Detailed information NTG1138459

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: DQM47_RS02205
• Genome accession: NZ_LS483360
• Coordinates: 420036..420761 (+)
• Length: 241 a.a.
• NCBI ID: WP_002983379.1
• Uniprot ID: A0A4U7HHL6
• Organism: Streptococcus pyogenes strain NCTC10876
• Function: export ComS (predicted from homology) Competence regulation

Genomic Context

Location: 415036..425761

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM47_RS02175 (NCTC10876_00430)	-	415215..416675 (+)	1461	WP_012560892.1	NCS2 family permease	-
DQM47_RS02180 (NCTC10876_00431)	tsaE	416829..417290 (+)	462	WP_002988647.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	-
DQM47_RS02185 (NCTC10876_00432)	-	417265..417789 (+)	525	WP_020905405.1	GNAT family N-acetyltransferase	-
DQM47_RS02190 (NCTC10876_00433)	brpA	417798..419081 (+)	1284	WP_002983372.1	biofilm formation/cell division transcriptional regulator BrpA	-
DQM47_RS02195 (NCTC10876_00434)	-	419192..419548 (-)	357	WP_002988657.1	hypothetical protein	-
DQM47_RS02200 (NCTC10876_00435)	-	419545..419964 (-)	420	WP_011285081.1	HIT family protein	-
DQM47_RS02205 (NCTC10876_00436)	pptA	420036..420761 (+)	726	WP_002983379.1	ABC transporter ATP-binding protein	Regulator
DQM47_RS02210 (NCTC10876_00437)	-	420764..421798 (+)	1035	WP_023610531.1	ABC transporter permease	-
DQM47_RS02215 (NCTC10876_00438)	ccrZ	421862..422653 (+)	792	WP_002983385.1	cell cycle regulator CcrZ	-
DQM47_RS02220 (NCTC10876_00439)	trmB	422653..423288 (+)	636	WP_002983387.1	tRNA (guanosine(46)-N7)-methyltransferase TrmB	-
DQM47_RS02230 (NCTC10876_00441)	rimP	423547..424083 (+)	537	WP_023610502.1	ribosome maturation factor RimP	-
DQM47_RS02235 (NCTC10876_00442)	nusA	424258..425415 (+)	1158	WP_002994325.1	transcription termination factor NusA	-
DQM47_RS02240 (NCTC10876_00443)	rnpM	425431..425727 (+)	297	WP_002983486.1	RNase P modulator RnpM	-

Sequence

Protein

• Length: 241 a.a.
• Molecular weight: 26678.75 Da
• Isoelectric Point: 4.5624

>NTDB_id=1138459 DQM47_RS02205 WP_002983379.1 420036..420761(+) (pptA) [Streptococcus pyogenes strain NCTC10876]
MLNIKNLTGGYHNIPVLNDVSFSVDNGELVGLIGLNGAGKSTTINEIIGFLKPYQGSISIDGLTLAENAVAYRQKIGFIP
ETPSLYEELTLSEHINTVAMAYDIDLEVAQKRAQPFLEMFRLTDKLEWFPVNFSKGMKQKVMIICAFVIDPSLFILDEPF
LGLDPLAISDLIQTLEVEKAKGKSILMSTHVLDSAERMCDRFVILHHGQVRAQGTLADLQEAFGDRSASLNDIYLALTKE
D

Nucleotide

• Length: 726 bp

>NTDB_id=1138459 DQM47_RS02205 WP_002983379.1 420036..420761(+) (pptA) [Streptococcus pyogenes strain NCTC10876]
ATGTTAAACATTAAAAATCTAACAGGAGGATATCACAATATCCCTGTTTTAAACGATGTCTCATTTTCTGTAGACAATGG
AGAGTTAGTCGGTTTGATCGGGCTAAATGGTGCTGGAAAGTCAACAACTATCAACGAAATTATTGGCTTTTTGAAGCCTT
ATCAAGGAAGTATTTCTATTGATGGTTTAACTCTAGCAGAAAATGCAGTTGCCTACCGTCAAAAAATAGGTTTTATCCCA
GAAACTCCTAGTCTCTATGAAGAATTGACCTTATCAGAGCATATCAACACCGTAGCTATGGCTTATGATATCGACTTAGA
AGTGGCACAAAAACGAGCACAACCTTTCTTGGAAATGTTTCGTTTAACTGACAAACTTGAATGGTTTCCTGTCAATTTTT
CTAAAGGGATGAAACAAAAAGTCATGATTATTTGTGCCTTTGTCATTGATCCAAGTCTATTTATTCTTGATGAACCATTC
TTAGGGTTAGACCCTTTAGCTATTTCAGACTTAATCCAAACGCTAGAAGTCGAAAAAGCAAAAGGAAAATCTATTTTGAT
GAGTACACATGTTTTGGACTCTGCTGAAAGAATGTGTGATCGCTTTGTGATTTTGCATCATGGACAAGTTCGTGCCCAAG
GAACTCTTGCTGACTTGCAAGAAGCTTTTGGTGACCGTTCAGCGAGCTTAAATGATATCTATCTTGCATTAACAAAAGAG
GATTAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: A0A4U7HHL6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.803	99.17	0.722
pptA	Streptococcus thermophilus LMD-9	71.967	99.17	0.714