Detailed information NTG1138795

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM60_RS08475
• Genome accession: NZ_LS483366
• Coordinates: 1822087..1823163 (-)
• Length: 358 a.a.
• NCBI ID: WP_002884703.1
• Uniprot ID: A0A1W5ZBL0
• Organism: Streptococcus salivarius strain NCTC7366
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1817087..1828163

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS08450 (NCTC7366_01707)	-	1817234..1818016 (+)	783	WP_014632681.1	ABC transporter ATP-binding protein	-
DQM60_RS08455 (NCTC7366_01708)	-	1818200..1820266 (-)	2067	WP_049529032.1	cation:proton antiporter	-
DQM60_RS08460 (NCTC7366_01709)	-	1820275..1820517 (-)	243	WP_002891697.1	hypothetical protein	-
DQM60_RS08465 (NCTC7366_01710)	-	1820514..1821062 (-)	549	WP_049529030.1	tRNA (mnm(5)s(2)U34)-methyltransferase	-
DQM60_RS08470 (NCTC7366_01711)	-	1821059..1822003 (-)	945	WP_014632678.1	TIGR01212 family radical SAM protein	-
DQM60_RS08475 (NCTC7366_01712)	sepM	1822087..1823163 (-)	1077	WP_002884703.1	SepM family pheromone-processing serine protease	Regulator
DQM60_RS08480 (NCTC7366_01713)	coaD	1823141..1823638 (-)	498	WP_014632676.1	pantetheine-phosphate adenylyltransferase	-
DQM60_RS08485 (NCTC7366_01714)	rsmD	1823671..1824219 (-)	549	WP_231910681.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM60_RS08490 (NCTC7366_01715)	trxB	1824359..1825279 (-)	921	WP_014632674.1	thioredoxin-disulfide reductase	-
DQM60_RS08495 (NCTC7366_01716)	-	1825345..1825569 (-)	225	WP_002884393.1	DUF4059 family protein	-
DQM60_RS08500 (NCTC7366_01717)	-	1825781..1826524 (-)	744	WP_014632672.1	amino acid ABC transporter ATP-binding protein	-
DQM60_RS08505 (NCTC7366_01718)	-	1826524..1827270 (-)	747	WP_096832659.1	amino acid ABC transporter permease	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 38988.67 Da
• Isoelectric Point: 9.2472

>NTDB_id=1138795 DQM60_RS08475 WP_002884703.1 1822087..1823163(-) (sepM) [Streptococcus salivarius strain NCTC7366]
MANKNESKSLLGKIWRIKWWLLSIFTVLFLLFALFFPLNNYYVELPGGAFDTKEVLTVDKKADDSKGSYNFVAVAQTKAT
LALMLYAQLNDFAKLQTAEEATGNYSDEDFMRINQFYMETSQNQAIYQGLTLAGKEASLEYMGVYVLQVADDSSFKGVLN
IADTVTAVNGKTFDNSADLIKYVQGLKLGSKVKVTYTTDDKEKTATGKIIKIANGKNGIGIGLTDHTEVKSPENVKFKLD
GVGGPSAGLMFTLAIYDQVSGQDLKAGRKIAGTGTIEKDGSVGDIGGAYLKVKSAADSGADIFFVPNNPVTKEMKKADPD
AKTNYQEAKEAAKKLGTKMKIVPVKTAQEAIDYLKKTK

Nucleotide

• Length: 1077 bp

>NTDB_id=1138795 DQM60_RS08475 WP_002884703.1 1822087..1823163(-) (sepM) [Streptococcus salivarius strain NCTC7366]
GTGGCAAACAAGAACGAATCTAAATCACTATTAGGGAAAATTTGGCGGATTAAGTGGTGGTTGTTAAGTATTTTTACGGT
ACTTTTCCTCCTATTTGCCCTCTTTTTCCCGCTAAATAATTATTATGTTGAGCTTCCGGGTGGTGCTTTTGATACTAAGG
AAGTCTTGACTGTAGACAAGAAAGCTGATGATTCAAAAGGATCCTACAATTTTGTGGCAGTGGCCCAAACCAAGGCGACT
TTAGCCTTGATGCTCTATGCTCAGCTTAATGATTTTGCAAAGCTTCAAACAGCTGAAGAGGCAACTGGGAATTACTCTGA
TGAAGATTTCATGCGTATCAACCAATTTTACATGGAGACTTCCCAAAACCAAGCGATTTATCAGGGCTTGACTCTGGCCG
GTAAGGAGGCTAGCTTGGAGTATATGGGTGTCTATGTGCTTCAGGTGGCTGATGATTCTAGCTTCAAGGGTGTCCTCAAT
ATTGCGGATACGGTGACAGCTGTCAATGGCAAGACCTTTGATAATTCTGCTGACTTGATTAAATACGTTCAAGGACTTAA
GCTGGGTTCAAAAGTCAAGGTCACTTATACGACAGATGACAAAGAAAAGACTGCCACTGGTAAGATTATCAAGATTGCCA
ATGGTAAAAATGGTATTGGTATCGGTTTGACAGATCATACCGAGGTTAAGAGTCCTGAAAATGTGAAGTTTAAACTTGAT
GGCGTTGGCGGACCAAGTGCGGGTCTTATGTTTACCCTAGCTATTTACGATCAGGTATCTGGTCAAGACCTCAAGGCTGG
CCGTAAGATTGCTGGAACAGGAACCATTGAAAAGGATGGTTCGGTCGGTGATATCGGTGGTGCCTACCTCAAGGTGAAAT
CAGCGGCTGATAGTGGTGCAGACATTTTCTTCGTGCCAAATAATCCAGTAACCAAGGAAATGAAAAAGGCTGATCCGGAT
GCCAAAACCAACTATCAAGAGGCCAAGGAAGCTGCCAAGAAACTGGGAACCAAGATGAAAATCGTCCCTGTTAAAACAGC
TCAAGAAGCCATTGATTATTTGAAAAAGACTAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (142-206)

3D structure

• AlphaFold DB: A0A1W5ZBL0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	65.396	95.251	0.623