Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB/nlmE   Type   Regulator
Locus tag   DQM97_RS09250 Genome accession   NZ_LS483378
Coordinates   1887951..1888874 (-) Length   307 a.a.
NCBI ID   WP_002961554.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC12279     
Function   transport of ComC (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1886801..1887469 1887951..1888874 flank 482


Gene organization within MGE regions


Location: 1886801..1888874
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM97_RS09245 (NCTC12279_01862) - 1886801..1887789 (-) 989 Protein_1756 IS30 family transposase -
  DQM97_RS09250 (NCTC12279_01863) comB/nlmE 1887951..1888874 (-) 924 WP_002961554.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator

Sequence

Protein


Download         Length: 307 a.a.        Molecular weight: 35187.78 Da        Isoelectric Point: 10.3331

>NTDB_id=1139243 DQM97_RS09250 WP_002961554.1 1887951..1888874(-) (comB/nlmE) [Streptococcus sobrinus strain NCTC12279]
MNPKLLESAEFYRRRYHNFATVLIVPLVILIIFIGVFLCFAKKEITVISQGEVAPTKVLAVIQSVSDTSIAQNKLDDNTK
VDKGDLLVQYTENAEPEQKDAQKNTIKDRNDRLDKEIEKEEKKTKKKYKKLSKKERKKREKKDQKKKEKKKKDRDSEDKK
ETDHVSLFAPESGVIHTNSKYDGLNILPKWSEIAQIYPDIQKTKTVLITYYVSSDDVVSMKKGQTTRLSLEKKGNDKLTV
QGKINSVAASATTTKKGNLFKVTAKVKLSKKDSKLVKYGMTGKTVTVIDKKTYFDYFKDKLLHKVED

Nucleotide


Download         Length: 924 bp        

>NTDB_id=1139243 DQM97_RS09250 WP_002961554.1 1887951..1888874(-) (comB/nlmE) [Streptococcus sobrinus strain NCTC12279]
ATGAATCCAAAATTACTTGAAAGTGCGGAATTTTACCGTCGTCGCTACCATAATTTTGCGACTGTTCTTATTGTGCCCTT
GGTTATCTTGATTATCTTCATTGGTGTTTTCCTCTGCTTTGCCAAAAAGGAAATCACAGTGATTTCTCAAGGTGAAGTGG
CGCCAACAAAGGTATTGGCCGTTATCCAGTCTGTTAGTGACACATCGATTGCACAAAATAAATTAGACGACAACACTAAG
GTTGATAAGGGTGACCTCTTGGTGCAGTACACAGAGAATGCGGAACCAGAACAAAAGGATGCCCAAAAGAATACAATCAA
GGACCGCAATGACCGCCTAGACAAGGAAATAGAAAAGGAAGAGAAGAAAACAAAGAAAAAGTATAAAAAGCTTTCCAAAA
AGGAAAGGAAGAAACGGGAGAAAAAAGACCAGAAGAAGAAGGAGAAAAAGAAAAAAGACCGAGATTCAGAGGATAAAAAA
GAAACAGACCACGTTTCCCTCTTTGCTCCTGAGTCAGGAGTGATCCATACTAACAGTAAGTATGATGGCCTCAATATCCT
TCCTAAGTGGTCAGAAATTGCCCAAATCTATCCTGATATTCAAAAGACGAAAACCGTCTTAATTACCTACTACGTCTCAT
CTGACGATGTTGTTTCCATGAAGAAGGGCCAAACGACCCGTTTATCGCTTGAAAAGAAAGGCAATGATAAACTGACCGTC
CAAGGGAAAATCAATAGTGTCGCTGCATCGGCCACGACGACCAAGAAGGGCAACCTCTTCAAGGTCACAGCCAAGGTCAA
GCTGTCCAAGAAGGACAGCAAGCTGGTCAAGTATGGGATGACTGGAAAGACAGTCACCGTTATTGATAAGAAGACCTACT
TCGATTACTTCAAGGATAAATTGCTTCACAAGGTGGAGGATTAA

Domains

Predicted by InterproScan.

HlyD family secretion protein (HlyD_3)

(167-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB/nlmE Streptococcus mutans UA159

68.404

100

0.684

Multiple sequence alignment