Detailed information NTG1138890

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DQM56_RS03270
• Genome accession: NZ_LS483368
• Coordinates: 663265..665520 (-)
• Length: 751 a.a.
• NCBI ID: WP_111710432.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 658265..670520

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS03255 (NCTC6176_00654)	ileS	659038..661836 (+)	2799	WP_111710430.1	isoleucine--tRNA ligase	-
DQM56_RS03260 (NCTC6176_00655)	-	662307..662609 (-)	303	WP_012515246.1	DUF1827 family protein	-
DQM56_RS03265 (NCTC6176_00656)	-	662671..663117 (-)	447	WP_111710431.1	NUDIX hydrolase	-
DQM56_RS03270 (NCTC6176_00657)	clpE	663265..665520 (-)	2256	WP_111710432.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQM56_RS03275 (NCTC6176_00658)	-	665801..666031 (+)	231	WP_012515249.1	DUF1797 family protein	-
DQM56_RS03280 (NCTC6176_00659)	-	666476..667774 (-)	1299	WP_111710433.1	LPXTG cell wall anchor domain-containing protein	-
DQM56_RS03285 (NCTC6176_00660)	-	668120..668803 (+)	684	WP_043029481.1	amino acid ABC transporter permease	-
DQM56_RS03290 (NCTC6176_00661)	-	668805..669542 (+)	738	WP_012515254.1	amino acid ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 751 a.a.
• Molecular weight: 83860.29 Da
• Isoelectric Point: 5.7717

>NTDB_id=1138890 DQM56_RS03270 WP_111710432.1 663265..665520(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPILGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLP
NTPPTQSGGQHGGGHNGGYRPNQTQPTQEASKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKRHDVILFIDEIHEIVGAG
AVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQAKYEDYHHVKYSQ
SAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFRDQIAKYK
EMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLKKHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILL
DEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSHFFSPEFMN
RFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQKVKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLE
HPAEKNLRAVLTSNGHIIIKPVVKSQAKQAD

