Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DQM54_RS03380 Genome accession   NZ_LS483375
Coordinates   688079..690310 (-) Length   743 a.a.
NCBI ID   WP_111723429.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 683079..695310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS03350 (NCTC3165_00666) - 684481..684936 (-) 456 WP_111723425.1 MarR family winged helix-turn-helix transcriptional regulator -
  DQM54_RS03355 (NCTC3165_00667) - 684959..685396 (+) 438 WP_082307108.1 GNAT family N-acetyltransferase -
  DQM54_RS03360 (NCTC3165_00668) - 685433..685732 (-) 300 WP_045773849.1 DUF1827 family protein -
  DQM54_RS03365 (NCTC3165_00669) - 685831..686283 (-) 453 WP_111723426.1 NUDIX hydrolase -
  DQM54_RS03370 (NCTC3165_00670) - 686443..687333 (+) 891 WP_111723427.1 helix-turn-helix transcriptional regulator -
  DQM54_RS03375 (NCTC3165_00671) - 687393..687998 (+) 606 WP_111723428.1 GyrI-like domain-containing protein -
  DQM54_RS03380 (NCTC3165_00672) clpE 688079..690310 (-) 2232 WP_111723429.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM54_RS03385 (NCTC3165_00673) - 690563..690793 (+) 231 WP_008809091.1 DUF1797 family protein -
  DQM54_RS03390 (NCTC3165_00674) - 690927..691781 (+) 855 WP_111723430.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  DQM54_RS03395 (NCTC3165_00675) - 691778..692551 (+) 774 WP_111723431.1 HAD hydrolase family protein -
  DQM54_RS03400 (NCTC3165_00676) - 692659..693501 (+) 843 WP_111723432.1 NAD(P)H-hydrate dehydratase -
  DQM54_RS03410 (NCTC3165_00677) xseA 693656..694996 (+) 1341 WP_111723433.1 exodeoxyribonuclease VII large subunit -
  DQM54_RS03415 (NCTC3165_00678) - 694974..695186 (+) 213 WP_008809086.1 exodeoxyribonuclease VII small subunit -

Sequence

Protein


Download         Length: 743 a.a.        Molecular weight: 82875.96 Da        Isoelectric Point: 5.0200

>NTDB_id=1139110 DQM54_RS03380 WP_111723429.1 688079..690310(-) (clpE) [Streptococcus gordonii strain NCTC3165]
MLCQNCKINESTIHLYTNVNGKKQQVDLCQNCYQIMKTDPNNSLLGGLTNMNNHNMDPFDDFFNHLGNFQGPKDSTPPTQ
SGGSYGGGNYGPGSNNQRPQSASNKPKGLLEEFGINVTEIARRGDIDPVIGRDDEIRRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPQKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRNRNDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVRYTDEAIEA
AAILSNRYIQDRFLPDKAIDLLDESGSKMNLTLNFVDPKEIDRRLIEAENLKTQATRDEDYEKAAYFRDQIAKYKEMQTA
KIDEQDTPIISEKEIEAIVEQKTNIPVGDLKEKEQSQLIHLASDLKSHVIGQDDAVDKIAKAIRRNRVGLGSPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKALSKDNLLQIVDLMLEDVNNRLASNEIHLDVTTKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLEHPTDK
DLKAIMTSNGKIIIKGKQKAELD

