Detailed information NTG1138889

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM56_RS03150
• Genome accession: NZ_LS483368
• Coordinates: 638117..639154 (+)
• Length: 345 a.a.
• NCBI ID: WP_014622492.1
• Uniprot ID: A0A6D2LSH8
• Organism: Streptococcus equi subsp. zooepidemicus strain NCTC6176
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 633117..644154

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM56_RS03125 (NCTC6176_00628)	-	633429..634760 (+)	1332	WP_012678324.1	dipeptidase	-
DQM56_RS03130 (NCTC6176_00629)	arcC	634778..635728 (+)	951	WP_012515218.1	carbamate kinase	-
DQM56_RS03135 (NCTC6176_00630)	asnA	635948..636940 (+)	993	WP_012515219.1	aspartate--ammonia ligase	-
DQM56_RS03140 (NCTC6176_00631)	rsmD	637110..637649 (+)	540	WP_012515220.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM56_RS03145 (NCTC6176_00632)	coaD	637639..638139 (+)	501	WP_043983724.1	pantetheine-phosphate adenylyltransferase	-
DQM56_RS03150 (NCTC6176_00633)	sepM	638117..639154 (+)	1038	WP_014622492.1	SepM family pheromone-processing serine protease	Regulator
DQM56_RS03155 (NCTC6176_00634)	-	639774..640388 (+)	615	WP_012678319.1	YutD family protein	-
DQM56_RS03160 (NCTC6176_00635)	rlmN	640392..641474 (+)	1083	WP_043029472.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM56_RS03165 (NCTC6176_00636)	-	641901..642350 (-)	450	WP_231872407.1	peptidase	-
DQM56_RS03170 (NCTC6176_00637)	-	642750..643280 (+)	531	WP_012515230.1	Dps family protein	-
DQM56_RS03175 (NCTC6176_00638)	-	643653..643886 (+)	234	WP_012515231.1	YqgQ family protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37450.05 Da
• Isoelectric Point: 9.2833

>NTDB_id=1138889 DQM56_RS03150 WP_014622492.1 638117..639154(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MKTIKKFKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSVLTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTP
FTEISTMEDTTGGYSDADYLRINRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQVISGDEVDFSTGGVGGPSAGLMF
TLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGGAGLKVAAAAAAGADIFFVPNNPVDKDVKKANPKAISNYEEAKKA
AKRLKTAMKIIPVKTVQDAISYLKK

Nucleotide

• Length: 1038 bp

>NTDB_id=1138889 DQM56_RS03150 WP_014622492.1 638117..639154(+) (sepM) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
ATGAAAACAATAAAAAAATTTAAATGGTGGCTGATTGGCTTTGTTGCCTTGCTTTTTCTACTGTTGACACTGTTTTTCCC
CTTGCCTTATTATATTGAAATGCCAGGTGGAGCCTATGATATTCGCTCGGTATTGACTGTCAATGGCAAAGAGGATAAGG
AAAAGGGAGCTTATCAGTTTGTTGTGGTGAGCCTCAGTCGGGCTACCTTGGCTAAATTGCTCTATGCTTGGCTAACGCCT
TTCACTGAGATTAGCACCATGGAAGATACTACTGGTGGCTATAGCGATGCTGATTACCTGCGAATTAATCGCTTTTATAT
GGAAACCTCTCAAAACAGCGCTGTTTACCAGGCCCTTACTCTAGCAGGTAAGGAGGTAAGCTTTGATTATAAGGGTGTTT
ATGTCTTAGACGTCAGCAAGGATTCTAGCTTTAAAGGTGTGCTGCACCTAGCAGATACAGTGACAGGTGTCAATGGTAAA
ACATTTACAACGTCTGCCGATCTGATTGATTATGTTTCTCATTTGACCTTGGGAGATGAGGTGCAGGTACAATTTACAAC
CGCTGGTGAGTCAAAGACTGAAAAAGGAAAGATTATTAAGCTTAAAAACGGTAAAAATGGGATTGGCATTACCCTGACAG
ACCACACACAGGTCATTTCTGGTGATGAGGTCGACTTTAGCACCGGAGGTGTGGGTGGACCAAGTGCAGGCTTGATGTTT
ACTCTTGATATTTATGATCAAATCAATCACGAAGACTTGCGCAAGGGACGTGTGATTGCTGGTACAGGAACCATTGGCAA
GGATGGAAAAGTTGGAGATATTGGCGGGGCGGGCCTAAAGGTGGCTGCCGCCGCCGCTGCTGGTGCTGATATTTTCTTTG
TTCCAAATAATCCTGTGGATAAGGACGTCAAAAAAGCAAATCCTAAGGCTATTAGCAATTACGAGGAGGCTAAAAAAGCA
GCTAAACGACTAAAGACAGCAATGAAAATTATTCCTGTGAAAACCGTTCAAGATGCTATAAGCTACCTTAAAAAATAG

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-311)

3D structure

• AlphaFold DB: A0A6D2LSH8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	70.145	100	0.701