Detailed information NTG1138547

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DQM53_RS10110
• Genome accession: NZ_LS483361
• Coordinates: 2046348..2048792 (-)
• Length: 814 a.a.
• NCBI ID: WP_111717685.1
• Uniprot ID: A0A9X8T0K2
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2041348..2053792

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM53_RS10090 (NCTC6179_02067)	-	2041704..2043200 (+)	1497	WP_111717682.1	C69 family dipeptidase	-
DQM53_RS10095 (NCTC6179_02068)	-	2043534..2044001 (+)	468	WP_111717683.1	8-oxo-dGTP diphosphatase	-
DQM53_RS10100 (NCTC6179_02069)	groL	2044219..2045844 (-)	1626	WP_012767614.1	chaperonin GroEL	-
DQM53_RS10105 (NCTC6179_02070)	groES	2045880..2046170 (-)	291	WP_111717684.1	co-chaperone GroES	-
DQM53_RS10110 (NCTC6179_02071)	clpC	2046348..2048792 (-)	2445	WP_111717685.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DQM53_RS10115 (NCTC6179_02072)	-	2048792..2049253 (-)	462	WP_003054759.1	CtsR family transcriptional regulator	-
DQM53_RS10120	-	2049449..2049652 (-)	204	WP_003053018.1	cold-shock protein	-
DQM53_RS10125 (NCTC6179_02074)	-	2050063..2051037 (+)	975	WP_111717686.1	amidohydrolase family protein	-
DQM53_RS10130 (NCTC6179_02075)	-	2051169..2051624 (+)	456	WP_111717687.1	MarR family transcriptional regulator	-
DQM53_RS10135 (NCTC6179_02076)	-	2051673..2052614 (+)	942	WP_111717688.1	2-keto-3-deoxygluconate permease	-
DQM53_RS10140 (NCTC6179_02077)	-	2052608..2053009 (+)	402	WP_126442244.1	GNAT family N-acetyltransferase	-
DQM53_RS10145 (NCTC6179_02078)	-	2053125..2053403 (+)	279	WP_111717690.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90151.65 Da
• Isoelectric Point: 6.4425

>NTDB_id=1138547 DQM53_RS10110 WP_111717685.1 2046348..2048792(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
MIMYSLKMQEIFRQAQFQAARFDSQHLETWHILLAMARVDHSLAGLVLSEFDAKVAVEEYEAAAILAMGKSPKDQVSHID
FRPQSKTLTNLLQFAQAISQVTKDQEVGSEHVLFAILLNPDIMATRLLEMAGYTIKDKGNGEPRLADLRKAIEIHAGYSK
EIIKAIHELRKPKKTKNQGSFSDMMKPPSTAGDLADFTRDLTEMASQGLLEPVIGRDAEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIESDGKIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNVEDAYQILLGLKGSYETYHNVTIAD
QAVSTAVKMAHRYLTSKNLPDSAIDLLDEASATVQGMVKKSSPEIITPLDQALIDGDMKKASRLLAKDVKGQHRKPTAVT
EEDILTTLSKLSGIPLEKLSQADSKKYLNLEKELHKRVIGQEDAVSAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDASALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGMLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGISHDHQAMEKRILEELKKAYRPEFINRIDEKVVFH
SLTQDNMREVVKIMVQPLIATLAEKGITLKFQPMALKYLSEEGYDVEMGARPLRRTLQTQVEDKLSELILAGELASGHTL
KIGLSHGKLSFNIE

