Detailed information NTG1139292

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM61_RS06070
• Genome accession: NZ_LS483379
• Coordinates: 1177872..1178909 (-)
• Length: 345 a.a.
• NCBI ID: WP_023610142.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10874
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1172872..1183909

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM61_RS06045 (NCTC10874_01199)	-	1172876..1173403 (-)	528	WP_002983837.1	Dps family protein	-
DQM61_RS06050 (NCTC10874_01200)	-	1173631..1174257 (+)	627	WP_002983834.1	prepilin peptidase	-
DQM61_RS06055 (NCTC10874_01201)	rlmN	1174339..1175418 (-)	1080	WP_002992788.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM61_RS06060 (NCTC10874_01202)	-	1175422..1176042 (-)	621	WP_002992791.1	YutD family protein	-
DQM61_RS06065 (NCTC10874_01203)	-	1176490..1177467 (-)	978	WP_002994809.1	LacI family DNA-binding transcriptional regulator	-
DQM61_RS06070 (NCTC10874_01204)	sepM	1177872..1178909 (-)	1038	WP_023610142.1	SepM family pheromone-processing serine protease	Regulator
DQM61_RS06075 (NCTC10874_01205)	coaD	1178896..1179387 (-)	492	WP_002983821.1	pantetheine-phosphate adenylyltransferase	-
DQM61_RS06080 (NCTC10874_01206)	rsmD	1179377..1179916 (-)	540	WP_002983819.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM61_RS06085 (NCTC10874_01207)	asnA	1180039..1181031 (-)	993	WP_002994813.1	aspartate--ammonia ligase	-
DQM61_RS06090 (NCTC10874_01208)	arcC	1181344..1182294 (-)	951	WP_002994815.1	carbamate kinase	-
DQM61_RS06095 (NCTC10874_01209)	-	1182314..1183645 (-)	1332	WP_011054719.1	dipeptidase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37544.26 Da
• Isoelectric Point: 9.5788

>NTDB_id=1139292 DQM61_RS06070 WP_023610142.1 1177872..1178909(-) (sepM) [Streptococcus pyogenes strain NCTC10874]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDMEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide

• Length: 1038 bp

>NTDB_id=1139292 DQM61_RS06070 WP_023610142.1 1177872..1178909(-) (sepM) [Streptococcus pyogenes strain NCTC10874]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATATGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-306)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	68.986	100	0.69