Detailed information NTG1138609

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM58_RS03850
• Genome accession: NZ_LS483363
• Coordinates: 705521..706558 (+)
• Length: 345 a.a.
• NCBI ID: WP_015017242.1
• Uniprot ID: A0A9X8T209
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 700521..711558

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM58_RS03830 (NCTC9414_00771)	arcC	702051..703001 (+)	951	WP_012767309.1	carbamate kinase	-
DQM58_RS03835 (NCTC9414_00772)	asnA	703328..704320 (+)	993	WP_003061055.1	aspartate--ammonia ligase	-
DQM58_RS03840 (NCTC9414_00773)	rsmD	704514..705053 (+)	540	WP_014612463.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM58_RS03845 (NCTC9414_00774)	coaD	705043..705534 (+)	492	WP_003051905.1	pantetheine-phosphate adenylyltransferase	-
DQM58_RS03850 (NCTC9414_00775)	sepM	705521..706558 (+)	1038	WP_015017242.1	SepM family pheromone-processing serine protease	Regulator
DQM58_RS03855 (NCTC9414_00776)	-	706839..707822 (+)	984	WP_003053684.1	LacI family DNA-binding transcriptional regulator	-
DQM58_RS03860 (NCTC9414_00777)	rbsK	707815..708726 (+)	912	WP_111681837.1	ribokinase	-
DQM58_RS03865 (NCTC9414_00778)	rbsD	708701..709099 (+)	399	WP_003051896.1	D-ribose pyranase	-
DQM58_RS03870 (NCTC9414_00779)	-	709115..710593 (+)	1479	WP_111706107.1	sugar ABC transporter ATP-binding protein	-
DQM58_RS03875 (NCTC9414_00780)	rbsC	710595..711536 (+)	942	WP_022554979.1	hypothetical protein	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37603.18 Da
• Isoelectric Point: 9.4270

>NTDB_id=1138609 DQM58_RS03850 WP_015017242.1 705521..706558(+) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
MKTIKKIKWWLISLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDISKDSTFKGTLNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSAEKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKDGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=1138609 DQM58_RS03850 WP_015017242.1 705521..706558(+) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC9414]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAGCCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTTTTTTTCCC
TCTTCCTTATTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAGTTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGATACCACAGGCGGTTATAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTAT
ATGTGTTAGATATTAGCAAGGATTCAACCTTTAAAGGTACTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAATAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGAGAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACATTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AGATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.594	100	0.716