 (NCTC11824_00178) - 154040..154330 (+) 291 WP_038674620.1 hypothetical protein -
  DQM75_RS00880 (NCTC11824_00179) groES 154630..154917 (+) 288 WP_111692109.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90410.26 Da        Isoelectric Point: 6.4367

>NTDB_id=1139319 DQM75_RS00840 WP_111692106.1 147528..149969(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSKLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAIGHDHQTMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAALAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQSLK
IGVSRGKLAFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1139319 DQM75_RS00840 WP_111692106.1 147528..149969(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC11824]
GTGATGATTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAAGCAGAGCGCTTTGATAGTCCTTACCT
TGAGACCTGGCATATTTTATTAGCTATGGTAGCTGTTGACCATTCCTTAGCGGCCATGGTGTTAAGCGAATTTGAACGAA
AGATTAGGGCTGAAGAGTATGAGGCTGCTGCTATTTTAGCCATGGGAAAAAGTCCCAAAGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTACTCTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTCTGTTAGAGTTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGCAAAATCATCTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACTCTTGATGCAGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGTGCTACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAGGACGCAGCCCTTTCTCGTCGCTTTGCCAAAATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTGTCCATACTGCTGTGAAGCTGGCTCGGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACACCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAAGCTATCAGGTATTCCCCTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
GAATCTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ACCAGTCAGGCATTCGCACAGGCAGGCGTCCGATTGGCTCCTTTATGTTTCTTGGTCCAACTGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGATATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCCCGTCTTAATGGGGCTCCTCCTGGCTATGTTGGCTATGATGAGGGAGGAGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCGGTCATGACCATCAAACAATGGAAA
AGCGTATTTTGGAGGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAGAAGGTGGTTTTCCATAGC
CTAACACAGGAAAACATGCGTGATGTGGTGAAAATTATGGTTAAGCCGCTGATTGCAGCCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTGTCTGAAGCTGGTTACGATGTTGAAATGGGCGCTCGCCCACTTCGTC
GCACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGAGTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGCTAGCTTTTGATATCGCTTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA lid domain (AAA_lid_9)

(374-457)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(95-131)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-51)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

74.785

100

0.748
  clpC Streptococcus thermophilus LMD-9

72.181

100

0.724
  clpC Streptococcus thermophilus LMG 18311

71.936

100

0.722
  clpC Streptococcus pneumoniae Rx1

65.848

100

0.659
  clpC Streptococcus pneumoniae D39

65.848

100

0.659
  clpC Streptococcus pneumoniae TIGR4

65.725

100

0.658
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.623

100

0.499
  clpC Bacillus subtilis subsp. subtilis str. 168

43.832

100

0.45
  clpE Streptococcus mutans UA159

45.511

79.459

0.362

Multiple sequence alignment