Detailed information NTG1138535

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: DQM53_RS07735
• Genome accession: NZ_LS483361
• Coordinates: 1542048..1543085 (-)
• Length: 345 a.a.
• NCBI ID: WP_111717149.1
• Uniprot ID: A0A380JVE1
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1537048..1548085

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM53_RS07710 (NCTC6179_01589)	rbsC	1537070..1538011 (-)	942	WP_111717140.1	ribose ABC transporter permease	-
DQM53_RS07715 (NCTC6179_01590)	-	1538013..1539491 (-)	1479	WP_111717142.1	sugar ABC transporter ATP-binding protein	-
DQM53_RS07720 (NCTC6179_01591)	rbsD	1539507..1539905 (-)	399	WP_111717144.1	D-ribose pyranase	-
DQM53_RS07725 (NCTC6179_01592)	rbsK	1539880..1540791 (-)	912	WP_111717147.1	ribokinase	-
DQM53_RS07730 (NCTC6179_01593)	-	1540784..1541767 (-)	984	WP_003051900.1	LacI family DNA-binding transcriptional regulator	-
DQM53_RS07735 (NCTC6179_01594)	sepM	1542048..1543085 (-)	1038	WP_111717149.1	SepM family pheromone-processing serine protease	Regulator
DQM53_RS07740 (NCTC6179_01595)	coaD	1543072..1543563 (-)	492	WP_111717151.1	pantetheine-phosphate adenylyltransferase	-
DQM53_RS07745 (NCTC6179_01596)	rsmD	1543553..1544092 (-)	540	WP_111717939.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
DQM53_RS07750 (NCTC6179_01597)	asnA	1544285..1545277 (-)	993	WP_003061055.1	aspartate--ammonia ligase	-
DQM53_RS07755 (NCTC6179_01598)	arcC	1545603..1546553 (-)	951	WP_111717153.1	carbamate kinase	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37544.11 Da
• Isoelectric Point: 9.5393

>NTDB_id=1138535 DQM53_RS07735 WP_111717149.1 1542048..1543085(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
MKTIKKIKWWLISLIALVALLIVLFFPLPYYVEMPGGAYDIRSVVKVNGKEDKDKGSYQFVAVSLSRASLAQLLYAWLTP
FTEISSVEDTTGGYSDADYIRINQFYMETSQNAAVYQALTLADKPVTLDYKGVYVLDVSKDSTFKGALNLADTVTGVNHK
QFTSSTELVDYVSHLKLGDKVTVQFISNSEPKSETGRIIKLKNGKNGIGIALTDHTKVNSADKIEFSTQGVGGPSAGLMF
TLDIYDQINKEDLRKGRHIAGTGTIGKNGEVGDIGGAGLKVVAAADAGAEIFFVPNNPVDKAVKKANPKAISNYEEAKRA
AKQLKTKMKIVPVTTVQDALAYLRQ

Nucleotide

• Length: 1038 bp

>NTDB_id=1138535 DQM53_RS07735 WP_111717149.1 1542048..1543085(-) (sepM) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6179]
ATGAAAACAATTAAAAAAATTAAATGGTGGCTGATTAGCCTAATTGCCCTCGTGGCTCTGCTTATCGTCCTCTTTTTCCC
TCTTCCTTACTATGTTGAAATGCCTGGCGGAGCCTATGACATTCGATCTGTGGTCAAGGTTAATGGCAAAGAAGATAAAG
ATAAAGGCTCCTATCAGTTTGTGGCAGTCAGTCTCAGTCGAGCCAGTTTAGCTCAATTGCTCTATGCTTGGCTAACCCCT
TTTACTGAAATCAGTTCAGTTGAGGACACCACAGGCGGTTACAGCGATGCAGACTATATCCGCATTAATCAATTCTACAT
GGAAACCTCACAAAATGCTGCGGTCTATCAGGCATTGACCTTGGCAGACAAACCAGTTACTTTGGACTACAAAGGGGTCT
ATGTGTTAGATGTTAGCAAGGATTCAACCTTTAAAGGTGCTTTAAACTTAGCAGATACGGTAACGGGAGTGAATCACAAA
CAATTTACGAGTTCAACAGAACTTGTGGACTATGTCTCTCATTTAAAACTTGGTGATAAGGTGACTGTGCAGTTTATTAG
TAATAGCGAACCTAAGTCTGAAACAGGTCGTATCATCAAACTAAAAAATGGTAAAAATGGTATCGGCATTGCTTTAACAG
ACCATACTAAAGTCAATTCAGCAGACAAAATCGAGTTTAGTACCCAAGGTGTTGGGGGTCCTAGCGCAGGCTTAATGTTT
ACACTAGATATCTACGACCAAATTAATAAAGAAGACCTTCGTAAAGGAAGACATATCGCCGGGACAGGAACCATTGGTAA
AAATGGTGAAGTTGGAGATATTGGCGGTGCGGGTCTTAAGGTCGTTGCTGCTGCAGATGCTGGTGCTGAGATTTTCTTTG
TGCCGAATAATCCTGTGGATAAAGCTGTTAAAAAAGCCAATCCAAAAGCTATTAGCAATTATGAAGAGGCCAAGCGAGCA
GCCAAGCAGTTAAAAACAAAAATGAAAATTGTTCCTGTAACAACTGTTCAGGATGCCCTAGCCTACCTTCGTCAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (130-192)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-299)

3D structure

• AlphaFold DB: A0A380JVE1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	71.884	100	0.719