Nucleotide


Download         Length: 2232 bp        

>NTDB_id=1139110 DQM54_RS03380 WP_111723429.1 688079..690310(-) (clpE) [Streptococcus gordonii strain NCTC3165]
ATGCTTTGTCAAAACTGTAAAATCAATGAATCTACCATTCATTTATACACTAATGTAAATGGTAAAAAACAACAAGTCGA
CCTCTGTCAAAATTGCTATCAGATTATGAAAACTGATCCAAATAACTCTCTTTTGGGTGGACTAACGAACATGAATAATC
ATAATATGGATCCTTTTGATGATTTCTTTAATCATCTGGGGAATTTCCAAGGGCCGAAGGATTCTACCCCTCCAACTCAA
TCAGGTGGTAGTTATGGAGGGGGCAACTATGGTCCTGGTTCTAATAACCAGCGTCCTCAGTCAGCCTCCAATAAACCAAA
AGGTCTTTTGGAAGAGTTTGGTATTAACGTTACAGAAATTGCTCGACGTGGTGATATTGATCCAGTGATTGGACGAGATG
ATGAAATTCGTCGTGTTATAGAAATTCTCAATCGCCGAACTAAGAACAATCCAGTCCTTATCGGTGAACCTGGTGTCGGA
AAGACTGCTGTTGTGGAGGGCTTGGCTCAAAAAATAGTCGACGGTGATGTTCCTCAAAAATTGCAAGGAAAAGAGGTCAT
TCGGCTCGATGTTGTCAGCCTTGTTCAAGGAACTGGTATTCGCGGGCAATTTGAAGAACGAATGCAAAAACTCATGGATG
AGATTCGCAATCGCAATGATATCATTCTCTTTATTGATGAAATCCATGAAATTGTTGGAGCTGGTTCTGCGGGCGATGGG
AACATGGATGCTGGAAATATTCTCAAACCTGCTCTTGCTCGAGGTGAACTTCAACTGGTTGGAGCTACTACTCTCAATGA
ATATCGTATCATTGAAAAAGATGCAGCTTTAGAAAGACGGATGCAACCAGTCAAAGTAGATGAACCAACCGTAGAAGAAA
CGATCACAATTCTAAAGGGAATTCAAAAGAAATACGAAGATTACCACCATGTTCGCTACACAGATGAAGCTATTGAAGCT
GCTGCCATCCTATCCAATCGTTATATTCAGGACCGTTTCCTTCCCGATAAAGCTATTGATCTTTTGGATGAATCAGGATC
TAAGATGAACCTAACCCTCAATTTTGTTGATCCAAAAGAAATTGACAGACGCTTGATAGAGGCTGAAAATCTGAAAACAC
AGGCCACTCGCGATGAAGATTACGAAAAAGCAGCCTACTTCCGCGACCAAATTGCCAAATATAAGGAAATGCAAACTGCT
AAAATAGATGAACAAGATACTCCTATCATCAGTGAGAAGGAGATCGAAGCTATTGTCGAGCAAAAAACAAATATTCCTGT
TGGGGATTTGAAGGAAAAAGAGCAGTCTCAGCTTATTCATTTAGCCAGTGATTTGAAGTCTCATGTCATTGGGCAGGATG
ATGCTGTTGATAAGATTGCAAAAGCCATCCGTCGTAATCGTGTGGGATTAGGCAGTCCAAACCGGCCAATCGGAAGTTTC
CTTTTTGTTGGACCGACAGGCGTTGGAAAAACTGAACTTTCCAAACAATTGGCCATCGAACTTTTTGGCTCTGCCGATAG
CATGATTCGTTTTGATATGAGTGAATACATGGAAAAACATAGCGTTGCCAAACTTGTGGGAGCACCTCCAGGCTACGTTG
GCTATGAAGAAGCAGGCCAGTTGACTGAACGTGTTCGTCGTAATCCATACTCACTCATTCTCCTAGATGAGGTGGAAAAA
GCTCATCCAGATGTCATGCATATGTTCTTACAAGTCCTAGATGATGGACGTTTGACTGATGGTCAAGGCAGGACAGTCAG
CTTCAAAGATACCATTATTATCATGACTTCCAATGCAGGAACTGGCAAAGTGGAAGCTAGCGTTGGCTTTGGTGCTGCTC
GAGAAGGTCGGACAAATTCTGTCTTAGGTGAGTTAGGTAACTTCTTTAGTCCAGAATTCATGAATCGATTTGATGGTATC
ATTGAATTCAAGGCATTAAGCAAGGATAATCTCTTACAGATTGTGGATCTAATGCTGGAAGATGTTAATAATCGACTCGC
TAGCAACGAAATTCATCTAGATGTAACAACTAAAGTCAAAGAAAAATTGGTTGATCTGGGCTACGATCCTAAGATGGGGG
CACGACCACTCCGTAGAACTATTCAGGATTATATCGAAGATGCTATTACGGACTACTACCTAGAACATCCGACAGATAAG
GATTTAAAAGCAATTATGACTAGCAATGGCAAGATTATAATTAAGGGTAAACAAAAAGCTGAGCTTGATTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

AAA lid domain (AAA_lid_9)

(290-387)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-718)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

86.997

100

0.873
  clpE Streptococcus pneumoniae D39

86.997

100

0.873
  clpE Streptococcus pneumoniae R6

86.997

100

0.873
  clpE Streptococcus pneumoniae TIGR4

86.863

100

0.872
  clpE Streptococcus mutans UA159

85.121

100

0.855
  clpC Lactococcus lactis subsp. cremoris KW2

78.273

99.731

0.781
  clpC Bacillus subtilis subsp. subtilis str. 168

50.444

90.983

0.459
  clpC Streptococcus pneumoniae Rx1

47.84

84.118

0.402
  clpC Streptococcus pneumoniae D39

47.84

84.118

0.402
  clpC Streptococcus pneumoniae TIGR4

47.68

84.118

0.401
  clpC Streptococcus thermophilus LMD-9

45.137

88.56

0.4
  clpC Streptococcus mutans UA159

46.406

86.137

0.4
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

46.761

85.195

0.398
  clpC Streptococcus thermophilus LMG 18311

44.833

88.56

0.397

Multiple sequence alignment