Nucleotide

• Length: 2256 bp

>NTDB_id=1138890 DQM56_RS03270 WP_111710432.1 663265..665520(-) (clpE) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGCTCTGTCAAAACTGTAATTTAAATGAATCAACCATTCATCTTTATACAAGCATTAACGGAAAGCAAAGGCAGATTGA
CCTCTGTCAAAATTGCTACCAAATCATGAAAACAGACCCTAAAAATCCTATCTTAGGAGGCTATAATGGCAACCAAAAGG
CGCAGCAGCCTTCTCAAAACCCTTTCTTTGATGACTTTTTTGGTGACCTCAACAACTTTAGAGCCTTTGGTCAGCTCCCC
AATACACCACCTACCCAATCAGGAGGCCAGCATGGCGGAGGTCACAACGGTGGCTATCGCCCCAATCAAACACAGCCAAC
ACAGGAGGCTAGCAAGGGGCTTCTGGAGGAATTCGGCATTAATATCACTGAAATGGCTAAGCGTGGTGATATTGACCCGG
TCATCGGACGAGATGATGAGATTATCCGCGTCATCGAAATTCTCAACCGTCGTACCAAAAATAACCCTGTCCTAATCGGT
GAGCCTGGAGTTGGTAAGACTGCTGTCGTTGAAGGCCTTGCTCAAAAAATCGTTGATGGTGATGTGCCACAAAAGCTACA
GAGTAAGCAGGTGATTCGCCTTGATGTGGTTAGCCTCGTTCAGGGGACAGGTATTCGTGGCCAATTTGAAGAGCGCATGC
AAAAGCTCATGGAAGAAATCCGCAAGCGCCATGACGTGATTCTATTTATTGATGAAATCCATGAAATTGTGGGAGCTGGT
GCAGTTGGTGACGGCAGCATGGACGCAGGAAATATTTTAAAGCCAGCACTTGCTCGTGGTGAGCTTCAATTAGTGGGAGC
GACCACTCTCAATGAATACCGCATCATCGAAAAGGACGCAGCCCTTGAGCGACGCATGCAGCCGGTTAAGGTGGATGAGC
CTTCGGTTGAAGAAACAATCACGATCCTAAAAGGAATCCAAGCCAAATACGAGGACTATCACCATGTCAAATATAGCCAG
TCAGCTATCGAAGCAGCCGCCAACCTATCCAACCGCTATATTCAAGACCGCTTCTTGCCTGATAAGGCCATTGACCTACT
AGATGAGGCTGGCTCAAAAATGAACCTAACCCTTAACTTTGTTGACCCAAAAGACATTGATAAGCGTTTGATTGAGGCTG
AAAACCTCAAGACACAAGCCACACGTGATGAGGATTATGAGCGAGCAGCCTATTTCCGCGATCAAATCGCCAAATATAAA
GAAATGCAGGCTCAAAAGCTAGATGAGCAGGATATTCCAATCATCACTGACAAGACCATCGAAGCAATCGTTGAGCAAAA
AACCAATATTCCAGTTGGTGATTTAAAGGAAAAGGAACAATCACAGCTAGTCAATCTGGCCGCCGATCTCAAAAAGCATG
TTATCGGTCAAGACGATGCTGTTGATAAAATTGCAAAGGCGATCCGTCGCAATCGTGTTGGACTTGGAGCGCCAAATCGT
CCTATCGGCTCCTTCCTCTTTGTTGGCCCAACTGGTGTCGGAAAAACAGAGCTTTCCAAGCAATTAGCTATTGAGCTTTT
TGGCTCTGCTGATAATATGATTCGCTTTGACATGTCTGAATATATGGAAAAGCATGCTGTGGCTAAGCTTGTAGGTGCCC
CTCCAGGCTACGTTGGCTATGAGGAGGCAGGGCAGTTAACAGAGCAGGTACGCCGCAACCCTTACTCGCTCATTTTGTTA
GATGAGATTGAAAAGGCTCACCCTGATGTCATGCACATGTTTTTACAGGTCCTAGATGACGGTCGATTAACCGACGGACA
GGGACGTACCGTTAGCTTTAAGGACACTATTATCATCATGACATCAAATGCTGGCACTGGCAAAACAGAAGCCTCAGTAG
GCTTTGGCGCTGCTAGAGAAGGGCGGACAAACTCTGTTTTAGGAGAGCTCAGTCATTTCTTTAGCCCCGAGTTCATGAAT
CGCTTTGATGGCATTATTGAGTTTCAGCCACTAAGCAAGGACAATCTTTTACATATCGTTCATTTAATGCTCGATGATGT
TAACCACCGCCTTGCTCACAATAACATTCGCCTTGATGTCACCCAAAAGGTCAAAGAAAAGCTCGTTGAGCTAGGCTATG
ATCCTAAGATGGGAGCACGACCATTGCGCCGCACCATTCAGGACTACATTGAGGACGCCATTACTGACTTCTACCTTGAG
CACCCAGCAGAAAAAAACCTGCGAGCTGTCTTGACCTCTAATGGACACATTATAATCAAGCCTGTAGTCAAATCTCAGGC
GAAGCAGGCGGACTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-270)

• AAA lid domain (AAA_lid_9) (295-392)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	84.232	98.802	0.832
clpE	Streptococcus pneumoniae Rx1	82.361	100	0.827
clpE	Streptococcus pneumoniae D39	82.361	100	0.827
clpE	Streptococcus pneumoniae R6	82.361	100	0.827
clpE	Streptococcus pneumoniae TIGR4	82.228	100	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	75.532	100	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.074	90.146	0.451
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.729	85.486	0.399
clpC	Streptococcus pneumoniae Rx1	48.214	82.024	0.395
clpC	Streptococcus pneumoniae D39	48.214	82.024	0.395
clpC	Streptococcus pneumoniae TIGR4	48.052	82.024	0.394
clpC	Streptococcus mutans UA159	47.343	82.69	0.391
clpC	Streptococcus thermophilus LMD-9	46.508	83.888	0.39
clpC	Streptococcus thermophilus LMG 18311	46.19	83.888	0.387