Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQM52_RS04570 Genome accession   NZ_LS483367
Coordinates   884564..886663 (-) Length   699 a.a.
NCBI ID   WP_111681668.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 879564..891663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM52_RS04540 (NCTC5371_00923) - 880061..880900 (+) 840 WP_003054196.1 thymidylate synthase -
  DQM52_RS04545 (NCTC5371_00924) - 880981..881478 (+) 498 WP_111681666.1 dihydrofolate reductase -
  DQM52_RS04550 (NCTC5371_00925) - 881498..881668 (+) 171 WP_003054200.1 hypothetical protein -
  DQM52_RS04555 (NCTC5371_00926) clpX 881782..883011 (+) 1230 WP_003054192.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  DQM52_RS04560 (NCTC5371_00927) yihA 883021..883620 (+) 600 WP_003061604.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  DQM52_RS04565 (NCTC5371_00928) - 883764..884507 (+) 744 WP_111681667.1 hypothetical protein -
  DQM52_RS04570 (NCTC5371_00929) clpC 884564..886663 (-) 2100 WP_111681668.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM52_RS04575 - 887161..887568 (-) 408 Protein_841 IS30 family transposase -
  DQM52_RS04580 - 887562..887780 (+) 219 Protein_842 IS30 family transposase -
  DQM52_RS04585 (NCTC5371_00932) rplJ 888067..888567 (+) 501 WP_003050354.1 50S ribosomal protein L10 -
  DQM52_RS04590 rplL 888632..888997 (+) 366 WP_003043797.1 50S ribosomal protein L7/L12 -
  DQM52_RS04605 (NCTC5371_00936) - 890581..890826 (+) 246 Protein_846 helical hairpin domain-containing protein -

Sequence

Protein


Download         Length: 699 a.a.        Molecular weight: 77367.04 Da        Isoelectric Point: 4.8562

>NTDB_id=1138845 DQM52_RS04570 WP_111681668.1 884564..886663(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
MTNYYDKDTFGNMDDIFNQLMGNMGGYRSENRRYLVNGREMTPEEFQAYRQTGRLSDKGSEQPTSQGHQTKKDGILAKLG
TNLTEEARQGKLDPVIGRNHEIQDTAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
EAGTQYRGSFEENIQNMIQEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADMLKPALSRGELTLIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHNVILPDAVLKAAIDYSIQYIPQRSLPDKAIDLVDMTAAHLAA
QHPVTDLKSLEAEMTTQKNIQEEAVAKEDFERALTAKTRIEELQKQMDNHSEDQKVTATVNDIAESVERLTGVPVSNMGA
SDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGSKEAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRNPYAIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNT
VIIATSNAGFGYQEDENTDQPTIMDRIAPYFRPEFLNRFNGVIEFNHLQKEDLEEIVDLMLAEVNQTIAKKGISLAISDG
AKAHLIELGYDHAMGVRPLRRVIEQEIRDRITDFYLDHPEVKNLQASLEQGQLVIHDKN

