Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DQM60_RS00555 Genome accession   NZ_LS483366
Coordinates   88933..91383 (+) Length   816 a.a.
NCBI ID   WP_070849930.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC7366     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 83933..96383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM60_RS00530 (NCTC7366_00104) ahpC 84831..85391 (-) 561 WP_084871103.1 alkyl hydroperoxide reductase subunit C -
  DQM60_RS00535 (NCTC7366_00105) rpsB 85664..86431 (+) 768 WP_002886342.1 30S ribosomal protein S2 -
  DQM60_RS00540 (NCTC7366_00106) tsf 86542..87582 (+) 1041 WP_002886343.1 translation elongation factor Ts -
  DQM60_RS00545 (NCTC7366_00107) - 87689..88159 (-) 471 WP_002886344.1 COG2426 family protein -
  DQM60_RS00550 (NCTC7366_00108) - 88477..88932 (+) 456 WP_014633783.1 CtsR family transcriptional regulator -
  DQM60_RS00555 (NCTC7366_00109) clpC 88933..91383 (+) 2451 WP_070849930.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DQM60_RS00560 (NCTC7366_00110) pbp3 91512..92768 (-) 1257 WP_045768740.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  DQM60_RS00565 (NCTC7366_00111) - 92987..93952 (-) 966 WP_045771628.1 IS3 family transposase -
  DQM60_RS00570 (NCTC7366_00112) - 93949..94626 (-) 678 WP_045771627.1 helix-turn-helix domain-containing protein -
  DQM60_RS00575 (NCTC7366_00113) pbp3 94710..95957 (-) 1248 WP_002886348.1 D-alanyl-D-alanine carboxypeptidase PBP3 -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90326.65 Da        Isoelectric Point: 5.7203

>NTDB_id=1138748 DQM60_RS00555 WP_070849930.1 88933..91383(+) (clpC) [Streptococcus salivarius strain NCTC7366]
MTTYSRKMQAIFHRAQLEAERFGSPFLETWHVLLAMVEVPGSVAYLTFTDFEDRIRAEEIETAAVLAMEKSPKDLSESDI
IDLRAQSHALEVMLQEAEGIASVTGAVEVGSEHVLMAFLLHKDLMVCRLLEVAGFQYKDDSDKPRIIDLRRSLERYAGLS
KQDLKAIHDLRKPKKSKASGNFANMMQPPQSSTGELSDYTKDLTAVAESGALDPVIGREKEISRMIQVLSRKTKNNPVLV
GEAGVGKTALALGLAQRIASGEVPFELADMRILELDMMSVVAGTRFRGDFEERMNQIIDEIEADGKIILFIDELHTIIGS
GSGIDSTLDAANILKPALARGTLHMVGATTQAEYQKHIEKDAALSRRFAKITIEEPSVPEAIDILKGLRSSYEDYHRVTI
TDEAVETAVKAAHRYLTSKNLPDSAIDLLDEASATVQGRIKKEAKREITPLDEALLSGDMKAAVKQYKASQKAKLPEPAL
VDADQIMQTLSRLSGIPVEKMTQADSKRYLNLEAELHKRVIGQDEAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVG
KTELAKALAEVLFDDESALLRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNIL
LQVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTIGFGAQDISHNHQAMQSRIMEELKKAYRPEFINRIDEKVV
FHSLEEEQLREIVKIMMKPLVSALAEKGIDLKFQPAALKHLAKDGYDVEMGARPLRRTIQTQVEDKLSELLLGGQVVSGQ
TLKIGCSKDKLTFTVV

