Detailed information NTG1138683

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM55_RS08570
• Genome accession: NZ_LS483364
• Coordinates: 1726328..1727371 (-)
• Length: 347 a.a.
• NCBI ID: WP_111676199.1
• Uniprot ID: A0A2X3YIH7
• Organism: Streptococcus sanguinis strain NCTC11086
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1721328..1732371

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM55_RS08550	trpB	1722407..1723588 (-)	1182	WP_111676191.1	tryptophan synthase subunit beta	-
DQM55_RS08555 (NCTC11086_01747)	-	1723978..1724493 (-)	516	WP_111676193.1	VanZ family protein	-
DQM55_RS08560 (NCTC11086_01748)	rlmN	1724480..1725568 (-)	1089	WP_111676195.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
DQM55_RS08565 (NCTC11086_01749)	-	1725565..1726146 (-)	582	WP_111676197.1	YutD family protein	-
DQM55_RS08570 (NCTC11086_01750)	sepM	1726328..1727371 (-)	1044	WP_111676199.1	SepM family pheromone-processing serine protease	Regulator
DQM55_RS08575 (NCTC11086_01751)	coaD	1727358..1727852 (-)	495	WP_002902590.1	pantetheine-phosphate adenylyltransferase	-
DQM55_RS08580 (NCTC11086_01752)	rsmD	1727842..1728390 (-)	549	WP_172454750.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM55_RS08585 (NCTC11086_01753)	-	1728460..1728948 (-)	489	WP_111676201.1	YcxB family protein	-
DQM55_RS08590 (NCTC11086_01754)	-	1729122..1729544 (+)	423	WP_111676203.1	DUF805 domain-containing protein	-
DQM55_RS08595 (NCTC11086_01755)	-	1729735..1729857 (-)	123	Protein_1618	YcxB family protein	-
DQM55_RS08600 (NCTC11086_01756)	-	1730000..1730677 (+)	678	WP_111676205.1	helix-turn-helix domain-containing protein	-
DQM55_RS08605 (NCTC11086_01757)	-	1730682..1732097 (+)	1416	WP_111676207.1	Y-family DNA polymerase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 37933.14 Da
• Isoelectric Point: 5.0267

>NTDB_id=1138683 DQM55_RS08570 WP_111676199.1 1726328..1727371(-) (sepM) [Streptococcus sanguinis strain NCTC11086]
MKRIKKFILPTVIGVTIAFFIAALYVRLPYYIEVPGGAEDVRQVLLVDNKADKEAGSYNFVTVGVEQATFAHLVYAWLTP
FTDIYSAKDMTGGSTDEEFNRINQFYMETSQNMAKYQGLTTAGKEIKMDYLGVYVLQVADNSTFKGVLNIADTVTGVNDK
TFESSEELVKYVNSQKLGDKIKVTFQEDGQEKSATGKIIKLENGKNGIGISLIDRTEVSSSIPITFSTEGIGGPSAGLMF
SLAIYTQLADPTLRDGRDIAGTGSISREGEVGEIGGIDKKVVSAAQSGADIFFAPNNELTEEEKKLSPNGKNNYQTALET
AKKIKTDMKIVPVKTLQDAIDYLKKNK

Nucleotide

• Length: 1044 bp

>NTDB_id=1138683 DQM55_RS08570 WP_111676199.1 1726328..1727371(-) (sepM) [Streptococcus sanguinis strain NCTC11086]
ATGAAAAGAATTAAGAAGTTTATATTGCCGACGGTCATTGGCGTCACTATTGCCTTTTTTATAGCAGCTCTTTACGTTCG
TCTGCCTTATTATATAGAAGTTCCTGGTGGTGCCGAGGATGTTCGTCAGGTCTTGCTGGTTGATAATAAGGCCGACAAGG
AAGCGGGTTCCTACAACTTTGTGACGGTCGGAGTAGAGCAGGCAACCTTTGCTCATCTGGTCTATGCTTGGCTGACCCCT
TTTACAGATATTTATTCTGCCAAGGATATGACGGGTGGCTCCACGGATGAGGAATTTAATCGGATCAACCAGTTTTACAT
GGAAACATCGCAAAATATGGCCAAATATCAAGGGTTGACGACAGCTGGTAAAGAGATTAAAATGGACTATCTAGGGGTTT
ATGTCCTGCAGGTGGCAGATAACTCAACTTTCAAGGGAGTTCTCAATATTGCTGATACGGTAACTGGTGTCAATGACAAG
ACATTTGAAAGTTCTGAGGAGCTGGTCAAGTATGTCAACTCGCAGAAGCTTGGGGATAAAATCAAGGTAACTTTCCAAGA
GGATGGCCAGGAGAAATCGGCAACCGGCAAGATTATCAAGTTGGAGAACGGTAAGAACGGGATTGGGATTAGTCTGATAG
ACCGGACGGAAGTCAGCAGCAGTATTCCGATTACATTTTCAACTGAAGGTATTGGCGGTCCCAGTGCTGGTCTCATGTTC
AGCCTAGCCATTTATACCCAGTTGGCTGATCCGACCCTTCGTGATGGCCGCGATATTGCAGGGACCGGCAGCATCAGTCG
TGAAGGCGAAGTTGGTGAAATCGGCGGAATTGATAAGAAAGTTGTTTCAGCGGCCCAAAGCGGAGCAGATATCTTCTTTG
CACCGAACAATGAACTGACAGAGGAAGAGAAGAAGCTTTCTCCTAATGGGAAAAACAACTACCAAACGGCTTTGGAGACA
GCCAAGAAGATTAAAACGGATATGAAAATTGTTCCAGTTAAAACGCTGCAGGACGCCATTGACTATCTGAAAAAGAACAA
GTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (128-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-300)

3D structure

• AlphaFold DB: A0A2X3YIH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	57.514	99.712	0.573