Nucleotide


Download         Length: 2100 bp        

>NTDB_id=1138845 DQM52_RS04570 WP_111681668.1 884564..886663(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
ATGACAAATTATTATGACAAAGATACTTTTGGAAACATGGATGATATCTTTAATCAACTAATGGGCAATATGGGTGGCTA
TCGCAGTGAAAATCGACGCTATTTAGTGAACGGACGCGAAATGACACCTGAAGAATTCCAGGCATATCGTCAAACTGGAC
GTCTGAGCGATAAAGGTAGTGAACAACCTACATCCCAAGGTCATCAGACCAAAAAGGATGGGATTTTAGCTAAACTTGGC
ACCAACTTAACGGAAGAAGCAAGACAAGGAAAACTTGATCCTGTTATTGGTCGCAATCACGAAATTCAAGACACTGCGGA
AATTTTAGCTCGCCGAACAAAGAATAATCCTGTTCTAGTCGGAGATGCTGGTGTTGGTAAAACAGCTGTGGTTGAAGGGC
TAGCTCAAGCTATTGTGAATGGTGACGTCCCTGCTGCTATCAAAAATAAAGAAATCATTTCCATTGATATTTCTGGCCTT
GAAGCAGGCACTCAGTACCGTGGCTCCTTTGAAGAAAATATCCAAAACATGATTCAAGAGGTTAAAGAAGCTGGGAATAT
TATTCTTTTCTTTGATGAAATTCATCAAATCCTTGGTGCAGGTTCTACTGGTGGTGACTCTGGGTCTAAAGGATTAGCTG
ATATGCTAAAACCTGCTCTTTCCCGTGGTGAATTGACACTGATTGGCGCCACAACTCAAGATGAATACCGCAATACCATT
TTAAAAAATGCTGCGCTTGCTCGTCGTTTTAATGAGGTTAAGGTAAATGCACCGTCTGCTGAGGACACCTTCCATATTTT
AATGGGAATCCGAAATCTTTACGAACAACACCATAATGTTATCCTTCCGGATGCTGTTCTTAAAGCTGCGATTGACTATT
CTATTCAGTACATTCCTCAACGTAGTTTACCAGATAAAGCGATTGACTTAGTAGATATGACTGCTGCGCATTTAGCCGCT
CAGCATCCTGTGACTGACCTCAAGTCTCTAGAAGCTGAAATGACCACTCAAAAGAATATCCAAGAAGAGGCTGTGGCTAA
GGAAGATTTTGAGAGAGCTTTAACCGCTAAAACACGAATTGAAGAATTGCAAAAACAAATGGACAACCACAGCGAAGACC
AAAAGGTTACTGCTACTGTCAATGATATTGCAGAATCCGTAGAGCGCCTGACTGGTGTCCCAGTGTCCAATATGGGAGCT
AGTGATTTGGAAAGACTCAAAGAAATTAGCAACCGCTTAAAAGGACACGTGATTGGCCAAGATGGAGCTGTTGAAGCTGT
GGCTCGTGCTATTCGCCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCTATCGGTTCCTTCCTCTTTGTTGGACCAA
CAGGTGTCGGTAAGACAGAGTTAGCCAAACAGCTAGCACTGGACCTCTTTGGTTCCAAAGAGGCTATTATTCGACTTGAC
ATGTCCGAATACAGTGATCGTACTGCTGTGTCCAAGTTAATCGGGACAACTGCCGGTTATGTCGGTTATGATGATAATAA
CAATACGTTAACGGAACGAGTTCGTCGCAACCCGTATGCGATTGTTCTATTGGATGAGATTGAAAAAGCCGATCCGCAAG
TCATTACCCTTCTTCTCCAAGTACTGGATGATGGCCGATTAACAGATGGTCAGGGAAATACCATCAACTTTAAAAACACT
GTTATCATTGCTACTTCTAATGCTGGATTTGGGTATCAAGAAGATGAAAATACTGATCAACCTACTATTATGGACCGTAT
TGCGCCTTACTTTAGACCAGAGTTTCTCAATCGTTTCAATGGGGTTATCGAATTCAATCATCTGCAAAAAGAAGACTTAG
AAGAAATTGTTGATTTAATGTTAGCGGAAGTTAATCAAACCATAGCTAAAAAAGGAATCAGCTTAGCTATCTCTGATGGT
GCTAAAGCTCACTTGATTGAATTAGGTTATGACCACGCAATGGGAGTTCGACCATTACGCCGTGTCATCGAGCAAGAAAT
CCGAGACCGCATTACAGACTTTTACCTCGATCACCCAGAGGTCAAAAACTTACAAGCTAGTCTGGAACAAGGACAGTTAG
TCATTCACGACAAAAACTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(259-353)

AAA domain (Cdc48 subfamily) (AAA_2)

(443-600)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-679)

ATPase family associated with various cellular activities (AAA) (AAA)

(118-250)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

47.391

100

0.481
  clpE Streptococcus mutans UA159

46.544

100

0.472
  clpE Streptococcus pneumoniae Rx1

48.447

92.132

0.446
  clpE Streptococcus pneumoniae D39

48.447

92.132

0.446
  clpE Streptococcus pneumoniae R6

48.447

92.132

0.446
  clpE Streptococcus pneumoniae TIGR4

48.367

91.989

0.445
  clpC Bacillus subtilis subsp. subtilis str. 168

44.496

92.275

0.411
  clpC Streptococcus pneumoniae Rx1

40.943

97.139

0.398
  clpC Streptococcus pneumoniae D39

40.943

97.139

0.398
  clpC Streptococcus pneumoniae TIGR4

40.795

97.139

0.396
  clpC Streptococcus thermophilus LMG 18311

43.065

88.698

0.382
  clpC Streptococcus thermophilus LMD-9

43.065

88.698

0.382
  clpC Streptococcus mutans UA159

42.903

88.698

0.381
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.165

88.555

0.373

Multiple sequence alignment