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=1138748 DQM60_RS00555 WP_070849930.1 88933..91383(+) (clpC) [Streptococcus salivarius strain NCTC7366]
ATGACGACATATTCAAGAAAAATGCAGGCCATTTTCCATCGTGCTCAGCTTGAGGCAGAGCGTTTTGGAAGTCCTTTCTT
GGAGACTTGGCATGTGCTTCTGGCTATGGTTGAGGTTCCAGGATCTGTAGCCTACCTAACATTTACTGATTTTGAGGACC
GTATTCGTGCGGAAGAGATTGAGACAGCCGCTGTACTAGCGATGGAGAAAAGTCCAAAAGACTTGTCTGAATCCGATATT
ATCGATTTACGTGCACAGTCACATGCTTTAGAGGTTATGTTGCAAGAGGCAGAGGGAATTGCTAGTGTGACTGGTGCTGT
AGAGGTAGGGTCTGAACATGTATTGATGGCCTTCCTTCTTCATAAGGATTTGATGGTTTGTCGTCTCCTTGAAGTTGCTG
GTTTTCAATATAAGGATGACAGCGATAAGCCTCGTATTATCGATTTACGACGTTCTTTGGAGCGTTACGCAGGTCTTAGT
AAGCAAGATTTGAAGGCCATTCATGACCTTCGTAAGCCTAAAAAATCAAAGGCATCAGGAAATTTTGCTAATATGATGCA
GCCTCCTCAATCTTCTACTGGGGAACTGTCAGATTATACCAAGGACTTAACGGCAGTAGCCGAGTCAGGTGCTCTTGATC
CTGTTATTGGACGTGAGAAAGAAATTTCACGCATGATTCAGGTTTTGAGTCGTAAAACGAAGAATAACCCAGTTCTTGTG
GGTGAAGCAGGTGTTGGTAAGACGGCACTTGCGCTTGGCTTAGCACAGCGTATTGCTTCAGGCGAAGTACCTTTTGAGTT
GGCTGATATGCGTATCTTAGAGCTTGATATGATGAGTGTGGTTGCAGGAACACGTTTCCGTGGCGATTTCGAAGAACGTA
TGAATCAGATCATTGATGAGATTGAAGCTGATGGAAAAATCATTCTTTTTATTGACGAATTGCATACGATTATTGGTTCT
GGTTCAGGTATTGATAGCACCTTAGATGCGGCGAATATTTTGAAACCCGCTCTAGCACGTGGAACTCTTCATATGGTTGG
AGCAACTACTCAAGCTGAGTACCAGAAGCATATTGAGAAAGATGCAGCTCTTTCTCGCCGTTTTGCTAAGATTACAATTG
AGGAGCCAAGTGTACCTGAGGCGATTGATATTCTAAAAGGCCTACGTTCGTCTTATGAAGACTATCATCGTGTAACGATT
ACTGATGAGGCGGTTGAGACAGCAGTCAAGGCAGCCCACCGTTATTTGACGAGTAAAAACTTGCCTGACTCTGCCATTGA
TCTTTTAGATGAAGCGAGTGCAACTGTTCAAGGTCGTATCAAAAAAGAAGCCAAACGTGAGATAACGCCTTTGGATGAAG
CGCTTCTATCTGGTGATATGAAGGCTGCTGTTAAACAATATAAAGCTAGCCAAAAAGCAAAATTACCAGAACCTGCCTTG
GTAGATGCAGATCAGATTATGCAAACCCTTAGTCGTCTATCAGGTATTCCTGTTGAGAAGATGACTCAGGCAGATAGCAA
GCGTTACTTGAATCTGGAAGCAGAGCTTCATAAACGTGTTATTGGTCAAGACGAAGCAGTTTCAGCGATTAGTCGTGCTA
TTCGTCGTAACCAGTCAGGTATTCGTACTGGAAAACGTCCGATTGGTTCCTTCATGTTCCTTGGACCTACTGGTGTTGGT
AAGACAGAGTTGGCCAAGGCTTTGGCGGAAGTTCTCTTTGATGATGAGTCAGCTTTGCTTCGCTTTGACATGTCAGAATA
CATGGAAAAATTTGCGGCTAGCCGCCTTAATGGTGCTCCTCCAGGTTATGTTGGATATGATGAGGGTGGTGAATTAACAG
AGAAAGTTCGCAATAAGCCTTACTCAGTTCTCCTCTTTGACGAGGTGGAAAAGGCTCACCCAGATATTTTCAACATCCTC
TTACAGGTTTTGGATGATGGTGTCTTGACGGATAGTCGAGGTCGTAAAGTCGATTTCTCAAATACCATTATCATTATGAC
TTCGAACTTGGGAGCGACTGCTCTTCGTGATGATAAGACTATTGGATTTGGTGCCCAAGACATTTCTCATAATCACCAAG
CAATGCAGTCACGTATCATGGAAGAACTTAAGAAGGCCTACCGTCCAGAGTTTATCAACCGTATTGATGAGAAGGTTGTC
TTCCATAGTCTAGAGGAAGAGCAACTTCGTGAGATTGTCAAGATTATGATGAAACCGTTGGTATCAGCTTTGGCTGAAAA
AGGGATTGACTTGAAATTCCAACCAGCTGCTCTCAAGCATTTAGCTAAAGATGGCTATGATGTTGAGATGGGTGCTCGTC
CATTACGTCGCACGATTCAAACTCAAGTGGAGGACAAGTTATCTGAGCTCTTACTAGGTGGTCAAGTAGTTAGTGGACAA
ACTCTTAAAATCGGCTGCTCGAAAGATAAATTAACCTTTACAGTAGTGTAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(378-457)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(108-135)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(15-46)

ATPase family associated with various cellular activities (AAA) (AAA)

(238-370)

AAA domain (Cdc48 subfamily) (AAA_2)

(546-717)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(724-804)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus thermophilus LMG 18311

94.975

100

0.95
  clpC Streptococcus thermophilus LMD-9

94.853

100

0.949
  clpC Streptococcus mutans UA159

72.672

100

0.727
  clpC Streptococcus pneumoniae TIGR4

67.157

100

0.672
  clpC Streptococcus pneumoniae Rx1

67.034

100

0.67
  clpC Streptococcus pneumoniae D39

67.034

100

0.67
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.421

100

0.513
  clpC Bacillus subtilis subsp. subtilis str. 168

47.388

100

0.478
  clpE Streptococcus mutans UA159

47.764

76.716

0.366

Multiple sequence alignment