Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQM56_RS00825 Genome accession   NZ_LS483368
Coordinates   145367..147808 (+) Length   813 a.a.
NCBI ID   WP_111710119.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC6176     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 140367..152808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM56_RS00795 (NCTC6176_00159) ahpF 140696..142228 (-) 1533 WP_111710117.1 alkyl hydroperoxide reductase subunit F -
  DQM56_RS00800 (NCTC6176_00160) ahpC 142249..142809 (-) 561 WP_012514798.1 alkyl hydroperoxide reductase subunit C -
  DQM56_RS10100 (NCTC6176_00162) - 143426..143776 (+) 351 WP_231142596.1 exotoxin OB-fold domain-containing protein -
  DQM56_RS10105 (NCTC6176_00163) - 143718..144152 (+) 435 WP_154231672.1 exotoxin beta-grasp domain-containing protein -
  DQM56_RS00815 (NCTC6176_00164) - 144531..144734 (+) 204 WP_111710915.1 cold-shock protein -
  DQM56_RS00820 (NCTC6176_00165) - 144906..145367 (+) 462 WP_012514800.1 CtsR family transcriptional regulator -
  DQM56_RS00825 (NCTC6176_00166) clpC 145367..147808 (+) 2442 WP_111710119.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM56_RS00830 - 148159..148329 (-) 171 WP_111710916.1 putative holin-like toxin -
  DQM56_RS00835 (NCTC6176_00169) - 148586..149017 (+) 432 WP_043029274.1 hypothetical protein -
  DQM56_RS00840 (NCTC6176_00171) - 149152..149583 (+) 432 WP_043039957.1 hypothetical protein -
  DQM56_RS00845 (NCTC6176_00172) - 149585..150874 (+) 1290 WP_111710121.1 hypothetical protein -
  DQM56_RS00850 (NCTC6176_00173) - 150856..151248 (+) 393 WP_043052649.1 hypothetical protein -
  DQM56_RS00855 (NCTC6176_00174) - 151229..151519 (+) 291 WP_037580586.1 hypothetical protein -
  DQM56_RS00860 (NCTC6176_00175) groES 151819..152106 (+) 288 WP_012514806.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 813 a.a.        Molecular weight: 90403.22 Da        Isoelectric Point: 6.3877

>NTDB_id=1138880 DQM56_RS00825 WP_111710119.1 145367..147808(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
MMTYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLAAMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQF
KPQSKALSEILAFAHAICQVTNEHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKEVSRMVQVLCRKTKNNPVLVGDA
GVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSG
IDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQYHNVTISDT
AVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQALLDGDMSKVSALLAKEDKQPKLKPTAVTE
DDMLHTLSKLSGIPLEKLTQADSKKYLNLEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTE
LAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFDEVEKAHPDIFNILLQV
LDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKAISQDHQAMEKRILEELKKAYRPEFINRIDEKVVFHS
LTQENMRDVVKIMVKPLIAVLAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGDLSSGQSLK
IGVSRGKLAFDIA