Nucleotide

• Length: 2445 bp

>NTDB_id=1138547 DQM53_RS10110 WP_111717685.1 2046348..2048792(-) (clpC) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
ATGATCATGTATTCATTGAAGATGCAAGAAATTTTCAGGCAGGCGCAGTTTCAAGCAGCCCGCTTTGATAGCCAACACTT
AGAAACTTGGCATATATTGCTAGCTATGGCGAGGGTTGACCACTCCCTAGCGGGCTTGGTACTAAGCGAATTTGATGCTA
AGGTTGCAGTGGAAGAATATGAGGCTGCAGCTATTTTAGCGATGGGCAAAAGCCCTAAAGACCAAGTGTCTCACATTGAC
TTTAGGCCTCAGTCAAAAACCTTAACGAACCTTTTGCAATTTGCCCAAGCTATCAGTCAAGTCACCAAGGACCAAGAGGT
AGGTTCAGAGCATGTTCTCTTTGCCATTTTGCTTAATCCAGATATTATGGCGACTCGCTTATTAGAGATGGCGGGTTATA
CTATCAAGGATAAAGGAAACGGGGAGCCTCGCTTAGCTGATTTACGAAAAGCTATAGAGATTCATGCAGGCTATAGCAAG
GAAATAATTAAGGCTATCCACGAGTTGCGTAAGCCAAAGAAAACCAAGAATCAAGGTTCTTTTTCAGACATGATGAAACC
ACCAAGTACGGCTGGGGACTTGGCGGACTTTACACGTGATTTGACCGAGATGGCAAGCCAAGGTCTCTTAGAGCCAGTTA
TTGGCCGTGATGCTGAAGTATCACGGATGATTCAAGTACTGAGTCGTAAAACCAAGAATAACCCTGTTCTTGTGGGTGAC
GCAGGTGTGGGTAAAACGGCCCTTGCCTACGGCCTTGCCCAACGTATTGCTAATGGTGCTATTCCTTATGAACTGCAAGA
CATGCGTGTTCTAGAATTAGACATGATGAGTGTTGTTGCGGGGACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGACGATATTGAGTCAGATGGCAAGATTATTCTCTTCGTAGATGAATTGCACACCATTATGGGATCAGGAAGT
GGTATTGATAGCACGCTTGATGCTGCCAATATTTTAAAACCAGCCTTATCTCGTGGAACTCTCCATATGGTGGGTGCAAC
AACGCAGGAAGAATACCAAAAACACATTGAAAAAGATGCCGCTCTTTCGCGCCGCTTTGCTAAGATTTTAATTGAAGAAC
CTAATGTAGAAGATGCTTATCAGATTCTGCTAGGACTAAAAGGCTCTTACGAGACTTACCATAATGTTACCATTGCTGAT
CAGGCTGTTAGCACCGCTGTGAAAATGGCACATCGCTATCTGACCAGCAAAAACCTTCCGGATTCTGCCATTGATTTATT
GGATGAAGCCAGTGCTACAGTGCAAGGTATGGTTAAAAAATCTAGTCCAGAAATCATCACGCCATTAGATCAAGCTTTGA
TTGATGGCGATATGAAGAAGGCCTCTCGTTTGTTGGCAAAAGACGTTAAAGGGCAACATCGCAAGCCAACAGCTGTGACA
GAAGAGGACATCCTGACGACCTTGAGCAAGCTATCAGGTATTCCACTGGAAAAACTCAGCCAAGCTGATAGCAAAAAATA
CCTTAATTTGGAAAAAGAACTGCATAAGCGCGTGATTGGGCAAGAAGATGCTGTCTCAGCTATTTCTAGAGCCATTCGCC
GTAATCAGTCAGGCATTCGTACAGGTAAACGTCCAATCGGTTCTTTCATGTTCCTTGGTCCAACAGGGGTTGGTAAGACC
GAGTTGGCAAAAGCCTTGGCAGAAGTTCTCTTTGATGACGCGTCCGCCCTTATCCGCTTTGATATGTCAGAGTATATGGA
AAAATTTGCGGCTTCTCGCCTTAATGGCGCACCTCCAGGCTATGTTGGTTACGATGAAGGGGGTGAATTAACAGAGAAGG
TCAGAAACAAGCCTTATTCTGTGCTCCTCTTTGACGAGGTGGAAAAAGCTCACCCTGATATTTTCAACGTCCTCTTACAA
GTGCTTGATGATGGCATGTTGACAGATAGCCGTGGGCGTAAAGTGGACTTCTCAAACACCATTATTATCATGACAAGTAA
TCTAGGGGCAACAGCTCTGCGTGATGATAAAACAGTTGGCTTTGGGGCAAAAGGCATTAGCCATGACCACCAAGCCATGG
AAAAACGGATTTTGGAAGAGTTGAAGAAAGCTTACCGACCAGAATTTATCAACCGAATTGATGAAAAGGTTGTCTTCCAC
AGCCTCACTCAGGACAATATGAGAGAAGTGGTCAAGATTATGGTGCAACCGTTGATCGCTACTTTGGCAGAAAAAGGCAT
TACCCTCAAATTCCAGCCAATGGCCCTCAAGTATTTATCAGAAGAAGGGTATGATGTGGAAATGGGTGCTCGTCCATTGC
GCCGCACTTTGCAAACTCAAGTGGAAGATAAATTGTCTGAATTGATTCTTGCTGGTGAATTGGCAAGTGGTCATACCCTG
AAAATTGGCCTTTCTCATGGAAAACTCAGCTTTAACATTGAGTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA lid domain (AAA_lid_9) (376-462)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (15-53)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-137)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	76.753	99.877	0.767
clpC	Streptococcus thermophilus LMD-9	73.162	100	0.733
clpC	Streptococcus thermophilus LMG 18311	73.162	100	0.733
clpC	Streptococcus pneumoniae TIGR4	67.159	99.877	0.671
clpC	Streptococcus pneumoniae Rx1	67.159	99.877	0.671
clpC	Streptococcus pneumoniae D39	67.159	99.877	0.671
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	48.921	100	0.501
clpC	Bacillus subtilis subsp. subtilis str. 168	42.96	100	0.439