Nucleotide


Download         Length: 2442 bp        

>NTDB_id=1138880 DQM56_RS00825 WP_111710119.1 145367..147808(+) (clpC) [Streptococcus equi subsp. zooepidemicus strain NCTC6176]
GTGATGACTTATTCATTAAAGATGCAAGACATTTTTAATCAGGCTCAATTTCAGGCAGAGCGCTTTGATAGTCCCTACCT
TGAGACCTGGCACATTTTATTAGCTATGGTAGCTGTTGATCATTCTTTAGCAGCCATGGTTTTAAGCGAATTTGAACGAA
AGATCAGAGCTGAAGAGTATGAGGCAGCTGCCATTTTAGCTATGGGAAAAAGTCCCAAGGAGGTGACTTCTGTCCAATTC
AAGCCACAATCCAAGGCCTTATCAGAAATACTAGCATTTGCTCATGCTATCTGTCAGGTTACCAATGAGCATGAGGTTGG
CTCAGAGCATGTGCTCTTTGCTATTTTGCTCAATCCGGATATTATGGCCAGTCGTTTGTTAGAGTTGGCAGGCTACAGGC
TCAAGGATTCTGGCAAGGGAGAGCCTAGGTTTGCGGATTTACGTAAGGCTATTGAGCTAAATGCCGGCTATAGCAAGGAA
ACTATTAAGGCGATTCATGAGTTGCGTAAGCCTAAAAAGAGTAAATCAGTAGGCACCTTTTCTGAAATGATGAAGCCACA
GAGTACAGCTGGTGAGCTATCAGACTTTACAAGAGACCTGACAGAGATGGCAAGACAGGGCTTATTAGAGCCAGTCATCG
GACGAGAAAAAGAGGTGTCACGTATGGTTCAGGTGCTTTGTCGTAAGACGAAAAATAATCCTGTTCTTGTTGGTGATGCG
GGTGTCGGAAAAACTGCTCTAGCTTATGGCTTAGCGCAGCGAATTGCTAATGGAGCCATTCCTTATGAATTACAAGACAT
GCGTGTCTTGGAGCTTGACATGATGAGTGTGGTTGCAGGTACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATCAAC
TCATTGACGATATTGAAGCAGATGGCAAAATCATCTTGTTTGTCGATGAGCTACATACCATTATGGGATCAGGAAGTGGT
ATTGACAGCACTCTTGATGCAGCTAATATTCTAAAGCCAGCCCTTTCTCGCGGTACCCTGCATATGGTTGGTGCTACAAC
TCAAGAGGAATATCAAAAGCATATTGAAAAGGACGCAGCCCTTTCTCGTCGCTTTGCCAAAATATTGATTGAGGAGCCTA
GTGTTGAGGACGCTTATCAGATTTTGCTTGGCTTGAAGCCTTCCTATGAACAGTACCATAATGTAACAATCTCTGATACA
GCTGTCCATACTGCTGTGAAGCTGGCTCGGCGCTATTTGACAAGTAAGCAGCTTCCAGACTCAGCGATTGATCTGCTTGA
TGAAGCCAGTGCGATGGTGCAAAGTATGGTTAAAAAGACGCAGCCTGACTTTATAACACCGCTTGATCAAGCCCTGCTTG
ATGGTGATATGAGCAAGGTGTCAGCCCTTTTAGCCAAAGAGGATAAGCAACCAAAGCTAAAACCAACAGCAGTCACTGAA
GATGATATGTTACACACCTTAAGCAAGCTATCAGGTATTCCCCTAGAAAAACTAACTCAGGCGGATAGTAAAAAATACCT
GAATCTGGAAAAGGAATTGCATAAGCGTGTTGTTGGTCAGGAAATGGCTGTTTCTGCTATTGCACGAGCCATTCGTCGTA
ACCAGTCAGGCATTCGCACAGGCAGACGCCCGATTGGCTCCTTTATGTTTCTTGGTCCAACCGGTGTCGGAAAAACAGAG
CTAGCAAAGGCCTTGGCCGAATTACTCTTTGATGATGAGTCAGCCCTTATTCGTTTTGACATGTCTGAGTACATGGAAAA
ATTTGCAGCCTCTCGTCTCAATGGTGCTCCTCCTGGCTATGTTGGCTATGATGAAGGAGGCGAGCTAACCGAAAAGGTTA
GAAATAAGCCTTATGCCGTTCTTCTTTTTGATGAGGTCGAAAAGGCTCACCCAGACATCTTTAATATCCTGCTGCAGGTC
CTTGATGATGGTATGTTAACAGATAGTCGTGGACGTAAGGTTGATTTTTCAAACACGATTATTATCATGACGAGCAACCT
AGGAGCAACTGCTCTAAGAGATGATAAGACGGTTGGATTTGGCGCTAAAGCGATCAGCCAGGACCATCAAGCAATGGAAA
AGCGTATTTTAGAAGAATTGAAAAAGGCTTATCGGCCTGAATTTATCAACAGAATTGATGAGAAGGTGGTCTTCCATAGC
CTAACACAGGAAAACATGCGTGATGTGGTGAAAATTATGGTTAAGCCGCTGATTGCAGTCTTGGCAGAAAAGCATATTAG
CCTTAAGTTCCAGCCATCAGCTCTCAAGTACTTATCTGAAGCTGGTTACGATGTTGAAATGGGTGCTCGCCCACTTCGCC
GTACCTTGCAAACAGAGGTTGAGGACAGGTTAGCAGAATTAATGCTGTCAGGAGATTTATCAAGCGGTCAAAGCCTCAAG
ATTGGTGTATCACGTGGGAAGCTAGCTTTTGATATCGCTTAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(721-800)

ATPase family associated with various cellular activities (AAA) (AAA)

(235-367)

AAA lid domain (AAA_lid_9)

(374-457)

AAA domain (Cdc48 subfamily) (AAA_2)

(543-714)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(95-131)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-51)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

75.154

100

0.752
  clpC Streptococcus thermophilus LMD-9

72.059

100

0.723
  clpC Streptococcus thermophilus LMG 18311

71.814

100

0.721
  clpC Streptococcus pneumoniae Rx1

65.971

100

0.661
  clpC Streptococcus pneumoniae D39

65.971

100

0.661
  clpC Streptococcus pneumoniae TIGR4

65.848

100

0.659
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.507

100

0.499
  clpC Bacillus subtilis subsp. subtilis str. 168

43.952

100

0.451

Multiple sequence alignment